LOCUS HUMIFI16A 2709 bp mRNA linear HUM 01-JAN-1995
DEFINITION Human interferon-gamma induced protein (IFI 16) gene, complete cds.
ACCESSION M63838
VERSION M63838.1
KEYWORDS interferon-gamma inducible protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Trapani,J.A., Browne,K.A., Dawson,M.J., Ramsay,R.G., Eddy,R.L.,
Show,T.B., White,P.C. and Dupont,B.
TITLE A novel gene constitutively expressed in human lymphoid cells is
inducible with interferon-gamma in myeloid cells
JOURNAL Immunogenetics 36 (6), 369-376 (1992)
PUBMED 1526658
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2709
/db_xref="H-InvDB:HIT000196084"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="CTL/NK cell"
gene 1..2709
/gene="IFI 16"
5'UTR 1..264
/gene="IFI 16"
CDS 265..2454
/gene="IFI 16"
/codon_start=1
/product="interferon-gamma induced protein"
/protein_id="AAA58683.1"
/translation="MGKKYKNIVLLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYD
KIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKKEKLKVKGPALSRKRKKEV
HATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAGPKGSKVSEEQTQPPSPAGAGMS
TAMGRSPSPKTSLSAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKPFEY
ETPEMEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEE
STVSEAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIY
EIQDDRGKMDVVGTGQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIKKKT
NPRNNDPKSMKLPQEQRQLPYPSEASTTFPESHLRTPQMPPTTPSSSFFTKKSEDTIS
KMNDFMRMQILKEGSHFPGPFMTSIGPAESHPHTPQMPPSTPSSSFLTTLKPRLKTEP
EEVSIEDSAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLKE
KFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCS
QTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLNTINCEEGDKLKLTSF
ELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSSMETSPDFFF"
regulatory 2677..2686
/regulatory_class="polyA_signal_sequence"
/gene="IFI 16"
BASE COUNT 960 a 542 c 548 g 659 t
ORIGIN
1 gggaatagca gaataggagc aagccagcac tagtcagcta actaagtgac tcaaccaagg
61 ccttttttcc ttgttatctt tgcagatact tcattttctt agcgtttctg gagattacaa
121 catcctgcgg ttccgtttct gggaacttta ctgatttatc tcccccctca cacaaataag
181 cattgattcc tgcatttctg aagatctcaa gatctggact actgttgaaa aaatttccag
241 tgaggctcac ttatgtctgt aaagatggga aaaaaataca agaacattgt tctactaaaa
301 ggattagagg tcatcaatga ttatcatttt agaatggtta agtccttact gagcaacgat
361 ttaaaactta atttaaaaat gagagaagag tatgacaaaa ttcagattgc tgacttgatg
421 gaagaaaagt tccgaggtga tgctggtttg ggcaaactaa taaaaatttt cgaagatata
481 ccaacgcttg aagacctggc tgaaactctt aaaaaagaaa agttaaaagt aaaaggacca
541 gccctatcaa gaaagaggaa gaaggaagtg catgctactt cacctgcacc ctccacaagc
601 agcactgtca aaactgaagg agcagaggca actcctggag ctcagaaaag aaaaaaatca
661 accaaagaaa aggctggacc caaagggagt aaggtgtccg aggaacagac tcagcctccc
721 tctcctgcag gagccggcat gtccacagcc atgggccgtt ccccatctcc caagacctca
781 ttgtcagctc cacccaacag ttcttcaact gagaacccga aaacagtggc caaatgtcag
841 gtaactccca gaagaaatgt tctccaaaaa cgcccagtga tagtgaaggt actgagtaca
901 acaaagccat ttgaatatga gaccccagaa atggagaaaa aaataatgtt tcatgctaca
961 gtggctacac agacacagtt cttccatgtg aaggttttaa acaccagctt gaaggagaaa
1021 ttcaatggaa agaaaatcat catcatatca gattatttgg aatatgatag tctcctagag
1081 gtcaatgaag aatctactgt atctgaagct ggtcctaacc aaacgtttga ggttccaaat
1141 aaaatcatca acagagcaaa ggaaactctg aagattgata ttcttcacaa acaagcttca
1201 ggaaatattg tatatggggt atttatgcta cataagaaaa cagtaaatca gaagaccaca
1261 atctacgaaa ttcaggatga tagaggaaaa atggatgtag tggggacagg acaatgtcac
1321 aatatcccct gtgaagaagg agataagctc cagcttttct gctttcgact tagaaaaaag
1381 aaccagatgt caaaactgat ttcagaaatg catagtttta tccagataaa gaaaaaaaca
1441 aacccgagaa acaatgaccc caagagcatg aagctacccc aggaacagcg tcagcttcca
1501 tatccttcag aggccagcac aaccttccct gagagccatc ttcggactcc tcagatgcca
1561 ccaacaactc catccagcag tttcttcacc aagaaaagtg aagacacaat ctccaaaatg
1621 aatgacttca tgaggatgca gatactgaag gaagggagtc attttccagg accgttcatg
1681 accagcatag gcccagctga gagccatccc cacactcctc agatgcctcc atcaacacca
1741 agcagcagtt tcttaaccac gttgaaacca agactgaaga ctgaacctga agaagtttcc
1801 atagaagaca gtgcccagag tgacctcaaa gaagtgatgg tgctgaacgc aacagaatca
1861 tttgtatatg agcccaaaga gcagaagaaa atgtttcatg ccacagtggc aactgagaat
1921 gaagtcttcc gagtgaaggt ttttaatatt gacctaaagg agaagttcac cccaaagaag
1981 atcattgcca tagcaaatta tgtttgccgc aatgggttcc tggaggtata tcctttcaca
2041 cttgtggctg atgtgaatgc tgaccgaaac atggagatcc caaaaggatt gattagaagt
2101 gccagcgtaa ctcctaaaat caatcagctt tgctcacaaa ctaaaggaag ttttgtgaat
2161 ggggtgtttg aggtacataa gaaaaatgta aggggtgaat tcacttatta tgaaatacaa
2221 gataatacag ggaagatgga agtggtggtg catggacgac tgaacacaat caactgtgag
2281 gaaggagata aactgaaact caccagcttt gaattggcac cgaaaagtgg gaataccggg
2341 gagttgagat ctgtaattca tagtcacatc aaggtcatca agaccaggaa aaacaagaaa
2401 gacatactca atcctgattc aagtatggaa acttcaccag actttttctt ctaaaatctg
2461 gatgtcattg acgataatgt ttatggagat aaggtctaag tccctaaaaa aatgtacata
2521 tacctggttg aaatacaaca ctatacatac acaccaccat atatactagc tgttaatcct
2581 atggaatggg ggtattggga gtgctttttt aatttttcat agtttttttt taataaaatg
2641 gcatattttg catctacaac ttctataata agaaaaaata aataaacatt atcttttttg
2701 tgaaaaaaa
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