LOCUS HUMRPA70KD 2393 bp mRNA linear HUM 03-AUG-1993
DEFINITION Human replication protein A 70kDa subunit mRNA complete cds.
ACCESSION M63488
VERSION M63488.1
KEYWORDS replication protein A.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2393)
AUTHORS Erdile,L.F., Heyer,W.D., Kolodner,R. and Kelly,T.J.
TITLE Characterization of a cDNA encoding the 70-kDa single-stranded
DNA-binding subunit of human replication protein A and the role of
the protein in DNA replication
JOURNAL J. Biol. Chem. 266 (18), 12090-12098 (1991)
PUBMED 2050703
COMMENT Original source text: Human, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2393
/db_xref="H-InvDB:HIT000196073"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 70..1920
/codon_start=1
/product="replication protein A, 70-kDa subunit"
/protein_id="AAA36584.1"
/translation="MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRL
LMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVL
KSAEAVGVKIGNPVPYNEGLGQPQVAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYG
ASKTFGKAAGPSLSHTSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGE
GKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDY
EMTFNNETSVMPCEDDHHLPTVQFDFTGIDDLENKSKDSLVDIIGICKSYEDATKITV
RSNNREVAKRNIYLMDTSGKVVTATLWGEDADKFDGSRQPVLAIKGARVSDFGGRSLS
VLSSSTIIANPDIPEAYKLRGWFDAEGQALDGVSISDLKSGGVGGSNTNWKTLYEVKS
ENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDTEFP
NFKYRMILSVNIADFQENQWVTCFQESAEAILGQNAAYLGELKDKNEQAFEEVFQNAN
FRSFIFRVRVKVETYNDESRIKATVMDVKPVDYREYGRRLVMSIRRSALM"
BASE COUNT 640 a 557 c 635 g 561 t
ORIGIN
1 cggcgcggga cccgggtggg gaagctggag ctgttgcggg gtccgcgggg aagtcttggc
61 ggtggagcca tggtcggcca gctgagcgag ggggccattg cggccatcat gcagaagggg
121 gatacaaaca taaagcccat cctccaagtc atcaacatcc gtcccattac tacggggaat
181 agtccgccgc gttatcgact gctcatgagt gatggattga acactctatc ctctttcatg
241 ttggcgacac agttgaaccc tctcgtggag gaagaacaat tgtccagcaa ctgtgtatgc
301 cagattcaca gatttattgt gaacactctg aaagacggaa ggagagtagt tatcttgatg
361 gaattagaag ttttgaagtc agctgaagca gttggagtga agattggcaa tccagtgccc
421 tataatgaag gactcgggca gccgcaagta gctcctccag cgccagcagc cagcccagca
481 gcaagcagca ggccccagcc gcagaatgga agctcgggaa tgggttctac tgtttctaag
541 gcttatggtg cttcaaagac atttggaaaa gctgcaggtc ccagcctgtc acacacttct
601 gggggaacac agtccaaagt ggtgcccatt gccagcctca ctccttacca gtccaagtgg
661 accatttgtg ctcgtgttac caacaaaagt cagatccgta cctggagcaa ctcccgaggg
721 gaagggaagc ttttctccct agaactggtt gacgaaagtg gtgaaatccg agctacagct
781 ttcaatgagc aagtggacaa gttctttcct cttattgaag tgaacaaggt gtattatttc
841 tcgaaaggca ccctgaagat tgctaacaag cagttcacag ctgttaaaaa tgactacgag
901 atgaccttca ataacgagac ttccgtcatg ccctgtgagg acgaccatca tttacctacg
961 gttcagtttg atttcacggg gattgatgac ctcgagaaca agtcgaaaga ctcacttgta
1021 gacatcatcg ggatctgcaa gagctatgaa gacgccacta aaatcacagt gaggtctaac
1081 aacagagaag ttgccaagag gaatatctac ttgatggaca catccgggaa ggtggtgact
1141 gctacactgt ggggggaaga tgctgataaa tttgatggtt ctagacagcc cgtgttggct
1201 atcaaaggag cccgagtctc tgatttcggt ggacggagcc tctccgtgct gtcttcaagc
1261 actatcattg cgaatcctga catcccagag gcctataagc ttcgtggatg gtttgacgca
1321 gaaggacaag ccttagatgg tgtttccatc tctgatctaa agagcggcgg agtcggaggg
1381 agtaacacca actggaaaac cttgtatgag gtcaaatccg agaacctggg ccaaggcgac
1441 aagccggact actttagttc tgtggccaca gtggtgtatc ttcgcaaaga gaactgcatg
1501 taccaagcct gcccgactca ggactgcaat aagaaagtga ttgatcaaca gaatggattg
1561 taccgctgtg agaagtgcga caccgaattt cccaatttca agtaccgcat gatcctgtca
1621 gtaaatattg cagattttca agagaatcag tgggtgactt gtttccagga gtctgctgaa
1681 gctatccttg gacaaaatgc tgcttatctt ggggaattaa aagacaagaa tgaacaggca
1741 tttgaagaag ttttccagaa tgccaacttc cgatctttca tattcagagt cagggtcaaa
1801 gtggagacct acaacgacga gtctcgaatt aaggccactg tgatggacgt gaagcccgtg
1861 gactacagag agtatggccg aaggctggtc atgagcatca ggagaagtgc attgatgtga
1921 gaggagcagt gccaatcggg cagaagtttg caaataggca gaatggaatc gatttcctcc
1981 cacctccgtg tgacgatccc atgttagcta cacagtgcag aggctcttga tggtggacta
2041 agcaattcct ccctcgtgcg catctcagaa cccatcggta ggcaaaggaa aatacgctca
2101 ggtggttgtg gtgtagactg tgtcaggcct acggagtcag ccagtggcta gcgcaagacc
2161 agtcactccc tctgccttca ggcttctgtc aatttcatta tcatcaagca ggaattatgt
2221 cgtaagtcac tgaccctaac tgcagaccat gaagtaaatt atgtaactag gtttttgctt
2281 ctccagtggt gaccaccccc ccccatcccc gctcacaact tgggttcttc tcagcggggc
2341 gagctgagaa gcggtcatga gcacctgggg attttagtaa gtgtgtcttc cta
//