LOCUS HUMTCL3 2898 bp mRNA linear HUM 03-AUG-1993
DEFINITION Human T lymphocyte homeobox protein mRNA, partial cds.
ACCESSION M62626
VERSION M62626.1
KEYWORDS homeobox protein; proto-oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2898)
AUTHORS Lu,M., Gong,Z.Y., Shen,W.F. and Ho,A.D.
TITLE The tcl-3 proto-oncogene altered by chromosomal translocation in
T-cell leukemia codes for a homeobox protein
JOURNAL EMBO J. 10 (10), 2905-2910 (1991)
PUBMED 1717256
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2898
/db_xref="H-InvDB:HIT000196022"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="T lymphocyte"
/germline
CDS 1019..2011
/function="DNA binding"
/note="homeobox is located at positions 1616-1798."
/codon_start=1
/product="homeobox protein"
/protein_id="AAA36719.1"
/translation="MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGE
YGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYN
VNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSV
PAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEK
RFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILL
QLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE"
BASE COUNT 590 a 933 c 780 g 595 t
ORIGIN
1 cctctttcga accctgtagg attttacttc ttgacgcatc tgtttattta aaccaaaggg
61 gtatgttgag gcatgggcac cctggcagca gaccccaaac caaccctctt gacttgtgcc
121 tgccttcagg atatgttcct tcctgaattg tctaagaagg ctgagttggg ggggtggttg
181 ctgattttta taacatatag cagttgttca taggcctgtg ttttaaagaa gggcaagcct
241 gaactaccgt cctgcctagg cctggctcca tacctgggag tagacagtct tctactttct
301 aaaaactgac ttaaatttga taaatctcct gttgagtgac agtgtttcgc agctgagccc
361 ttaaggagat tctcagttgg gcagagacat cccttcctca gacgccttgt gggctggact
421 cctttggccc agttcaaagt gaggggaggg ctccaacagg ccgggaagac agttgacttc
481 accctccttg ggtttgtctg tctgtccgtc tctgggaatg gtcgcttcct gttttccctt
541 ttccttttaa gcctcgcctt gttccctctt ctctctcttc atgaactact ccgagtcttg
601 gtctccgtcc ctctatctct ggctcctgca tctgtcctcg gcttctggcc ttcctctccc
661 cctcccctcc cctccctcgc gctgtcattc accccgctcc tctccgcgca cagccaatgg
721 agagacccag tcgaaacgcg aagctctctt gcaccgggct ttttcgcctg gtgattgatg
781 tcccagagtc aacagcgagc gagcagccgg agcggggaag cagaagccag agaggggaag
841 aatacggcgc cccctctctc cctcccctcc cccttctact ttagcctttc tgcgcacttc
901 gcttccaagt ctccgcgcag ccaggagccg ctgttgcctc ccagcccctg ctagctgccc
961 cccgagccga gcgcagcgag cgccgccgcc cgggcccccc ggtggggcca gggccagcat
1021 ggagcacctg ggtccgcacc acctccaccc gggtcacgca gagcccatta gcttcggcat
1081 cgaccagatc ctcaacagcc cggaccaggg tggctgcatg ggacccgcct cgcgcctcca
1141 ggacggagaa tacggccttg gctgcttggt cggaggcgcc tacacttacg gcggcggggg
1201 ctccgcggcc gcgacggggg ctggaggagc gggggcctat ggtactggag gtcccggcgg
1261 ccccggaggc ccggcaggcg gcggcggcgc ctgcagcatg ggtcctctga ccggctccta
1321 caacgtgaac atggccttgg caggcggccc cggtcctggc ggcggcggcg gcagcagcgg
1381 cggtgccggg gcactcagcg ctgcgggggt aatccgggtg ccggcacaca ggccgctcgc
1441 cggagctgtg gcccaccccc agcccctggc caccggcttg cccaccgtgc cctctgtgcc
1501 tgccatgccg ggcgtcaaca acctcactgg cctcaccttc ccctggatgg agagtaaccg
1561 cagatacaca aaggacaggt tcacaggtca cccctatcag aaccggacgc cccccaagaa
1621 gaagaagccg cgcacgtcct tcacacgcct gcagatctgc gagctggaga agcgcttcca
1681 ccgccagaag tacctggcct cggccgagcg cgccgccctg gccaaggcgc tcaaaatgac
1741 cgatgcgcag gtcaaaacct ggttccagaa ccggcggaca aagtggagac ggcagactgc
1801 ggaggaacgg gaggccgaga ggcagcaagc gaaccgcatc ctcctgcagt tgcagcagga
1861 ggccttccag aagagcctgg cacagccgct gcccgctgac cctctgtgcg tgcacaactc
1921 gtcgctcttc gccctgcaga atctgcagcc gtggtctgac gactcgacca aaatcactag
1981 cgtcacgtcg gtggcgtcgg cctgcgagtg agcctgccca ttctgccctg tgggacccca
2041 ggcccactca ggggtcactg aggcctgaga cccaggactc ctccccaccc tcctggcctc
2101 agactgcacc caggagggga acactgccct cgcacgcccc aaagggcccc cacatttgtg
2161 ccgacactgt tctccttcgg tggaagagct caagggacaa ggacacgcgc ccccctccca
2221 gaggcgtccc gcacctgtct gaactgttaa gaaatctgtt tttgtttatt tcattttatt
2281 ttaattttta acgtgggatt cagagaaagg caagggaggt aagggaggag gagcttctgg
2341 ggtccccagg gctgtcatct gaatttgccc tgggaaaccc cttctctgtg acccacttct
2401 catcacacac acatggaaac ccataggtcc acacacaggt ggtgttactg tccctcctgg
2461 tgtcacccca gagccacaca tgggcatcta tgggagagtg tcaaccagac agagggtcac
2521 agtgtttaca ctttggacct tacgatcagg cacaggtcag gggtgacaca gactcatcct
2581 gaacagcatg gcactgggtc cagcacaaac acaaggtcat ggccacactg tgacacacta
2641 caccacacac aacagccaac agctacaaca gcctcacttg gtctgccagg cccccaccac
2701 acatcccagc ccaatccagg tacgcacaga caggttttca cataaatgca gcccatttct
2761 ccagaaccca tttgaggggt gggggggtgt taatttatgc acttataagg tgttttctgt
2821 gtaaccattt tataaagtgc ttgtgtaatt tatgtgaaaa aaataaataa aagcctcaaa
2881 agcctccgga aaaaaaaa
//