LOCUS HUMWRSAA 1959 bp mRNA linear HUM 14-JAN-1995
DEFINITION Human tryptophanyl-tRNA synthetase (WRS) mRNA, complete cds.
ACCESSION M61715
VERSION M61715.1
KEYWORDS transfer RNA-Trp synthetase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1959)
AUTHORS Frolova,L.Yu., Sudomoina,M.A., Grigorieva,A.Yu., Zinovieva,O.L. and
Kisselev,L.L.
TITLE Cloning and nucleotide sequence of the structural gene encoding for
human tryptophanyl-tRNA synthetase
JOURNAL Gene 109 (2), 291-296 (1991)
PUBMED 1765274
COMMENT Original source text: Human fibroblast, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1959
/db_xref="H-InvDB:HIT000195979"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="14q21-qter"
gene 1..1959
/gene="WARS"
CDS 188..1603
/gene="WARS"
/EC_number="6.1.1.2"
/codon_start=1
/product="transfer RNA-Trp synthetase"
/protein_id="AAA61298.1"
/db_xref="GDB:G00-119-632"
/translation="MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLV
SLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDK
LIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYT
GRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYGDAVEN
AKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIG
KISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPAL
LHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGG
NCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRK
EVTDEIVKEFMTPRKLSFDFQ"
BASE COUNT 518 a 508 c 479 g 454 t
ORIGIN Chromosome 14.
1 cgaaaaaaga ggggaagagt attaaagacc atttctggct gggcagggca ctctcagcag
61 ctcaactgcc cagcgtgacc agtggccacc tctgcagtgt cttccacaac ctggtcttga
121 ctcgtctgct gaacaaatcc tctgacctca ggccggctgt gaacgtagtt cctgagagat
181 agcaaacatg cccaacagtg agcccgcatc tctgctggag ctgttcaaca gcatcgccac
241 acaaggggag ctcgtaaggt ccctcaaagc gggaaatgcg tcaaaggatg aaattgattc
301 tgcagtaaag atgttggtgt cattaaaaat gagctacaaa gctgccgcgg gggaggatta
361 caaggctgac tgtcctccag ggaacccagc acctaccagt aatcatggcc cagatgccac
421 agaagctgaa gaggattttg tggacccatg gacagtacag acaagcagtg caaaaggcat
481 agactacgat aagctcattg ttcggtttgg aagtagtaaa attgacaaag agctaataaa
541 ccgaatagag agagccaccg gccaaagacc acaccacttc ctgcgcagag gcatcttctt
601 ctcacacaga gatatgaatc aggttcttga tgcctatgaa aataagaagc cattttatct
661 gtacacgggc cggggcccct cttctgaagc aatgcatgta ggtcacctca ttccatttat
721 tttcacaaag tggctccagg atgtatttaa cgtgcccttg gtcatccaga tgacggatga
781 cgagaagtat ctgtggaagg acctgaccct ggaccaggcc tatggcgatg ctgttgagaa
841 tgccaaggac atcatcgcct gtggctttga catcaacaag actttcatat tctctgacct
901 ggactacatg gggatgagct caggtttcta caaaaatgtg gtgaagattc aaaagcatgt
961 taccttcaac caagtgaaag gcattttcgg cttcactgac agcgactgca ttgggaagat
1021 cagttttcct gccatccagg ctgctccctc cttcagcaac tcattcccac agatcttccg
1081 agacaggacg gatatccagt gccttatccc atgtgccatt gaccaggatc cttactttag
1141 aatgacaagg gacgtcgccc ccaggatcgg ctatcctaaa ccagccctgt tgcactccac
1201 cttcttccca gccctgcagg gcgcccagac caaaatgagt gccagcgacc caaactcctc
1261 catcttcctc accgacacgg ccaagcagat caaaaccaag gtcaataagc atgcgttttc
1321 tggagggaga gacaccatcg aggagcacag gcagtttggg ggcaactgtg atgtggacgt
1381 gtctttcatg tacctgacct tcttcctcga ggacgacgac aagctcgagc agatcaggaa
1441 ggattacacc agcggagcca tgctcaccgg tgagctcaag aaggcactca tagaggttct
1501 gcagcccttg atcgcagagc accaggcccg gcgcaaggag gtcacggatg agatagtgaa
1561 agagttcatg actccccgga agctgtcctt cgactttcag tagcactcgt tttacatatg
1621 cttataaaag aagtgatgta tcagtaatgt atcaataatc ccagcccagt caaagcaccg
1681 ccacctgtag gcttctgtct catggtaatt actgggcctg gcctctgtaa gcctgtgtat
1741 gttatcaata ctgtttcttc ctgtgagttc cattatttct atctcttatg ggcaaagcat
1801 tgtgggtaat tggtgctggc taacattgca tggtcggata gagaagtcca gctgtgagtc
1861 tctccccaaa gcagccccac agtggagcct tcggctggaa gtccatgggc caccctgttc
1921 ttgtccatgg aggacttccg agggttccaa gtatactct
//