LOCUS HUMNF1AA 1483 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human neurofibromatosis type 1 (NF1) mRNA, complete cds.
ACCESSION M61213
VERSION M61213.1
KEYWORDS neurofibromatosis protein type 1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1483)
AUTHORS Martin,G.A., Viskochil,D., Bollag,G., McCabe,P.C., Crosier,W.J.,
Haubruck,H., Conroy,L., Clark,R., O'Connell,P., Cawthon,R.M.,
Innis,M.A. and McCormick,F.
TITLE The GAP-related domain of the neurofibromatosis type 1 gene product
interacts with ras p21
JOURNAL Cell 63 (4), 843-849 (1990)
PUBMED 2121370
COMMENT Original source text: Human, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1483
/db_xref="H-InvDB:HIT000195978"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1483
/gene="NF1"
CDS 19..1467
/gene="NF1"
/codon_start=1
/product="neurofibromatosis protein type 1"
/protein_id="AAA59923.1"
/translation="MEAKSQLFLKYFTLFMNLLNDCSEVEDESAQTGGRKRGMSRRLA
SLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLA
ETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQ
LLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSD
WQHVSFEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQV
VSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIA
NHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFISDGNVLALH
RLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTS
SKFEEFMTRHQVHEKEEFKALKTLTPPPEPET"
BASE COUNT 434 a 327 c 321 g 401 t
ORIGIN
1 ggagatggtg tgtcgaccat ggaagccaaa tcacagttat ttcttaaata cttcacatta
61 tttatgaacc ttttgaatga ctgcagtgaa gttgaagatg aaagtgcgca aacaggtggc
121 aggaaacgtg gcatgtctcg gaggctggca tcactgaggc actgtacggt ccttgcaatg
181 tcaaacttac tcaatgccaa cgtagacagt ggtctcatgc actccatagg cttaggttac
241 cacaaggatc tccagacaag agctacattt atggaagttc tgacaaaaat ccttcaacaa
301 ggcacagaat ttgacacact tgcagaaaca gtattggctg atcggtttga gagattggtg
361 gaactggtca caatgatggg tgatcaagga gaactcccta tagcgatggc tctggccaat
421 gtggttcctt gttctcagtg ggatgaacta gctcgagttc tggttactct gtttgattct
481 cggcatttac tctaccaact gctctggaac atgttttcta aagaagtaga attggcagac
541 tccatgcaga ctctcttccg aggcaacagc ttggccagta aaataatgac attctgtttc
601 aaggtatatg gtgctaccta tctacaaaaa ctcctggatc ctttattacg aattgtgatc
661 acatcctctg attggcaaca tgttagcttt gaagtggatc ctaccaggtt agaaccatca
721 gagagccttg aggaaaacca gcggaacctc cttcagatga ctgaaaagtt cttccatgcc
781 atcatcagtt cctcctcaga attcccccct caacttcgaa gtgtgtgcca ctgtttatac
841 caggtggtta gccagcgttt ccctcagaac agcatcggtg cagtaggaag tgccatgttc
901 ctcagattta tcaatcctgc cattgtctca ccgtatgaag cagggatttt agataaaaag
961 ccaccaccta gaatcgaaag gggcttgaag ttaatgtcaa agatacttca gagtattgcc
1021 aatcatgttc tcttcacaaa agaagaacat atgcggcctt tcaatgattt tgtgaaaagc
1081 aactttgatg cagcacgcag gtttttcctt gatatagcat ctgattgtcc tacaagtgat
1141 gcagtaaatc atagtctttc cttcataagt gacggcaatg tgcttgcttt acatcgtcta
1201 ctctggaaca atcaggagaa aattgggcag tatctttcca gcaacaggga tcataaagct
1261 gttggaagac gaccttttga taagatggca acacttcttg catacctggg tcctccagag
1321 cacaaacctg tggcagatac acactggtcc agccttaacc ttaccagttc aaagtttgag
1381 gaatttatga ctaggcatca ggtacatgaa aaagaagaat tcaaggcttt gaaaacgtta
1441 acaccaccac cagaaccaga aacatgagct ctagagaatc cta
//