LOCUS HUMGADD45 1343 bp mRNA linear HUM 27-APR-1993
DEFINITION Human growth arrest and DNA-damage-inducible protein (gadd45) mRNA,
complete cds.
ACCESSION M60974
VERSION M60974.1
KEYWORDS DNA-damage-inducible protein; growth arrest inducible protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1343)
AUTHORS Papathanasiou,M.A., Kerr,N.C., Robbins,J.H., McBride,O.W., Alamo,I.
Jr., Barrett,S.F., Hickson,I.D. and Fornace,A.J. Jr.
TITLE Induction by ionizing radiation of the gadd45 gene in cultured
human cells: lack of mediation by protein kinase C
JOURNAL Mol. Cell. Biol. 11 (2), 1009-1016 (1991)
PUBMED 1990262
COMMENT Original source text: Human K562 leukemic cell line, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1343
/db_xref="H-InvDB:HIT000195972"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="K562"
/cell_type="leukemia"
gene 1..1343
/gene="gadd45"
CDS 284..781
/gene="gadd45"
/codon_start=1
/product="growth arrest and DNA-damage-inducible protein"
/protein_id="AAA35863.1"
/translation="MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAA
KLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELL
LLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVI
NLPER"
BASE COUNT 365 a 287 c 393 g 298 t
ORIGIN Chromosome 1 between p12 and p34.
1 ggcagtggct gggaggcagc ggcccaatta gtgtcgtgcg gcccgtggcg aggcgaggtc
61 cggggagcga gcgagcaagc aaggcgggag gggtggccgg agctgcggcg gctggcacag
121 gaggaggagc ccgggcgggc gaggggcggc cggagagcgc cagggcctga gctgccggag
181 cggcgcctgt gagtgagtgc agaaagcagg cgcccgcgcg ctagccgtgg caggagcagc
241 ccgcacgccg cgctctctcc ctgggcgacc tgcagtttgc aatatgactt tggaggaatt
301 ctcggctgga gagcagaaga ccgaaaggat ggataaggtg ggggatgccc tggaggaagt
361 gctcagcaaa gccctgagtc agcgcacgat cactgtcggg gtgtacgaag cggccaagct
421 gctcaacgtc gaccccgata acgtggtgtt gtgcctgctg gcggcggacg aggacgacga
481 cagagatgtg gctctgcaga tccacttcac cctgatccag gcgttttgct gcgagaacga
541 catcaacatc ctgcgcgtca gcaacccggg ccggctggcg gagctcctgc tcttggagac
601 cgacgctggc cccgcggcga gcgagggcgc cgagcagccc ccggacctgc actgcgtgct
661 ggtgacgaat ccacattcat ctcaatggaa ggatcctgcc ttaagtcaac ttatttgttt
721 ttgccgggaa agtcgctaca tggatcaatg ggttccagtg attaatctcc ctgaacggtg
781 atggcatctg aatgaaaata actgaaccaa attgcactga agtttttgaa atacctttgt
841 agttactcaa gcagttactc cctacactga tgcaaggatt acagaaactg atgccaaggg
901 gctgagtgag ttcaactaca tgttctgggg gcccggagat agatgacttt gcagatggaa
961 agaggtgaaa atgaagaagg aagctgtgtt gaaacagaaa aataagtcaa aaggaacaaa
1021 aattacaaag aaccatgcag gaaggaaaac tatgtattaa tttagaatgg ttgagttaca
1081 ttaaaataaa ccaaatatgt taaagtttaa gtgtgcagcc atagtttggg tatttttggt
1141 ttatatgccc tcaagtaaaa gaaaagccga aagggttaat catatttgaa aaccatattt
1201 tattgtattt tgatgagata ttaaattctc aaagttttat tataaattct actaagttat
1261 tttatgacat gaaaagttat ttatgctata aattttttga aacacaatac ctacaataaa
1321 ctggtatgaa taattgcatc att
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