LOCUS HUMKGF 3853 bp mRNA linear HUM 07-MAR-1995
DEFINITION Human keratinocyte growth factor mRNA, complete cds.
ACCESSION M60828 M25295
VERSION M60828.1
KEYWORDS fibroblast growth factor; keratinocyte growth factor; mitogen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3853)
AUTHORS Finch,P.W., Rubin,J.S., Miki,T., Ron,D. and Aaronson,S.A.
TITLE Human KGF is FGF-related with properties of a paracrine effector of
epithelial cell growth
JOURNAL Science 245 (4919), 752-755 (1989)
PUBMED 2475908
COMMENT Original source text: Human embryonic lung fibroblast cell line
M426, cDNA to mRNA, clones pCEV9-[32,49].
FEATURES Location/Qualifiers
source 1..3853
/db_xref="H-InvDB:HIT000195965"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/clone="pCEV9-32"
/cell_line="M426"
/cell_type="fibroblast"
/tissue_type="lung"
/dev_stage="embryo"
/tissue_lib="pCEV9"
gene 1..3853
/gene="FGF7"
CDS 446..1030
/gene="FGF7"
/codon_start=1
/product="keratinocyte growth factor"
/protein_id="AAA63210.1"
/db_xref="GDB:G00-131-444"
/translation="MHKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNV
NCSSPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRT
VAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNG
GEMFVALNQKGIPVRGKKTKKEQKTAHFLPMAIT"
BASE COUNT 1373 a 603 c 658 g 1219 t
ORIGIN
1 acgcgctcac acacagagag aaaatccttc tgcctgttga tttatggaaa caattatgat
61 tctgctggag aacttttcag ctgagaaata gtttgtagct acagtagaaa ggctcaagtt
121 gcaccaggca gacaacagac atggaattct tatatatcca gctgttagca acaaaacaaa
181 agtcaaatag caaacagcgt cacagcaact gaacttacta cgaactgttt ttatgaggat
241 ttatcaacag agttatttaa ggaggaatcc tgtgttgtta tcaggaacta aaaggataag
301 gctaacaatt tggaaagagc aagtactctt tcttaaatca atctacaatt cacagatagg
361 aagaggtcaa tgacctagga gtaacaatca actcaagatt cattttcatt atgttattca
421 tgaacacccg gagcactaca ctataatgca caaatggata ctgacatgga tcctgccaac
481 tttgctctac agatcatgct ttcacattat ctgtctagtg ggtactatat ctttagcttg
541 caatgacatg actccagagc aaatggctac aaatgtgaac tgttccagcc ctgagcgaca
601 cacaagaagt tatgattaca tggaaggagg ggatataaga gtgagaagac tcttctgtcg
661 aacacagtgg tacctgagga tcgataaaag aggcaaagta aaagggaccc aagagatgaa
721 gaataattac aatatcatgg aaatcaggac agtggcagtt ggaattgtgg caatcaaagg
781 ggtggaaagt gaattctatc ttgcaatgaa caaggaagga aaactctatg caaagaaaga
841 atgcaatgaa gattgtaact tcaaagaact aattctggaa aaccattaca acacatatgc
901 atcagctaaa tggacacaca acggagggga aatgtttgtt gccttaaatc aaaaggggat
961 tcctgtaaga ggaaaaaaaa cgaagaaaga acaaaaaaca gcccactttc ttcctatggc
1021 aataacttaa ttgcatatgg tatataaaga acccagttcc agcagggaga tttctttaag
1081 tggactgttt tctttcttct caaaattttc tttcctttta ttttttagta atcaagaaag
1141 gctggaaaaa ctactgaaaa actgatcaag ctggacttgt gcatttatgt ttgttttaag
1201 acactgcatt aaagaaagat ttgaaaagta tacacaaaaa tcagatttag taactaaagg
1261 ttgtaaaaaa ttgtaaaact ggttgtacaa tcatgatgtt agtaacagta atttttttct
1321 taaattaatt tacccttaag agtatgttag atttgattat ctgataatga ttatttaaat
1381 attcctatct gcttataaaa tggctgctat aataataata atacagatgt tgttatataa
1441 ggtatatcag acctacaggc ttctggcagg atttgtcaga taatcaagcc acactaacta
1501 tggaaaatga gcagcatttt aaatgctttc tagtgaaaaa ttataatcta cttaaactct
1561 aatcagaaaa aaaattctca aaaaaactat tatgaaagtc aataaaatag ataatttaac
1621 aaaagtacag gattagaaca tgcttatacc tataaataag aacaaaattt ctaatgctgc
1681 tcaagtggaa agggtattgc taaaaggatg tttccaaaaa tcttgtatat aagatagcaa
1741 cagtgattga tgataatact gtacttcatc ttacttgcca caaaataaca ttttataaat
1801 cctcaaagta aaattgagaa atctttaagt ttttttcaag taacataatc tatctttgta
1861 taattcatat ttgggaatat ggcttttaat aatgttcttc ccacaaataa tcatgctttt
1921 ttcctatggt tacagcatta aactctattt taagttgttt ttgaacttta ttgttttgtt
1981 atttaagttt atgttattta taaaaaaaaa accttaataa gctgtatctg tttcatatgc
2041 ttttaatttt aaaggaataa caaaactgtc tggctcaacg gcaagtttcc ctcccttttc
2101 tgactgacac taagtctagc acacagcact tgggccagca aatcctggaa gcagacaaaa
2161 ataagagcct gaagcaatgc ttacaataga tgtctcacac agaacaatac aaatatgtaa
2221 aaactctttc accacatatt cttgccaatt aattggatca tataagtaaa atcattacaa
2281 atataagtat ttacaggatt ttaaagttag aatatatttg aatgcatggg tagaaaatat
2341 catattttaa aactatgtat atttaaattt agtaattttc taatctctag aaatctctgc
2401 tgttcaaaag gtggcagcac tgaaagttgt tttcctgtta gatggcaaga gcacaatgcc
2461 caaaatagaa gatgcagtta agaataaggg gccctgaatg tcatgaaggc ttgaggtcag
2521 cctacagata acaggattat tacaaggatg aatttccact tcaaaagtct ttcattggca
2581 gatcttggta gcactttata tgttcaccaa tgggaggtca atatttatct aatttaaaag
2641 gtatgctaac cactgtggtt ttaatttcaa aatatttgtc attcaagtcc ctttacataa
2701 atagtatttg gtaatacatt tatagatgag agttatatga aaaggctagg tcaacaaaaa
2761 caatagattc atttaatttt cctgtggttg acctatacga ccaggatgta gaaaactaga
2821 aagaactgcc cttcctcaga tatactcttg ggagagagca tgaatggtat tctgaactat
2881 cacctgattc aaggactttg ctagctaggt tttgaggtca ggcttcagta actgtagtct
2941 tgtgagcata ttgagggcag aggaggactt agtttttcat atgtgtttcc ttagtgccta
3001 gcagactatc tgttcataat cagttttcag tgtgaattca ctgaatgttt atagacaaaa
3061 gaaaatacac actaaaacta atcttcattt taaaagggta aaacatgact atacagaaat
3121 ttaaatagaa atagtgtata tacatataaa atacaagcta tgttaggacc aaatgctctt
3181 tgtctatgga gttatacttc catcaaatta catagcaatg ctgaattagg caaaaccaac
3241 atttagtggt aaatccattc ctggtagtat aagtcaccta aaaaagactt ctagaaatat
3301 gtactttaat tatttgtttt tctcctattt ttaaatttat tatgcaaatt ttagaaaata
3361 aaatttgctc tagttacaca cctttagaat tctagaatat taaaactgta aggggcctcc
3421 atccctctta ctcatttgta gtctaggaaa ttgagatttt gatacaccta aggtcacgca
3481 gctgggtaga tatacagctg tcacaagagt ctagatcagt tagcacatgc tttctactct
3541 tcgattatta gtattattag ctaatggtct ttggcatgtt tttgtttttt atttctgttg
3601 agatatagcc tttacatttg tacacaaatg tgactatgtc ttggcaatgc acttcataca
3661 caatgactaa tctatactgt gatgatttga ctcaaaagga gaaaagaaat tatgtagttt
3721 tcaattctga ttcctattca ccttttgttt atgaatggaa agctttgtgc aaaatataca
3781 tataagcaga gtaagccttt taaaaatgtt ctttgaaaga taaaattaaa tacatgagtt
3841 tctaacaatt aga
//