LOCUS HUMP70S6KA 2346 bp mRNA linear HUM 27-APR-1993
DEFINITION Human p70 ribosomal S6 kinase alpha-I mRNA, complete cds.
ACCESSION M60724
VERSION M60724.1
KEYWORDS p70 ribosomal S6 kinase alpha-I.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2346)
AUTHORS Grove,J.R., Banerjee,P., Balasubramanyam,A., Coffer,P.J.,
Price,D.J., Avruch,J. and Woodgett,J.R.
TITLE Cloning and expression of two human p70 S6 kinase polypeptides
differing only at their amino termini
JOURNAL Mol. Cell. Biol. 11 (11), 5541-5550 (1991)
PUBMED 1922062
COMMENT Original source text: Human liver hepatoma, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2346
/db_xref="H-InvDB:HIT000195958"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="hepatoma"
/tissue_type="liver"
CDS 28..1605
/codon_start=1
/product="p70 ribosomal S6 kinase alpha-I"
/protein_id="AAA36410.1"
/translation="MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDEL
EEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGY
GKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIY
AFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRD
LKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDW
WSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAAS
RLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPV
DSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVK
FSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKK
QAFPMISKRPEHLRMNL"
BASE COUNT 750 a 453 c 558 g 585 t
ORIGIN
1 gcacgaggct gcggcgggtc cgggcccatg aggcgacgaa ggaggcggga cggcttttac
61 ccagccccgg acttccgaga cagggaagct gaggacatgg caggagtgtt tgacatagac
121 ctggaccagc cagaggacgc gggctctgag gatgagctgg aggagggggg tcagttaaat
181 gaaagcatgg accatggggg agttggacca tatgaacttg gcatggaaca ttgtgagaaa
241 tttgaaatct cagaaactag tgtgaacaga gggccagaaa aaatcagacc agaatgtttt
301 gagctacttc gggtacttgg taaagggggc tatggaaagg tttttcaagt acgaaaagta
361 acaggagcaa atactgggaa aatatttgcc atgaaggtgc ttaaaaaggc aatgatagta
421 agaaatgcta aagatacagc tcatacaaaa gcagaacgga atattctgga ggaagtaaag
481 catcccttca tcgtggattt aatttatgcc tttcagactg gtggaaaact ctacctcatc
541 cttgagtatc tcagtggagg agaactattt atgcagttag aaagagaggg aatatttatg
601 gaagacactg cctgctttta cttggcagaa atctccatgg ctttggggca tttacatcaa
661 aaggggatca tctacagaga cctgaagccg gagaatatca tgcttaatca ccaaggtcat
721 gtgaaactaa cagactttgg actatgcaaa gaatctattc atgatggaac agtcacacac
781 acattttgtg gaacaataga atacatggcc cctgaaatct tgatgagaag tggccacaat
841 cgtgctgtgg attggtggag tttgggagca ttaatgtatg acatgctgac tggagcaccc
901 ccattcactg gggagaatag aaagaaaaca attgacaaaa tcctcaaatg taaactcaat
961 ttgcctccct acctcacaca agaagccaga gatctgctta aaaagctgct gaaaagaaat
1021 gctgcttctc gtctgggagc tggtcctggg gacgctggag aagttcaagc tcatccattc
1081 tttagacaca ttaactggga agaacttctg gctcgaaagg tggagccccc ctttaaacct
1141 ctgttgcaat ctgaagagga tgtaagtcag tttgattcca agtttacacg tcagacacct
1201 gtcgacagcc cagatgactc aactctcagt gaaagtgcca atcaggtctt tctgggtttt
1261 acatatgtgg ctccatctgt acttgaaagt gtgaaagaaa agttttcctt tgaaccaaaa
1321 atccgatcac ctcgaagatt tattggcagc ccacgaacac ctgtcagccc agtcaaattt
1381 tctcctgggg atttctgggg aagaggtgct tcggccagca cagcaaatcc tcagacacct
1441 gtggaatacc caatggaaac aagtggcata gagcagatgg atgtgacaat gagtggggaa
1501 gcatcggcac cacttccaat acgacagccg aactctgggc catacaaaaa acaagctttt
1561 cccatgatct ccaaacggcc agagcacctg cgtatgaatc tatgacagag caatgctttt
1621 aatgaattta aggcaaaaag gtggagaggg agatgtgtga gcatcctgca aggtgaaaca
1681 agactcaaaa tgacagtttc agagagtcaa tgtcattaca tagaacactt cggacacagg
1741 aaaaataaac gtggatttta aaaaatcaat caatggtgca aaaaaaaact taaagcaaaa
1801 tagtattgct gaactcttag gcacatcaat taattgattc ctcgcgacat ctttctcaac
1861 cttatcaagg attttcatgt tgatgactcg aaactgacag tattaagggt aggatgttgc
1921 tctgaatcac tgtgagtctg atgtgtgaag aagggtatcc tttcattagg caagtacaaa
1981 ttgcctataa tacttgcaac taaggacaaa ttagcatgca agcttggtca aacttttccc
2041 aggcaaaatg ggaaggcaaa gacaaaagaa acttaccaat tgatgtttta cgtgcaaaca
2101 acctgaatct tttttttata taaatatata tttttcaaat agatttttga ttcagctcat
2161 tatgaaaaac atcccaaact ttaaaatgcg aaattattgg ttggtgtgaa gaaagccaga
2221 caacttctgt ttcttctctt ggtgaaataa taaaatgcaa atgaatcatt gttaacacag
2281 ctgtggctcg tttgagggat tggggtggac ctggggttta ttttcagtaa cccagctgcg
2341 gagcct
//