LOCUS HUMNFONE 2012 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human neurofibromatosis protein type 1 (NF1) mRNA, 3' end.
ACCESSION M60496 M49193
VERSION M60496.1
KEYWORDS neurofibromatosis protein type 1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2012)
AUTHORS Wallace,M.R., Marchuk,D.A., Andersen,L.B., Letcher,R., Odeh,H.,
Saulino,A.M., Fountain,J., Brereton,A., Nicholson,J., Mitchell,A.,
Brownstein,B.H. and Collins,F.S.
TITLE Type 1 neurofibromatosis gene: identification of a large transcript
disrupted in three NF1 patients
JOURNAL Science 249 (4965), 181-186 (1990)
PUBMED 2134734
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2012
/db_xref="H-InvDB:HIT000195944"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2012
/gene="NF1"
CDS <1..1833
/gene="NF1"
/codon_start=1
/product="neurofibromatosis protein type 1"
/protein_id="AAA59928.1"
/translation="TELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSK
ALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLY
SAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFA
LVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSE
EVRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPSYRTLKETQPWSSPKGSEGYLA
ATYPTVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGI
TTPPKMRRVAETDYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLT
VLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLN
PIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDA
LIDTYLPGIDEETSEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGID
KENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV"
BASE COUNT 589 a 483 c 389 g 551 t
ORIGIN chromosome 17q11.2.
1 acagaactag ctcaaagatt tgcattccaa tataatccat ccctgcaacc aagagctctt
61 gttgtctttg ggtgtattag caaacgagtg tctcatgggc agataaagca gataatccgt
121 attcttagca aggcacttga gagttgctta aaaggacctg acacttacaa cagtcaagtt
181 ctgatagaag ctacagtaat agcactaacc aaattacagc cacttcttaa taaggactcg
241 cctctgcaca aagccctctt ttgggtagct gtggctgtgc tgcagcttga tgaggtcaac
301 ttgtattcag caggtaccgc acttcttgaa caaaacctgc atactttaga tagtctccgt
361 atattcaatg acaagagtcc agaggaagta tttatggcaa tccggaatcc tctggagtgg
421 cactgcaagc aaatggatca ttttgttgga ctcaatttca actctaactt taactttgca
481 ttggttggac accttttaaa agggtacagg catccttcac ctgctattgt tgcaagaaca
541 gtcagaattt tacatacact actaactctg gttaacaaac acagaaattg tgacaaattt
601 gaagtgaata cacagagcgt ggcctactta gcagctttac ttacagtgtc tgaagaagtt
661 cgaagtcgct gcagcctaaa acatagaaag tcacttcttc ttactgatat ttcaatggaa
721 aatgttccta tggatacata tcccattcat catggtgacc cttcctatag gacactaaag
781 gagactcagc catggtcctc tcccaaaggt tctgaaggat accttgcagc cacctatcca
841 actgtcggcc agaccagtcc ccgagccagg aaatccatga gcctggacat ggggcaacct
901 tctcaggcca acactaagaa gttgcttgga acaaggaaaa gttttgatca cttgatatca
961 gacacaaagg ctcctaaaag gcaagaaatg gaatcaggga tcacaacacc ccccaaaatg
1021 aggagagtag cagaaactga ttatgaaatg gaaactcaga ggatttcctc atcacaacag
1081 cacccacatt tacgtaaagt ttcagtgtct gaatcaaatg ttctcttgga tgaagaagta
1141 cttactgatc cgaagatcca ggcgctgctt cttactgttc tagctacact ggtaaaatat
1201 accacagatg agtttgatca acgaattctt tatgaatact tagcagaggc cagtgttgtg
1261 tttcccaaag tctttcctgt tgtgcataat ttgttggact ctaagatcaa caccctgtta
1321 tcattgtgcc aagatccaaa tttgttaaat ccaatccatg gaattgtgca gagtgtggtg
1381 taccatgaag aatccccacc acaataccaa acatcttacc tgcaaagttt tggttttaat
1441 ggcttgtggc ggtttgcagg accgttttca aagcaaacac aaattccaga ctatgctgag
1501 cttattgtta agtttcttga tgccttgatt gacacgtacc tgcctggaat tgatgaagaa
1561 accagtgaag aatccctcct gactcccaca tctccttacc ctcctgcact gcagagccag
1621 cttagtatca ctgccaacct taacctttct aattccatga cctcacttgc aacttcccag
1681 cattccccag gaatcgacaa ggagaacgtt gaactctccc ctaccactgg ccactgtaac
1741 agtggacgaa ctcgccacgg atccgcaagc caagtgcaga agcaaagaag cgctggcagt
1801 ttcaaacgta atagcattaa gaagatcgtg tgaagcttgc ttgctttctt ttttaaaatc
1861 aacttaacat gggctcttca ctagtgaccc cttccctgtc cttgcccttt ccccccatgt
1921 tgtaatgctg cacttcctgt tttataatga acccatccgg tttgccatgt tgccagatga
1981 tcaactcttc gaagccttgc ctaaatttaa tg
//