LOCUS HUMEP2AA 9318 bp DNA linear HUM 04-DEC-1997
DEFINITION Homo sapiens HIV-EP2/Schnurri-2 gene, complete cds.
ACCESSION M60119
VERSION M60119.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1603 to 9318)
AUTHORS Nomura,N., Zhao,M.J., Nagase,T., Maekawa,T., Ishizaki,R., Tabata,S.
and Ishii,S.
TITLE HIV-EP2, a new member of the gene family encoding the human
immunodeficiency virus type 1 enhancer-binding protein. Comparison
with HIV-EP1/PRDII-BF1/MBP-1
JOURNAL J. Biol. Chem. 266 (13), 8590-8594 (1991)
PUBMED 2022670
REFERENCE 2 (bases 1 to 9318)
AUTHORS Goto-Mandeville,R., Tashiro,S., Harada,J., Takagi,T., Sano,Y.,
Nomura,T.N., Emi,M., Miyazono,K. and Ishii,S.
TITLE Human Schnurri-2 antagonizes BMP and TGF-b signalling by anchoring
Smads in cytoplasm
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 9318)
AUTHORS Nomura,N.
TITLE Direct Submission
JOURNAL Submitted (16-MAY-1991) Lab. of Gene Structure I, Kazusa DNA
Research Institute, 1532-3 Yana, Kisarazu, Chiba 292, Japan
REFERENCE 4 (bases 1 to 9318)
AUTHORS Nomura,N.
TITLE Direct Submission
JOURNAL Submitted (04-DEC-1997) Lab. of Gene Structure I, Kazusa DNA
Research Institute, 1532-3 Yana, Kisarazu, Chiba 292, Japan
REMARK Sequence update by submitter
COMMENT On Dec 4, 1997 this sequence version replaced gi:182119.
FEATURES Location/Qualifiers
source 1..9318
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/cell_type="T-cell"
/tissue_type="umbilical vein"
gene 2178..7679
/gene="HIV-EP2/Schnurri-2"
CDS 2178..7679
/gene="HIV-EP2/Schnurri-2"
/codon_start=1
/protein_id="AAB88218.1"
/translation="MLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQN
YRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSS
IVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLV
SEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAP
SPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVP
EIRVTEEPDKPEKEKEAQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADM
EHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETSKLSALPKQDEFGKHSE
FLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPAEVPEVRSKSFDYGNLSHAPVSG
AAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHH
GPPAVLPPLQQEDPGKQVAGPCPPLSSGPLHLAQPQIMHMDSQESLRNPLIQPTSYMT
SKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQH
PQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLP
KFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSI
SQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKAPQ
TLPLGLESSIPLCLPSTSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQI
VEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDGLQSGSSSFSSLSPSSSQDYP
SVSPSSREPFPPSKEMLSGSRAPLPGQKSSGPSESKESSDELDIDETASDMSMSPQSS
SLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRT
TTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKIT
AEIYTLAAMHRPGTGKLTSSSAWKQFTQMKPDASFLFGSKLERKLVGNILKERGKGDI
HGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKH
IRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAEN
LEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDFDDQGDLTPKTRS
RSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIRVTQLMTPSDSCE
DTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSPG
YDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSP
RRHLSPRRPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAE
PIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVR
APIPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQ
HEKRGPHALQSSGPPSTPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIA
TEEAALLGPDQPARVQEPHQNPLGSAHVSIRHFSRPEPGQPCTSATHPDLHDGEKDNF
GTSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH"
variation 7254
/gene="HIV-EP2/Schnurri-2"
BASE COUNT 2667 a 2191 c 2161 g 2299 t
ORIGIN
1 gctggcaaaa ttcctagact attcatcatc ccaatttcat cctagttgaa aattttcaaa
61 tgccataaga aatctttata gatttgcact tagcttttgg atggacgttt ctacaatgga
121 gagaactgtg ttatagccct ggtccaagga cattactagc taatgcccat cgactgtggt
181 gtgcgtgtgg aaggttccaa agagaaggag caatcagcaa gtttgcagac accctggaac
241 atggaagcaa ccaagcttta agaagcacag ctttggagac actccatgag tctgcactgc
301 tttcagggga actagcactt aagaccttgt gtaacaaaat ggacactggg gacacagctc
361 taggacaaaa agctacctca aggtctggag aaactgataa agcatcaggt agatggagac
421 aggaacaatc agctgttatt aagatgagca cttttggcag tcatgaagga cagcggcaac
481 cacaaataga gcctgagcaa atcggaaaca cagcatcagc acaactgttt ggttctggga
541 aactggcctc ccctagtgaa gtggtgcagc aagtcgcaga gaagcaatat ccaccgcatc
601 gtccgagtcc ttactcatgc caacactcac tctctttccc tcagcactca ttgccacagg
661 gggtcatgca cagcaccaag ccacatcaga gcctcgaagg tcctccgtgg cttttccctg
721 gccctttgcc atccgttgcc tctgaggact tatttccttt tcctatacat ggccacagtg
781 gtggttatcc tagaaaaaag atttcaagtc tgaaccctgc ttatagccaa tactcccaga
841 aaagtattga acaggcagaa gaggctcaca agaaagagca caaacccaaa aagcctggca
901 agtacatttg cccttactgc agcagagcgt gtgccaaacc tagtgtactg aaaaaacaca
961 tcaggtccca tactggggag cggccatatc catgtatacc ttgtggtttc tctttcaaga
1021 caaagagcaa tttgtacaag cacaggaagt cacatgccca tgcaattaag gcaggattag
1081 tacctttcac agagtcagct gtatctaaat tggacctaga ggctggtttt attgatgtag
1141 aagcagaaat acattcagat ggtgaacaga gtacagacac agatgaggag agttctttat
1201 ttgccgaggc ttctgacaaa atgagtcctg gtccacccat cccactggac attgccagca
1261 gaggcggcta tcatgggtca ttggaagaat cattgggagg tccaatgaag gtgccgattt
1321 tgattatccc taaaagtggg attcctctcc ctaatgaaag ctctcagtat attggccctg
1381 atatgctacc aaatccatct ttaaatacta aggctgatga ttcgcacaca gtcaaacaga
1441 aacttgcact aagactgtca gagaaaaaag gacaagattc tgagccatcg ctcaaccttc
1501 tgagcccgca cagtaaagga agcactgatt ctggttactt ttctcgctca gaaagtgctg
1561 agcagcaaat aagccctccc aacacaaatg caaagtctta tgaagaaatc atctttggaa
1621 aatactgtcg gcttagtccg agaaatgcac tcagtgttac aaccacaagt caggagcgtg
1681 ccgcaatggg taggaagggc ataatggaac cattacctca cgttaacacc aggttagatg
1741 tcaagatgtt tgaagatcct gtttcacagc tgatcccaag caagggagat gtcgacccca
1801 gtcaaacgag catgctgaaa tccactaagt tcaacagtga gtccagacaa ccccagatta
1861 ttccatcatc tatcaggaac gaaggaaaac tttatccagc aaacttccaa ggcagcaacc
1921 cggttctctt agaagctcct gtagactctt caccccttat tagaagcaac tcagtgccaa
1981 cttcttcagc aactaatcta actattcctc cttctttgag aggaagtcac tcatttgatg
2041 aaaggatgac tggttccgac gatgtattct atccagggac cgtgggcata ccccctcagc
2101 gcatgctaag aagacaagcg gcatttgagc tgccttcggt acaggagggc cacgtggaag
2161 tcgagcacca tggcaggatg ttgaagggta tcagcagttc atccctgaag gaaaagaaat
2221 tgtctcctgg ggacagggtt gggtatgact atgatgtctg tcggaaaccc tataagaagt
2281 gggaggactc tgaaacacca aagcaaaact acagggacat ttcctgcttg agttctttaa
2341 agcatggtgg agaatatttc atggatcccg tggtgccatt gcagggagta ccaagcatgt
2401 ttggaactac ctgtgaaaac aggaaacgcc ggaaagagaa gagcgtaggg gatgaagagg
2461 acacgcccat gatctgcagc agcattgtaa gcactcctgt gggcatcatg gcttccgatt
2521 atgaccccaa actgcagatg caggaaggag tcaggagtgg atttgccatg gctggacacg
2581 aaaacctttc tcatggtcac acggaacgct ttgacccatg tcggccccaa ctgcagcctg
2641 gaagtccatc tcttgtgtca gaggagtcac cttcagccat tgattcagac aagatgtcag
2701 acctaggggg caggaaacct cctggaaatg tgatttctgt gattcagcac accaactcac
2761 tgagccgacc caattcattt gaaaggtctg agtcagccga acttgtggct tgcacacagg
2821 ataaagcccc ttccccttca gagacttgtg acagtgagat ttcagaagcc ccagtgagtc
2881 ctgagtgggc tccacctggg gatggtgcag aaagtggggg gaaaccctct ccatctcagc
2941 aggtgcagca gcagtcctat cacacacagc ccaggctagt tcggcaacac aacatccagg
3001 ttcctgagat tcgagtgacc gaggagcctg ataaacctga gaaggagaag gaagcccaga
3061 gcaaagagcc agagaagcct gtggaagaat ttcagtggcc ccagagaagt gagacccttt
3121 cccagctccc cgcggagaag ttgccaccca aaaagaagcg tctgcgactt gcagatatgg
3181 agcactcctc aggggagtcc agctttgaat ccacaggcac aggcctctcc cgcagcccca
3241 gccaagaaag caacttgtcc cacagctcca gtttctccat gtcttttgaa agagaagaaa
3301 ccagtaagct ttctgcactt cctaagcagg atgagtttgg gaagcattca gagtttctga
3361 ctgtccctgc tggttcatac tcattgtctg tcccaggcca tcaccaccag aaagagatgc
3421 gacgctgctc atcagagcag atgccttgtc ctcacccagc ggaagtccca gaagttcgga
3481 gcaaatcatt tgattatggg aatctgtccc atgctcctgt gtcgggagca gcagcctcca
3541 cggtatcacc gtccagggag aggaagaaat gctttctggt gcggcaagct tccttcagtg
3601 gctccccaga aatctcccag ggcgaggttg gcatggatca gagcgtgaag caagagcagc
3661 tggagcacct gcatgctggc ctccggtccg ggtggcacca tggcccgcct gctgtgctgc
3721 ctcctcttca gcaagaggac ccagggaagc aggtggcggg tccttgtccc ccgctgagct
3781 cggggccact gcacctggcc cagccacaga tcatgcacat ggacagtcag gaatctttga
3841 gaaatccctt gatccaacca acatcctata tgacaagcaa gcacttacct gaacagccac
3901 acttatttcc acatcaagag acaattccat tttctccaat ccagaatgcc ttgtttcagt
3961 ttcagtatcc tacagtttgt atggttcatt taccagctca gcagcctccc tggtggcagg
4021 cacatttccc acatcccttt gctcagcacc ctcagaagag ctatggcaag ccctcttttc
4081 agacagaaat ccattcgagc tatcccttag agcatgtggc agagcacact ggaaagaaac
4141 ctgctgagta tgcacacacg aaagagcaga cctacccatg ttattcagga gcatcagggc
4201 tacacccaaa gaaccttctt ccaaagtttc catcagacca gagcagtaag tcaactgaaa
4261 cgccctctga gcaggttctt caagaagatt ttgcctcggc aaatgctggg tctttgcagt
4321 ccctcccagg aacagtggtt cctgttcgga tccagacgca cgtaccatcc tatggaagtg
4381 tcatgtacac aagcatttct cagatacttg ggcagaatag ccctgccatt gtcatatgca
4441 aagtcgatga gaatatgacc caaaggacac tggtcaccaa cgcagccatg caagggatag
4501 gattcaacat tgcccaggtg ctggggcagc atgcgggctt ggagaagtac cccatttgga
4561 aagcacctca gactttgccc ctcggcttag aatcctccat ccccttgtgt ttaccttcca
4621 cctctgacag cgtggccacc ctgggaggta gcaagcgaat gctttctcca gccagtagct
4681 tggagctctt catggaaacc aagcagcaga aaagggtcaa agaagaaaag atgtacggac
4741 agattgtgga ggagcttagt gctgtggagc tgaccaactc agacatcaaa aaggacctct
4801 cccgccccca gaaaccccag ctggttcgac aaggatgtgc ttctgagcca aaagatggct
4861 tgcagtcagg gtcatcttcc ttctcctcgc tgtcgccctc ctcatctcaa gactatcctt
4921 ctgttagccc gtcttccagg gagccattcc cgcccagcaa ggagatgctt tccggttccc
4981 gggcaccact tccggggcag aagtccagtg ggccttctga aagcaaagaa tcttcagatg
5041 aattagatat cgatgagacg gcatcggaca tgagcatgag cccacagagt tcttcattac
5101 cagcaggaga tggtcagctg gaagaggaag ggaagggcca caagcggcct gttggcatgc
5161 tggtccgcat ggcctctgcc cccagcggga acgtggcaga ctcaactctt cttctcacgg
5221 acatggcaga tttccagcag attcttcagt tccccagtct gcggacaaca actactgtga
5281 gttggtgctt cttgaattat acaaaaccca attatgtgca acaggccacc ttcaaatcct
5341 cggtttatgc ttcatggtgc attagttcct gtaatccaaa cccatcagga ttgaacacca
5401 agaccacgct ggctcttctg aggtccaagc aaaaaatcac tgcagaaatt tatactctgg
5461 ctgctatgca taggcctgga accggcaagc ttacatcatc aagtgcttgg aagcagttta
5521 ctcagatgaa acctgatgcg tcctttttat ttggcagcaa actagaaagg aaactagtgg
5581 gaaatatctt aaaggaaaga gggaaaggag atattcatgg agataaagat attggatcca
5641 aacaaactga gccaatccga attaaaatat ttgaaggagg gtacaaatcg aatgaagatt
5701 atgtatatgt cagaggacgt ggccggggaa agtacatttg tgaagaatgt gggattcgct
5761 gtaagaagcc aagcatgctc aaaaaacaca tccgtaccca tactgatgtt cggccttatg
5821 tatgcaagtt atgtaacttt gccttcaaaa cgaaaggaaa cctaacgaag catatgaaat
5881 ctaaagcaca catgaaaaaa tgcctggaat tgggagtctc aatgacatcg gtggatgata
5941 cagaaactga ggaagcagaa aatttggaag atttgcacaa agcagcagag aagcatagca
6001 tgtccagcat ttcaactgat catcagttct ccgatgctga ggaatcagat ggtgaggatg
6061 gagatgataa tgatgatgat gatgaagatg aagatgactt tgacgaccag ggagatttaa
6121 caccaaaaac aagatcaaga agcaccagtc ctcagcctcc tagattctcc tccttgcctg
6181 tgaatgttgg cgccgtaccc cacggggttc cttcagatag ttccctggga cattcttcgt
6241 tgatcagcta tttggttact ttgccaagta ttcgagttac tcagcttatg acacccagtg
6301 attcatgtga agatacccag atgacagaat accagaggct attccagagc aaaagtacgg
6361 actcagaacc agacaaagac agattggaca tacctagttg tatggatgag gagtgcatgc
6421 taccttcaga gccaagctcc tctcccaggg acttctcacc ctcaagccac cattcctctc
6481 caggatatga ttcttcaccc tgtcgagata attcaccaaa gaggtatctg atacccaaag
6541 gagatttatc tcccaggaga catttatcac ctaggagaga tctgtcaccc atgagacatc
6601 tttcaccaag aaaggaagct gcattgagaa gagagatgtc ccaaagagat gtttcaccaa
6661 gaaggcattt gtctccaagg aggccagtgt ctcctgggaa agatatcaca gcaagaagag
6721 acctctcccc tagaagagag agaagataca tgaccacaat aagagcgcca tctcccagaa
6781 gggctttata ccataaccca ccattgtcca tgggacagta tttgcaagca gagccaattg
6841 tattggggcc tcctaattta agaagaggat tacctcaggt tccttacttc agtctctatg
6901 gagaccaaga aggtgcttat gaacatccag gctccagcct tttccctgag ggtcctaatg
6961 actatgtctt cagtcatctt ccactccact ctcagcaaca agtgcgagcc cctatcccca
7021 tggtgcccgt tggtgggatc cagatggttc actccatgcc gccagccctt tccagtttac
7081 atccttcacc cacattgccc ctgccaatgg agggctttga ggagaagaaa ggcgcgtcag
7141 gggagtcctt ctccaaggac ccctatgtgc tttctaagca gcatgagaag cgaggtcctc
7201 acgctttgca gtcatctggt ccgcctagca ctccctcctc tcctcggctg ttgatgaaac
7261 agagcacttc ggaagacagc ctaaacgcaa cagagcggga acaggaggaa aatatacaga
7321 cttgtacaaa agccattgcc tctctccgga ttgccacgga agaggcagct ctgctcgggc
7381 cagatcagcc agcgcgggtg caggagcccc accagaaccc cctgggaagt gcacatgtta
7441 gcattagaca ctttagtaga cctgagccag gtcagccctg tacctcagcc acccaccctg
7501 acttgcatga tggtgaaaag gacaattttg gtacatcaca gactccatta gctcactcca
7561 cgttttacag caagagttgt gtggatgaca agcagttgga ctttcacagc agcaaggaat
7621 tatcttcaag cacagaggaa agcaaagatc cttcatcaga aaagagtcag ctacattgat
7681 ctatgatgca tggagacttt catttccaca ttttcccatt tttttgtttt tgtttttcta
7741 gaaatggagg taatccagtt tatagcatgc ctgtcctaag ttacagtagt ttgctattat
7801 atatactttt gttatatcaa aagaattagg taaattaaca agtcatcatg agcctgacca
7861 aaacaaaatt tgaaattaac ctattgggtc tggtactttt aaaattgtac agatgtttgt
7921 gccttttctt tactttgctt atattcttat aagcattttt tagcagtaat ttgtacatat
7981 tttagaattt gtgtatctgc tttgtaataa atgtaatttc tttccttttt tggacacttg
8041 gatctaaatg atgtaaagca aaacagcatc aatatatatg tgaggttgca ctaaaacata
8101 tttttatatg attaaaactg aacagctttt atgtacagct ctgattctgt aatactaata
8161 tttatttact ttgtttcata aattgtacat tttttcttaa tgttgtggat tgcttttcta
8221 tgtgaagcat gggatttact gttgcgtaac tagaacaaaa atgtacattg taaacaagat
8281 atttaaacta gagtatctta ttctgcactt atgcattagt taaaaaaaga taaaggatgt
8341 atcagtcagt tcttaactct tgtatatttt tttgtctctt gtttgctgga ttgactataa
8401 cttaagtgct gattgtgatt ttaaaatgat agtaccgtaa agcattaaag taaacaatgt
8461 gctattgtga gttttttcaa agctttataa atcagttata aataatatta aaagtatttg
8521 gtcttatgtg aacatgttga tctatatact catctaaaaa tatgggaaaa cattccaccc
8581 catgtaaata tgtacaagtg catcactggt acaattttat gtaactcagt tggacactag
8641 gttgccacag acctatgcta ggtgtcttta aaaaattaag gtgacaaagc acatgggact
8701 gtgtagagct tggttatcgg ccggcccggt ggcttggcag gcagtgctgt gcgctgctca
8761 tggagaagac ctgggcttag caatctcctt agttcttgct acacaggatg gtgactggaa
8821 ctaaggctac acagagggtc gcacttggac tctgagggtt gggtgtggaa gggggaaaag
8881 gggatggaga cctgctcccc agctcttcct gtcagccggt ttacatggga acagggttaa
8941 catctgtgtt aggggaggtc accttaccct ttttcatagg ggaagagtgt cacactcctg
9001 gctatctcag ggggaatggg gaaaagaatc tttcaagggc aaagaactcg tgggaggatg
9061 tctgttgtat gtaatactca caatggcttt tggttagtgt tgaaggtggg aagagcattt
9121 gtaggtccag aagagtgaaa gagagggagg ggtgcagcaa catgtgcaca ggcacgcaca
9181 tgtgtgcacg cacacataca atctgggtta tctttgtgct atatagtgga ttataattct
9241 gtgaaaccaa gtttgtatat tgaattacat taaggagtgt tctttaaaaa gagaaataaa
9301 tatacaatta catgcttg
//