LOCUS HUMHCPB 2365 bp mRNA linear HUM 14-FEB-1996
DEFINITION Human histidine-rich calcium binding protein (HRC) mRNA, complete
cds.
ACCESSION M60052 J04784 J04785 J04786
VERSION M60052.1
KEYWORDS histidine-rich calcium binding protein; luminal sarcoplasmic
reticulum protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2365)
AUTHORS Hofmann,S.L., Topham,M., Hsieh,C.L. and Francke,U.
TITLE cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum
protein, and localization of the gene to human chromosome 19 and
mouse chromosome 7
JOURNAL Genomics 9 (4), 656-669 (1991)
PUBMED 2037293
COMMENT Original source text: Homo sapiens adult skeletal muscle cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..2365
/db_xref="H-InvDB:HIT000195918"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19q13.2-q13.3"
/tissue_type="skeletal muscle"
/dev_stage="adult"
gene 1..2365
/gene="HRC"
CDS 171..2270
/gene="HRC"
/codon_start=1
/product="histidine-rich calcium binding protein"
/protein_id="AAA88071.1"
/db_xref="GDB:G00-126-369"
/translation="MGHHRPWLHASVLWAGVASLLLPPAMTQQLRGDGLGFRNRNNST
GVAGLSEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHL
LPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSH
QDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRG
HGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH
GIEEDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSG
EHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVA
SHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEET
GHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKG
THHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDH
SEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQPG
SLCGYCSFCNRCTECESCHCDEENMGEHCDQCQHCQFCYLCPLVCETVCAPGSYVDYF
SSSLYQALADMLETPEP"
sig_peptide 171..254
/gene="HRC"
/note="G00-126-369"
mat_peptide 255..2267
/gene="HRC"
/product="histidine-rich calcium binding protein"
/note="G00-126-369"
BASE COUNT 682 a 606 c 731 g 346 t
ORIGIN human chromosome 19q13.3 and mouse chromosome 7.
1 gaggggtgtc cagagccagg cagcaaggac cagaggaagg tggacagaga ccgaaaggac
61 aaaggagaga cacagagaaa aaaagagacc aaccccaaag ggacaaagac cccaacgttt
121 gtccacattg ccgcagaggc agctggagcc agtgctgcct gtccgtcccc atgggccacc
181 ataggccatg gctgcacgct tctgtcctct gggctggggt ggccagcctg ctcctccccc
241 cggccatgac ccagcagctc agaggggatg ggctaggctt cagaaaccgg aacaacagca
301 ctggagtcgc cgggctctcc gaggaggcat cagcagagct tcgccaccac ctccacagcc
361 ctagagacca tccagatgag aacaaggatg tttccacaga gaatgggcat catttctgga
421 gccacccaga ccgtgaaaag gaggatgaag atgtctccaa ggaatatggg cacctactcc
481 caggccacag gtcccaagac cacaaagtcg gagatgaggg tgtctcaggt gaggaggtct
541 ttgcagagca tggtgggcag gcccgtgggc acagaggcca cgggagtgaa gacacggaag
601 actcagctga gcacaggcac cacctcccca gccacaggag ccacagccat caagacgagg
661 atgaggatga agttgtgtcc agtgagcatc accatcatat cctcaggcat ggacaccgag
721 gccatgatgg ggaagatgat gaaggagaag aggaggagga ggaggaggag gaggaagagg
781 aggcctccac tgagtatgga caccaggccc acaggcaccg aggccatggg agtgaagagg
841 atgaggatgt ctcagatgga caccatcatc atggccccag ccacaggcac caaggccatg
901 aagaagatga cgatgatgat gatgatgatg atgatgatga tgatgatgat gatgtctcca
961 ttgaatatag acaccaggct cacaggcacc aaggccacgg gattgaagag gatgaagatg
1021 tctcagatgg acaccatcat cgcgacccca gccacaggca ccgaagccat gaagaagatg
1081 acaatgatga tgatgatgtc tccactgagt atggacacca ggcccacagg caccaagacc
1141 acagaaagga agaggttgag gctgtctcag gtgaacacca ccatcatgtc cctgaccaca
1201 ggcaccaagg ccacagagac gaggaagaag atgaggatgt gtccactgaa cgttggcacc
1261 agggtcccca acatgtccac catggccttg tagatgagga agaggaagaa gaggagatca
1321 cagtccagtt tggccactat gttgcaagcc accaacctcg aggccacaag agtgatgaag
1381 aggacttcca agatgagtat aaaacagaag tccctcacca tcaccaccac agagtcccca
1441 gggaggaaga tgaggaggtc tctgctgagc ttggccacca ggcccccagc cacaggcaaa
1501 gccaccaaga tgaagaaact ggccatggtc aaagagggtc catcaaagag atgagccatc
1561 accccccagg acacacagtg gtcaaggata gaagccattt gaggaaggat gattctgagg
1621 aggaaaagga gaaggaagag gaccccggct cccatgagga agacgatgaa agttcagagc
1681 agggagagaa aggcacccat catggcagcc gggaccagga agatgaggag gatgaggagg
1741 aaggtcatgg cctcagcctg aaccaggagg aggaagaaga ggaagacaag gaggaggagg
1801 aggaggaaga agacgaggag aggagggaag agagggctga ggttggggcc ccactgagcc
1861 cagaccacag cgaggaggaa gaggaggagg aggaggggct ggaggaagat gagccccgct
1921 tcaccatcat ccccaaccca ctggacagga gagaggaggc tggaggtgcc tccagcgagg
1981 aggaaagcgg tgaggacaca ggtccacagg atgctcagga gtatgggaac taccagccag
2041 ggtccctgtg tggctactgc tccttctgca atcgatgcac tgaatgtgag agctgtcact
2101 gtgatgagga gaacatgggt gagcactgcg accagtgcca gcactgtcag ttctgctatc
2161 tctgcccgct ggtctgcgaa acggtctgcg ctccaggaag ctacgttgac tatttctcct
2221 cgtcccttta tcaggccctg gcagacatgc tggaaacgcc ggaaccctga cccagtcgct
2281 cgactgcgac gcaggtgtac ctccccctgc cttccaaccc ctttccacga gctatattta
2341 tttctccgaa taaacgtgct ccccg
//