LOCUS HUMCA6 1316 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human carbonic anhydrase isozyme VI (CA6) mRNA, complete cds.
ACCESSION M57892 J05305
VERSION M57892.1
KEYWORDS carbonate dehydratase; carbonic anhydrase isozyme VI; secreted
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1316)
AUTHORS Aldred,P., Fu,P., Barrett,G., Penschow,J.D., Wright,R.D.,
Coghlan,J.P. and Fernley,R.T.
TITLE Human secreted carbonic anhydrase: cDNA cloning, nucleotide
sequence, and hybridization histochemistry
JOURNAL Biochemistry 30 (2), 569-575 (1991)
PUBMED 1899030
COMMENT Original source text: Human salivary gland, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1316
/db_xref="H-InvDB:HIT000195844"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1p36"
/tissue_type="salivary gland"
gene 1..1316
/gene="CA6"
mRNA <1..1316
/gene="CA6"
/note="G00-125-350; putative"
CDS 7..933
/gene="CA6"
/EC_number="4.2.1.1"
/note="putative"
/codon_start=1
/product="carbonic anhydrase isozyme VI"
/protein_id="AAA51892.1"
/db_xref="GDB:G00-125-350"
/translation="MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGG
QRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQIGLPSTMRMTVADG
IVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKTYDIAQDAPDGLA
VLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGS
LTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLKHRVVES
NFPNQEYTLGSEFQFYLHKIEEILDYLRRALN"
sig_peptide 7..57
/gene="CA6"
/note="G00-125-350; putative"
mat_peptide 58..930
/gene="CA6"
/product="carbonic anhydrase isozyme VI"
/EC_number="4.2.1.1"
/note="G00-125-350; putative"
BASE COUNT 362 a 343 c 313 g 298 t
ORIGIN Chromosome 1.
1 aacaccatga gggccctggt gcttctgctg tccctgttcc tgctgggtgg ccaggcccag
61 catgtgtctg actggaccta ctcagaaggg gcactggacg aagcgcactg gccacagcac
121 taccccgcct gtgggggcca gagacagtcg cctatcaacc tacagaggac gaaggtgcgg
181 tacaacccct ccttgaaggg gctcaatatg acaggctatg agacccaggc aggggagttc
241 cccatggtca acaatggcca cacagtgcag atcggcctgc cctccaccat gcgcatgaca
301 gtggctgacg gcattgtata catagcccag cagatgcact ttcactgggg aggtgcgtcc
361 tcggagatca gcggctctga gcacaccgtg gacgggatca gacatgtgat cgagattcac
421 attgttcact acaattctaa atacaagacg tatgatatag cccaagatgc gccggatggt
481 ttggctgtac tggcagcctt cgttgaggtg aagaattacc ctgaaaacac ttattacagc
541 aacttcattt ctcatctggc caacatcaag tacccaggac aaagaacaac cctgactggc
601 cttgacgttc aggacatgct gcccaggaac ctccagcact actacaccta ccatggctca
661 ctcaccacgc ctccctgcac tgagaacgtc cactggtttg tgctggcaga ttttgtcaag
721 ctctccagga cacaggtttg gaagctggag aattccttac tggatcaccg caacaagacc
781 atccacaacg attaccgcag gacccagccc ctgaaacaca gagtggtgga atccaacttc
841 ccgaatcagg aatacactct aggctctgaa ttccagtttt acctacataa gattgaggaa
901 attcttgact acttaagaag agcattgaac tgaggaaagc taagaggaag attcaataat
961 attaactagc ttgaagcctg acctagccag aagtgcctgt ccgctgcagc cgcaccctac
1021 cttgtctaag aaaccatgtg tgtctggaac acgctgctcc cctgggcagc tgttgggatt
1081 ctgattaaag aggggaaacg atcatcctgg acaggaagtg agatggcttc agttcatgag
1141 acgggatctg agttagacat caccagtgga aattgattgg aatagaaact taaaggaaat
1201 ggaaccctaa ctattctccc atcaaatcat atatgttgac ctgtctgaat tataaaccag
1261 cctgaccttt cctttagcat tagatgtaat aaaataactt tggaaatttg tcattt
//