LOCUS HUMMALENAD 1923 bp mRNA linear HUM 27-APR-1993
DEFINITION Human mitochondrial NAD(P)+ dependent malic enzyme mRNA, complete
cds.
ACCESSION M55905
VERSION M55905.1
KEYWORDS NAD(P)+ -dependent malic enzyme.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1923)
AUTHORS Loeber,G., Infante,A.A., Maurer-Fogy,I., Krystek,E. and
Dworkin,M.B.
TITLE Human NAD(+)-dependent mitochondrial malic enzyme. cDNA cloning,
primary structure, and expression in Escherichia coli
JOURNAL J. Biol. Chem. 266 (5), 3016-3021 (1991)
PUBMED 1993674
COMMENT Original source text: Human fibrosarcoma cell line HS 913T, cDNA to
mRNA.
FEATURES Location/Qualifiers
source 1..1923
/db_xref="H-InvDB:HIT000195813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HS913T"
/tissue_type="fibrosarcoma"
gene 1..1923
/gene="NAD(P)+ -dependent malic enzyme"
CDS 90..1844
/gene="NAD(P)+ -dependent malic enzyme"
/EC_number="1.1.1.39"
/codon_start=1
/product="mitochondrial NAD(P)+ -dependent malic enzyme"
/protein_id="AAA36197.1"
/translation="MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQE
RQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQD
DIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVV
TDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFY
MGLYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTF
NDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSE
QEAQKKIWMFDKYGLLVKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGV
AGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFG
PVKLTDGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELA
QGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPEDKAKYVKERTWRSEYDSLL
PDVYEWPESASSPPVITE"
polyA_site 1923
/gene="NAD(P)+ -dependent malic enzyme"
BASE COUNT 599 a 373 c 436 g 515 t
ORIGIN
1 gctgagcatc gccagggcgg gcggcagggc gcggcctctc cgccgggtgt acctcctgtc
61 gcggcgcgag acctctggtg aaagaaaaga tgttgtcccg gttaagagta gtttccacca
121 cttgtacttt ggcatgtcga catttgcaca taaaagaaaa aggcaagcca cttatgctga
181 acccaagaac aaacaaggga atggcattta ctttacaaga acgacaaatg cttggtcttc
241 aaggacttct acctcccaaa atagagacac aagatattca agccttacga tttcatagaa
301 acttgaagaa aatgactagc cctttggaaa aatatatcta cataatggga atacaagaaa
361 gaaatgagaa attgttttat agaatactgc aagatgacat tgagagttta atgccaattg
421 tatatacacc gacggttggt cttgcctgct cccagtatgg acacatcttt agaagaccta
481 agggattatt tatttcgatc tcagacagag gtcatgttag atcaattgtg gataactggc
541 cagaaaatca tgttaaggct gttgtagtga ctgatggaga gagaattctg ggtcttggag
601 atctgggtgt ctatggaatg ggaattccag taggaaaact ttgtttgtat acagcttgtg
661 caggaatacg gcctgataga tgcctgccag tgtgtattga tgtgggaact gataatatcg
721 cactcttaaa agacccattt tacatgggct tgtaccagaa acgagatcgc acacaacagt
781 atgatgacct gattgatgag tttatgaaag ctattactga cagatatggc cggaacacac
841 tcattcagtt cgaagacttt ggaaatcata atgcattcag gttcttgaga aagtaccgag
901 aaaaatattg tactttcaat gatgatattc aagggacagc tgcagtagct ctagcaggtc
961 ttcttgcagc acaaaaagtt attagtaaac caatctccga acacaaaatc ttattccttg
1021 gagcaggaga ggctgctctt ggaattgcaa atcttatagt tatgtctatg gtagaaaatg
1081 gcctgtcaga acaagaggca caaaagaaaa tctggatgtt tgacaagtat ggtttattag
1141 ttaagggacg gaaagcaaaa atagatagtt atcaggaacc atttactcac tcagccccag
1201 agagcatacc tgatactttt gaagatgcag tgaatatact gaagccttca actattattg
1261 gagttgcagg tgctggccgt cttttcactc ctgatgtaat cagagccatg gcctctatca
1321 atgaaaggcc tgtaatattt gcattaagta atcctacagc acaggcagag tgcacggctg
1381 aagaagcata tacacttaca gagggcaggt gtttgtttgc cagtggcagt ccatttgggc
1441 cagtgaaact tacagatggg cgagtcttta caccaggtca aggaaacaat gtttatattt
1501 ttccaggtgt ggctttagct gttattctct gtaacacccg gcatattagt gacagtgttt
1561 tcctagaagc tgcaaaggcc ctgacaagcc aattgacaga tgaagagcta gcccaaggga
1621 gactttaccc accgcttgct aatattcagg aagtttctat taacattgct attaaagtta
1681 cagaatacct atatgctaat aaaatggctt tccgataccc agaacctgaa gacaaggcca
1741 aatatgttaa agaaagaaca tggcggagtg aatatgattc cctgctgcca gatgtgtatg
1801 aatggccaga atctgcatca agccctcctg tgataacaga atagaagcac tcccctgata
1861 aatactttct gtgctccagg gaaccccttt tttcagacaa gaagagataa tgtcttcagt
1921 ttt
//