LOCUS HUMTPPII 4446 bp mRNA linear HUM 07-MAR-1995
DEFINITION Homo sapiens tripeptidyl peptidase II mRNA, 3' end.
ACCESSION M55169 J05299
VERSION M55169.1
KEYWORDS tripeptidyl peptidase II.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4446)
AUTHORS Tomkinson,B. and Jonsson,A.K.
TITLE Characterization of cDNA for human tripeptidyl peptidase II: the
N-terminal part of the enzyme is similar to subtilisin
JOURNAL Biochemistry 30 (1), 168-174 (1991)
PUBMED 1670990
COMMENT Original source text: Human B-lymphocyte cell line SPL, and
fibroblast cell line AG 1523, cDNA to mRNA, clones A2 and F5.
FEATURES Location/Qualifiers
source 1..4446
/db_xref="H-InvDB:HIT000195771"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="A2"
/clone="F5"
/cell_line="AG 1523"
/cell_line="SPL"
/cell_type="B lymphocyte"
/cell_type="fibroblast"
/tissue_lib="lambda gt10"
/tissue_lib="lambda gt11"
gene 1..4446
/gene="tripeptidyl petidase II"
CDS 1..3585
/gene="tripeptidyl petidase II"
/codon_start=1
/product="tripeptidyl peptidase II"
/protein_id="AAA63263.1"
/translation="VTTDGKPKIVDIIDTTGSGDVNTATEVEPKDGEIVGLSGRVLKI
PASWTNPSGKYHIGIKNGYDFYPKALKERIQKERKEKIWDPVHRVALAEACRKQEEFD
VANNGSSQANKLIKEELQSQVELLNSFEKKYSDPGPVYDCLVWHDGEVWRACIDSNED
GDLSKSTVLRNYKEAQEYGSFGTAEMLNYSVNIYDDGNLLSIVTSGGAHGTHVASIAA
GHFPEEPERNGVAPGAQILSIKIGDTRLSTMETGTGLIRAMIEVINHKCDLVNYSYGE
ATHWPNSGRICEVINEAVWKHNIIYVSSAGNNGPCLSTVGCPGGTTSSVIGVGAYVSP
DMMVAEYSLREKLPANQYTWSSRGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNG
TSMSSPNACGGIALILSGLKANNIDYTVHSVRRALENTAVKADNIEVFAQGHGIIQVD
KAYDYLVQNTSFANKLGFTVTVGNNRGIYLRDPVQVAAPSDHGVGIEPVFPENTENSE
KISLQLHLALTSNSSWVQCPSHLELMNQCRHINIRVDPRGLREGLHYTEVCGYDIASP
NAGPLFRVPITAVIAAKVNESSHYDLAFTDVHFKPGQIRRHFIEVPEGATWAEVTVCS
CSSEVSAKFVLHAVQLVKQRAYRSHEFYKFCSLPEKGTLTEAFPVLGGKAIEFCIARW
WASLSDVNIDYTISFHGIVCTAPQLNIHASEGINRFDVQSSLKYEDLAPCITLKNWVQ
TLRPVSAKTKPLGSRDVLPNNRQLYEMVLTYNFHQPKSGEVTPSCPLLCELLYESEFD
SQLWIIFDQNKRQMGSGDAYPHQYSLKLEKGDYTIRLQIRHEQISDLERLKDLPFIVS
HRLSNTLSLDIHENHSFALLGKKKSSNLTLPPKYNQPFFVTSLPDDKIPKGAGPGCYL
AGSLTLSKTELGKKADVIPVHYYLIPPPTKTKNGSKDKEKDSEKEKDLKEEFTEALRD
LKIQWMTKLDSSDIYNELKETYPNYLPLYVARLHQLDAEKERMKRLNEIVDAANAVIS
HIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLVDALCRKGCALADHLLHTQAQDG
AISTDAEGKEEEGESPLDSLAETFWETTKWTDLFDNKVLTFAYKHALVNKMYGRGLKF
ATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMYPPDYCVF"
BASE COUNT 1432 a 820 c 924 g 1270 t
ORIGIN
1 gttacaactg atggaaaacc aaaaatcgtt gatatcattg atacaacagg aagtggcgat
61 gtgaatactg ctacagaagt agagccaaag gatggtgaga ttgttggcct ttcaggaaga
121 gtgcttaaga ttcctgcaag ctggacaaat ccctcaggca aatatcatat tggcataaaa
181 aatggctatg acttctatcc taaggcactc aaggaaagga tacagaaaga acggaaggaa
241 aaaatctggg accctgttca cagagtggcc cttgcagaag cctgtagaaa acaggaagaa
301 tttgatgttg ccaacaacgg ctcttctcaa gcaaataaac taatcaagga ggaacttcaa
361 agtcaagtgg aattgctaaa ttcttttgag aagaaataca gcgatcctgg ccctgtatat
421 gactgcttgg tatggcatga tggcgaagtc tggagagcct gcattgattc taatgaagat
481 ggggacttga gtaaatctac cgtgttgaga aactacaaag aagcccaaga atatggctct
541 tttggcacag ctgagatgtt gaattactcc gttaatatat acgatgatgg aaacctgctc
601 tccattgtga ccagcggagg agctcatggg acacatgtag ctagtatagc tgctggacac
661 tttccagaag aacctgaacg gaatggggta gctcctggtg ctcaaattct ttccatcaag
721 attggtgata caagactaag cacaatggaa acaggcacag gcctcataag agctatgata
781 gaagttataa atcataagtg tgatcttgtc aactacagtt acggagaagc aactcactgg
841 ccaaattctg ggagaatttg tgaagtaatt aatgaagcag tatggaagca taatataatt
901 tatgtttcaa gtgctggaaa taatggtcca tgcctgtcta cagttggttg tccaggtgga
961 actacatcaa gtgtgatagg tgttggtgct tatgtttctc ctgatatgat ggttgctgag
1021 tattcactga gagagaaatt acctgcaaat caatatactt ggtcttctag aggacctagt
1081 gctgacgggg cccttggtgt gagtatcagt gcgccaggag gagccattgc ttctgttcct
1141 aactggacac tgagagggac gcagctgatg aatggaacat ctatgtcttc ccccaatgca
1201 tgtggaggca ttgccctgat cctttcaggt ctgaaagcta ataacattga ctacacagtt
1261 cattcagtca gaagagctct agaaaacact gcagtgaagg ctgacaatat agaagtattt
1321 gctcaaggac atggtattat tcaggttgat aaagcctatg actacctcgt tcagaataca
1381 tcatttgcta ataaattagg ttttactgtt actgttggaa ataaccgtgg catctacctc
1441 cgagatcctg ttcaggtggc tgcaccttca gatcatggcg ttggcattga acctgtattt
1501 ccggagaaca cagaaaactc tgaaaaaata tcccttcagc ttcatttagc tctgacttca
1561 aattcatctt gggttcagtg tcccagccat ttggaactca tgaatcaatg tagacacata
1621 aacatacgtg tggatcccag gggcttaaga gaaggattgc attatacaga ggtatgtggc
1681 tatgatatag catcccctaa cgcaggtccg ctcttcagag ttccgatcac tgcagttata
1741 gcagcaaaag taaatgaatc atcacattat gatctagcct ttacagatgt acactttaaa
1801 cctggtcaaa ttcgaaggca ttttattgag gttcctgagg gtgcaacatg ggctgaagtg
1861 acagtgtgtt cgtgttcttc tgaggtgtca gcaaagtttg ttctacatgc agtccagctt
1921 gtgaagcaaa gagcatatcg aagccatgaa ttctataagt tttgttctct tccagagaaa
1981 ggaacactga ctgaagcttt tcctgtccta ggtggaaaag caattgaatt ttgcattgct
2041 cgttggtggg caagtctcag tgatgtcaac attgattata ccatttcttt ccatgggata
2101 gtgtgtactg ctcctcagtt aaacattcat gcatcggaag gaatcaaccg ctttgatgtt
2161 cagtcctcct tgaaatacga agatctggct ccctgcataa ctttgaagaa ctgggtccaa
2221 acactgcgcc cagtgagtgc aaaaacaaaa cctttaggat caagagatgt tttgccaaat
2281 aaccgtcaac tttatgagat ggtcctgaca tataactttc atcaacccaa gagtggggaa
2341 gtaactccaa gctgcccact actttgtgaa ctattatatg aatctgaatt tgacagccaa
2401 ctgtggatta tttttgacca gaacaaaaga cagatgggtt caggcgatgc ctatccacat
2461 cagtattctt tgaaactgga gaaaggagat tatacaattc gactacagat tcgccatgag
2521 caaatcagtg atttggaacg ccttaaagac cttccattta ttgtttctca tagattgtct
2581 aataccttga gcttagatat tcatgaaaat catagttttg cacttctagg gaagaagaaa
2641 tcaagcaatt tgacattacc acccaaatat aaccagccat tctttgttac ttccttacct
2701 gatgataaaa tacctaaagg ggcaggacct ggatgctatc ttgcaggatc cttaacattg
2761 tcaaagactg aactaggaaa gaaagctgat gtaatccctg ttcattacta cttaatacct
2821 ccaccaacaa agactaagaa tggcagcaaa gataaggaaa aagattcaga aaaagagaaa
2881 gatttaaaag aagagtttac tgaagcatta cgagatctta aaattcagtg gatgacaaag
2941 ctggattcta gtgacattta taacgaattg aaagaaacat atcctaatta tcttcctctg
3001 tacgttgcac gacttcatca attggatgct gaaaaggaac gaatgaaaag acttaatgaa
3061 attgttgatg cggcaaatgc tgttatttct catatagatc aaacagccct agcagtttat
3121 attgcaatga agactgatcc caggcctgat gcagctacta taaaaaatga catggacaaa
3181 caaaaatcca ccctcgtaga tgccctttgt aggaaaggtt gtgccctggc agaccatctt
3241 cttcacaccc aggctcaaga cggagccatt tccactgatg cagaaggaaa ggaggaggaa
3301 ggagaaagtc ctttggattc tctggcagaa acattttggg aaactactaa atggactgat
3361 ctctttgaca ataaggtttt gacatttgca tataaacatg cattagtaaa taaaatgtat
3421 gggagaggcc ttaaatttgc aactaaactt gtggaagaaa aaccaacaaa agaaaactgg
3481 aaaaattgta ttcaactgat gaagttactt ggatggaccc attgtgcatc ttttactgaa
3541 aactggctcc ccatcatgta tcctcccgat tattgcgtat tctaaaatag gaaacaagac
3601 tttaaatttt aaaaaaggaa gttttatagt gaatgggtat aaaaacaaat ttgtggcatt
3661 tttagtctaa tgcatgtttt catccactat ccagtactga ttattaaaat gacatgtatt
3721 tatcagagaa ttcactgacg tgtggcttaa tacatgtaaa tctagacctc tgacatcatg
3781 gtgttttctt aatgcctcac attgctggca cggggatgtg ccctgcctgc cagcacctag
3841 gacttcgagt tgggttgcag cttatgacat gcatgatagg ttttggaagg taacttttaa
3901 ctgcaaacct ataaagtact attttttatt ttataaatga acagggtttt aacgtgctca
3961 actttaattt ttttcaattg tatgaaggcc ttaaaaaagc tacattaagc gtagctaaaa
4021 ttatttattg gactaaaaac taacagaact tcatttccag aatttttttt tttttttttt
4081 ttttggcaaa tgtttacatt caattaaggg gaaaaagtag aaccagcaca aatgagtggc
4141 agttgctgga gcataactgc ttcaataaat cttcatcttg gggtaattac aggcaagtca
4201 ttttcacatc ctcttgaggt tcagagcatc agaatgaact ctatgaatac atgtgtaagt
4261 gccagacagc tgaatcttta tcaggtattg taaagataca catatgatat gtttattaaa
4321 attgaaataa tgtaaaacac atgaataaat ttgcaaaacc aagatcacag tacaccatat
4381 gcactctggt accttaattt ttttttataa ataataaaag tgaatattga agcttcttaa
4441 aaaaaa
//