LOCUS HUMLIPBSA 3004 bp mRNA linear HUM 07-MAR-1995
DEFINITION Human bile salt-activated lipase (BAL) mRNA, complete cds.
ACCESSION M54994 J05301
VERSION M54994.1
KEYWORDS bile salt-activated lipase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3004)
AUTHORS Baba,T., Downs,D., Jackson,K.W., Tang,J. and Wang,C.S.
TITLE Structure of human milk bile salt activated lipase
JOURNAL Biochemistry 30 (2), 500-510 (1991)
PUBMED 1988041
COMMENT Original source text: Human lactating breast, cDNA to mRNA, clones
G10-2 and G10-3.
FEATURES Location/Qualifiers
source 1..3004
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="9q34.3"
/clone="G10-2"
/clone="G10-3"
/sex="female"
/tissue_type="lactating breast"
gene 1..3004
/gene="CEL"
CDS 679..2907
/gene="CEL"
/EC_number="3.1.1.3"
/codon_start=1
/product="bile salt-activated lipase"
/protein_id="AAA63211.1"
/db_xref="GDB:G00-127-527"
/translation="MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLG
DSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLY
LNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVT
FNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGA
SVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQ
CLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIA
GTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWA
QDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKW
VGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHW
EPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDS
EATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAP
PVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVP
PTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVI
RF"
sig_peptide 679..738
/gene="CEL"
/note="G00-127-527"
mat_peptide 739..2904
/gene="CEL"
/product="bile salt-activated lipase"
/EC_number="3.1.1.3"
/note="G00-127-527"
regulatory 2985..2990
/regulatory_class="polyA_signal_sequence"
/gene="CEL"
/note="G00-127-527"
polyA_site 3004
/gene="CEL"
/note="G00-127-527"
BASE COUNT 644 a 995 c 793 g 572 t
ORIGIN
1 ctcaattgga ggatcaaagt tgagaaaagt aatattcgac atttttcgat tcaacggagt
61 ggccaccaag acgatgtcat agaagtctga acgagtctca gttccaattt ggtagaccac
121 ttcatacatc tttgttggat ttcctgtgta cttggtcttt gttttctcct cgatgtacat
181 tactgagcca gatataagat tgcttttgga tgcctgcaga agccctgagc aaacaagttt
241 attgccacct tctactgccc aaaggccaga atcagaacag gacagtgaca ccgcccccac
301 aaaggcattg atgtccgtgc tttggccata attgaccctc ataacaggag caatcatttc
361 attgaggaac ttctcagaaa agccggcctt ttgcaaggtt tcaagaagtg ttcgattaag
421 cattccaagg aagtcatctc ctcctagagc atgaagtaat ttttcgacac tactgaaggc
481 atagtcatga gactggtagc ggtagatcct catgaacttg tctaacacgt cctctaccca
541 catgtgcata cggagggatt gaaatccata gcgccaaact aatttaatca cgttaattat
601 gaaccagttg ctctcctcaa ataccagagt ctctccatta tatatcccca gtaggccacc
661 cagaggctga tgctcaccat ggggcgcctg caactggttg tgttgggcct cacctgctgc
721 tgggcagtgg cgagtgccgc gaagctgggc gccgtgtaca cagaaggtgg gttcgtggaa
781 ggcgtcaata agaagctcgg cctcctgggt gactctgtgg acatcttcaa gggcatcccc
841 ttcgcagctc ccaccaaggc cctggaaaat cctcagccac atcctggctg gcaagggacc
901 ctgaaggcca agaacttcaa gaagagatgc ctgcaggcca ccatcaccca ggacagcacc
961 tacggggatg aagactgcct gtacctcaac atttgggtgc cccagggcag gaagcaagtc
1021 tcccgggacc tgcccgttat gatctggatc tatggaggcg ccttcctcat ggggtccggc
1081 catggggcca acttcctcaa caactacctg tatgacggcg aggagatcgc cacacgcgga
1141 aacgtcatcg tggtcacctt caactaccgt gtcggccccc ttgggttcct cagcactggg
1201 gacgccaatc tgccaggtaa ctatggtctt cgggatcagc acatggccat tgcttgggtg
1261 aagaggaata tcgcggcctt cgggggggac cccaacaaca tcacgctctt cggggagtct
1321 gctggaggtg ccagcgtctc tctgcagacc ctctccccct acaacaaggg cctcatccgg
1381 cgagccatca gccagagcgg cgtggccctg agtccctggg tcatccagaa aaacccactc
1441 ttctgggcca aaaaggtggc tgagaaggtg ggttgccctg tgggtgatgc cgccaggatg
1501 gcccagtgtc tgaaggttac tgatccccga gccctgacgc tggcctataa ggtgccgctg
1561 gcaggcctgg agtaccccat gctgcactat gtgggcttcg tccctgtcat tgatggagac
1621 ttcatccccg ctgacccgat caacctgtac gccaacgccg ccgacatcga ctatatagca
1681 ggcaccaaca acatggacgg ccacatcttc gccagcatcg acatgcctgc catcaacaag
1741 ggcaacaaga aagtcacgga ggaggacttc tacaagctgg tcagtgagtt cacaatcacc
1801 aaggggctca gaggcgccaa gacgaccttt gatgtctaca ccgagtcctg ggcccaggac
1861 ccatcccagg agaataagaa gaagactgtg gtggactttg agaccgatgt cctcttcctg
1921 gtgcccaccg agattgccct agcccagcac agagccaatg ccaagagtgc caagacctac
1981 gcctacctgt tttcccatcc ctctcggatg cccgtctacc ccaaatgggt gggggccgac
2041 catgcagatg acattcagta cgttttcggg aagcccttcg ccacccccac gggctaccgg
2101 ccccaagaca ggacagtctc taaggccatg atcgcctact ggaccaactt tgccaaaaca
2161 ggggacccca acatgggcga ctcggctgtg cccacacact gggaacccta cactacggaa
2221 aacagcggct acctggagat caccaagaag atgggcagca gctccatgaa gcggagcctg
2281 agaaccaact tcctgcgcta ctggaccctc acctatctgg cgctgcccac agtgaccgac
2341 caggaggcca cccctgtgcc ccccacaggg gactccgagg ccactcccgt gccccccacg
2401 ggtgactccg agaccgcccc cgtgccgccc acgggtgact ccggggcccc ccccgtgccg
2461 cccacgggtg actccggggc cccccccgtg ccgcccacgg gtgactccgg ggcccccccc
2521 gtgccgccca cgggtgactc cggggccccc cccgtgccgc ccacgggtga ctccggggcc
2581 ccccccgtgc cgcccacggg tgactccggg gccccccccg tgccgcccac gggtgactcc
2641 ggcgcccccc ccgtgccgcc cacgggtgac gccgggcccc cccccgtgcc gcccacgggt
2701 gactccggcg ccccccccgt gccgcccacg ggtgactccg gggccccccc cgtgaccccc
2761 acgggtgact ccgagaccgc ccccgtgccg cccacgggtg actccggggc cccccctgtg
2821 ccccccacgg gtgactctga ggctgcccct gtgcccccca cagatgactc caaggaagct
2881 cagatgcctg cagtcattag gttttagcgt cccatgagcc ttggtatcaa gaggccacaa
2941 gagtgggacc ccaggggctc ccctcccatc ttgagctctt cctgaataaa gcctcatacc
3001 cctg
//