LOCUS HUMA2MGL 2041 bp mRNA linear HUM 30-OCT-1994
DEFINITION Human alpha-2-macroglobulin mRNA, 3' end.
ACCESSION M36501
VERSION M36501.1
KEYWORDS alpha-2-macroglobulin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2041)
AUTHORS Bell,G.I., Rall,L.B., Sanchez-Pescador,R., Merryweather,J.P.,
Scott,J., Eddy,R.L. and Shows,T.B.
TITLE Human alpha 2-macroglobulin gene is located on chromosome 12
JOURNAL Somat. Cell Mol. Genet. 11 (3), 285-289 (1985)
PUBMED 2408344
COMMENT Original source text: Human liver, cDNA to mRNA, clone pha2ml.
FEATURES Location/Qualifiers
source 1..2041
/db_xref="H-InvDB:HIT000195676"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12p13.3-p12.3"
gene 1..2041
/gene="A2M"
CDS <1..1932
/gene="A2M"
/note="alpha-2-macroglobulin"
/codon_start=1
/protein_id="AAA51552.1"
/db_xref="GDB:G00-119-639"
/translation="PAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAE
ALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSL
KLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLN
ETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTF
AQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITI
ALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKDLLAYAFALAGNQDKRKE
VLKSLNEEAVKKDNSVHWERPQKPKAPVGDFYEPQAPSAEVEMTSYVLLAYLTAQPAP
TSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQ
SSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEF
PFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVK
MLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYET
DEFAIAEYNAPCSKDLGNA"
BASE COUNT 561 a 528 c 481 g 471 t
ORIGIN
1 cccgccttcc tagctgtccc agtggagaag gaacaagcgc ctcactgcat ctgtgcaaac
61 gggcggcaaa ctgtgtcctg ggcagtaacc ccaaagtcat taggaaatgt gaatttcact
121 gtgagcgcag aggcactaga gtctcaagag ctgtgtggga ctgaggtgcc ttcagttcct
181 gaacacggaa ggaaagacac agtcatcaag cctctgttgg ttgaacctga aggactagag
241 aaggaaacaa cattcaactc cctactttgt ccatcaggtg gtgaggtttc tgaagaatta
301 tccctgaaac tgccaccaaa tgtggtagaa gaatctgccc gagcttctgt ctcagttttg
361 ggagacatat taggctctgc catgcaaaac acacaaaatc ttctccagat gccctatggc
421 tgtggagagc agaatatggt cctctttgct cctaacatct atgtactgga ttatctaaat
481 gaaacacagc agcttactcc agagatcaag tccaaggcca ttggctatct caacactggt
541 taccagagac agttgaacta caaacactat gatggctcct acagcacctt tggggagcga
601 tatggcagga accagggcaa cacctggctc acagcctttg ttctgaagac ttttgcccaa
661 gctcgagcct acatcttcat cgatgaagca cacattaccc aagccctcat atggctctcc
721 cagaggcaga aggacaatgg ctgtttcagg agctctgggt cactgctcaa caatgccata
781 aagggaggag tagaagatga agtgaccctc tccgcctata tcaccatcgc ccttctggag
841 attcctctca cagtcactca ccctgttgtc cgcaatgccc tgttttgcct ggagtcagcc
901 tggaagacag cacaagaagg ggaccatggc agccatgtat ataccaaaga cctgctggcc
961 tatgcttttg ccctggcagg taaccaggac aagaggaagg aagtactcaa gtcacttaat
1021 gaggaagctg tgaagaaaga caactctgtc cattgggagc gccctcagaa acccaaggca
1081 ccagtggggg atttttacga accccaggct ccctctgctg aggtggagat gacatcctat
1141 gtgctcctcg cttatctcac ggcccagcca gccccaacct cggaggacct gacctctgca
1201 accaacatcg tgaagtggat cacgaagcag cagaatgccc agggcggttt ctcctccacc
1261 caggacacag tggtggctct ccatgctctg tccaaatatg gagcagccac atttaccagg
1321 actgggaagg ctgcacaggt gactatccag tcttcaggga cattttccag caaattccaa
1381 gtggacaaca acaaccgcct gttactgcag caggtctcat tgccagagct gcctggggaa
1441 tacagcatga aagtgacagg agaaggatgt gtctacctcc agacatcctt gaaatacaat
1501 attctcccag aaaaggaaga gttccccttt gctttaggag tgcagactct gcctcaaact
1561 tgtgatgaac ccaaagccca caccagcttc caaatctccc taagtgtcag ttacacaggg
1621 agccgctctg cctccaacat ggcgatcgtt gatgtgaaga tggtctctgg cttcattccc
1681 ctgaagccaa cagtgaaaat gcttgaaaga tctaaccatg tgagccggac agaagtcagc
1741 agcaaccatg tcttgattta ccttgataag gtgtcaaatc agacactgag cttgttcttc
1801 acggttctgc aagatgtccc agtaagagat ctgaaaccag ccatagtgaa agtctatgat
1861 tactacgaga cggatgagtt tgcaattgct gagtacaatg ctccttgcag caaagatctt
1921 ggaaatgctt gaagaccaca aggctgaaaa gtgctttgct ggagtcctgt tctcagagct
1981 ccacagaaga cacgtgtttt tgtatcttta aagacttgat gaataaacac tttttctggt
2041 c
//