LOCUS HUMPEC12L 2344 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human cell 12-lipoxygenase mRNA, complete cds.
ACCESSION M35418
VERSION M35418.1
KEYWORDS lipoxygenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2344)
AUTHORS Funk,C.D., Furci,L. and FitzGerald,G.A.
TITLE Molecular cloning, primary structure, and expression of the human
platelet/erythroleukemia cell 12-lipoxygenase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (15), 5638-5642 (1990)
PUBMED 2377602
COMMENT Original source text: Homo sapiens cDNA to mRNA.
Draft entry and computer-readable sequence for [1] kindly submitted
by C.D.Funk, 20-JUN-1990.
FEATURES Location/Qualifiers
source 1..2344
/db_xref="H-InvDB:HIT000195634"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/cell_type="platelet/erythroleukemia"
gene 1..2344
/gene="ALOX12"
mRNA <1..2344
/gene="ALOX12"
/note="G00-127-547"
CDS 42..2033
/gene="ALOX12"
/codon_start=1
/product="12-lipoxygenase"
/protein_id="AAA60056.1"
/db_xref="GDB:G00-127-547"
/translation="MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARG
EEEEFDHDVAEDLGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQG
EDILSLPEGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDL
PPNMRFHEEKRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKV
RQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEA
DFILLDGIPANVIRGEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPSPSSPTPTLFLPS
DPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFPIPH
IRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADR
GLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLC
QAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPP
TTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVL
NQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI"
regulatory 2324..2329
/regulatory_class="polyA_signal_sequence"
/gene="ALOX12"
/note="G00-127-547"
BASE COUNT 514 a 692 c 642 g 496 t
ORIGIN
1 ggaggacccg gctcccctcg cctaagctgc tggggggcgc catgggccgc taccgcatcc
61 gcgtggccac cggggcctgg ctcttctccg ggtcgtacaa ccgcgtgcag ctttggctgg
121 tcgggacgcg cggggaggcg gagctggagc tgcagctgcg gccggcgcgg ggcgaggagg
181 aggagtttga tcatgacgtt gcagaggact tggggctcct gcagttcgtg aggctgcgca
241 agcaccactg gctggtggac gacgcgtggt tctgcgaccg catcacggtg cagggccctg
301 gagcctgcgc ggaggtggcc ttcccgtgct accgctgggt gcagggcgag gacatcctga
361 gcctgcccga gggcaccgcc cgcctgccag gagacaatgc tttggacatg ttccagaagc
421 atcgagagaa ggaactgaaa gacagacagc agatctactg ctgggccacc tggaaggaag
481 ggttacccct gaccatcgct gcagaccgta aggatgatct acctccaaat atgagattcc
541 atgaggagaa gaggctggac tttgaatgga cactgaaggc aggggctctg gagatggccc
601 tcaaacgtgt ttacaccctc ctgagctcct ggaactgcct agaagacttt gatcagatct
661 tctggggcca gaagagtgcc ctggctgaga aggttcgcca gtgctggcag gatgatgagt
721 tgttcagcta ccagttcctc aatggtgcca accccatgct gttgagacgc tcgacctctc
781 tgccctccag gctagtgctg ccctcgggga tggaagagct tcaggctcaa ctggagaaag
841 aacttcagaa tggttccctg tttgaagctg acttcatcct tctggatgga attccagcca
901 acgtgatccg aggagagaag caatacctgg ctgcccccct cgttatgctg aagatggagc
961 ccaatgggaa gctgcagccc atggtcatcc agattcagcc tcccagcccc agctctccaa
1021 ccccaacact gttcctgccc tcagaccccc cacttgcctg gctcctggca aagtcctggg
1081 tccgaaattc agatttccaa ctgcacgaga tccagtatca cttgctgaac actcacctgg
1141 tggctgaggt catcgctgtc gccaccatgc ggtgcctccc aggactgcac cccatcttca
1201 agttcccgat cccccatatc cgctacacca tggaaatcaa cacccgggcc cggacccaac
1261 tcatctcaga tggaggaatt tttgataagg cagtgagcac aggtggaggg ggccatgtac
1321 agttgctccg tcgggcggca gctcagctga cctactgctc cctctgtcct cctgacgacc
1381 tggctgaccg gggcctgctg ggactcccag gtgctctcta tgcccatgat gctttacggc
1441 tctgggagat cattgccagg tatgtggagg ggatcgtcca cctcttctac caaagggatg
1501 acatagtgaa gggggaccct gagctgcagg cctggtgtcg ggagatcacg gaggtggggc
1561 tgtgccaggc ccaggaccga ggtttccctg tctccttcca gtcccagagt caactctgcc
1621 atttcctcac catgtgcgtc ttcacgtgca ctgcccagca tgccgccatc aaccagggcc
1681 agctggactg gtatgcctgg gtccctaatg ctccatgcac aatgcggatg cccccaccca
1741 ccaccaagga agatgtgacg atggccacag tgatggggtc actacctgat gtccggcagg
1801 cctgtcttca aatggccatc tcatggcatc tgagtcgccg ccagccagac atggtgcctc
1861 tggggcacca caaagaaaaa tatttctcag gccccaagcc caaagctgtg ctaaaccaat
1921 tccgaacaga tttggaaaag ctagaaaagg agattacagc ccggaatgag caacttgact
1981 ggccctatga atatctgaag cccagctgca tagagaacag tgtcaccatc tgagccctag
2041 agtgactcta cctgcaagat ttcacatcag ctttaggact gacatttcta tcttgaattt
2101 catgctttcc taaagtctct gctgctaagg ctctatttcc tcccccagtt aaacccctac
2161 attagtatcc cactagccca ggggagcagt aaactttctc tgcaaagact agatcctttt
2221 ttacgctttg cagaccgcat agtcactgtc tcaactactc agctctcctg ctgcagcatg
2281 aaggcagcca cagacaacat ggaaatgagt gtgactatgt tccaataaaa ctttatggac
2341 actg
//