LOCUS HUMROSSA 1843 bp mRNA linear HUM 03-AUG-1993
DEFINITION Human 52-kD ribonucleoprotein Ro/SSA mRNA, complete cds.
ACCESSION M34551
VERSION M34551.1
KEYWORDS ribonucleoprotein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1843)
AUTHORS Itoh,K., Itoh,Y. and Frank,M.B.
TITLE Protein heterogeneity in the human Ro/SSA ribonucleoproteins. The
52- and 60-kD Ro/SSA autoantigens are encoded by separate genes
JOURNAL J. Clin. Invest. 87 (1), 177-186 (1991)
PUBMED 1985094
COMMENT Original source text: Human thymocyte, cDNA to mRNA, clone FI18.1.
Draft entry and computer-readable [or printed] sequence for
[Unpublished (1990)]
kindly submitted by M.B.Frank, 18-MAY-1990.
Author address: M.B.Frank
Oklahoma Medical Res Foundation
Arthritis and Immunology program
825 WE 13th St, Oklahoma City, OK 73104.
FEATURES Location/Qualifiers
source 1..1843
/db_xref="H-InvDB:HIT000195600"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 39..1466
/note="52-kD Ro/SSA ribonucleoprotein"
/codon_start=1
/protein_id="AAA36581.1"
/translation="MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVG
KGGGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLF
CEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEI
AIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKL
AQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVP
GLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGA
QHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGT
YPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGF
NDGGKNTAPLTLCPLNIGSQGSTDY"
regulatory 1827..1832
/regulatory_class="polyA_signal_sequence"
BASE COUNT 474 a 458 c 488 g 423 t
ORIGIN 1 bp upstream of EcoRI site.
1 gaattcgggc acactgctgt ttaacggcac acttgacaat ggcttcagca gcacgcttga
61 caatgatgtg ggaggaggtc acatgcccta tctgcctgga ccccttcgtg gagcctgtga
121 gcatcgagtg tggccacagc ttctgccagg aatgcatctc tcaggttggg aaaggtgggg
181 gcagcgtctg tcctgtgtgc cggcagcgct ttctgctcaa gaatctccgg cccaatcgac
241 agctagccaa catggtgaac aaccttaaag aaatcagcca ggaggccaga gagggcacac
301 agggggaacg gtgtgcagtg catggagaga gacttcacct gttctgtgag aaagatggga
361 aggccctttg ctgggtatgt gcccagtctc ggaaacaccg tgaccacgcc atggtccctc
421 ttgaggaggc tgcacaggag taccaggaga agctccaggt ggcattaggg gaactgagaa
481 gaaagcagga gttggctgag aagttggaag tggaaattgc aataaagaga gcagactgga
541 agaaaacagt ggaaacacag aaatctagga ttcacgcaga gtttgtgcag caaaaaaact
601 tcctggttga agaagaacag aggcagctgc aggagctgga gaaggatgag agggagcagc
661 tgagaatcct gggggagaaa gaggccaagc tggcccagca gagccaggcc ctacaggagc
721 tcatctcaga gctagatcga aggtgccaca gctcagcact ggaactgctg caggaggtga
781 taattgtcct ggaaaggagt gagtcctgga acctgaagga cctggatatt acctctccag
841 aactcaggag tgtgtgccat gtgccagggc tgaagaagat gctgaggaca tgtgcagtcc
901 acatcactct ggatccagac acagccaatc cgtggctgat actttcagaa gatcggagac
961 aagtgaggct tggagacacc cagcagagca tacctggaaa tgaagagaga tttgatagtt
1021 atcctatggt cctgggtgcc cagcactttc actctggaaa acattactgg gaggtagatg
1081 tgacaggaaa ggaggcctgg gacctgggtg tctgcagaga ctctgtgcgc aggaaggggc
1141 actttttgct tagttccaag agtggcttct ggacaatttg gttgtggaac aaacaaaaat
1201 atgaggctgg cacctacccc cagactcccc tccaccttca ggtgcctcca tgccaagttg
1261 ggattttcct ggactatgag gctggcatgg tctccttcta caacatcact gaccatggct
1321 ccctcatcta ctccttctct gaatgtgcct ttacaggacc tctgcggccc ttcttcagtc
1381 ctggtttcaa tgatggagga aaaaacacag cccctctaac cctctgtcca ctgaatattg
1441 gatcacaagg atccactgac tattgatggc tttctctgga cactgccact ctccccattg
1501 gcaccgcttc tcagccacaa accctgcctc ttttccccat gaactctgaa ccacctttgt
1561 ctctgcagag gcatccggat cccagcaagc gagctttagc agggaagtca cttcaccatc
1621 aacattcctg ccccagatgg ctttgtgatt ccctccagtg aagcagcctc cttatatttg
1681 gcccaaactc atcttgatca accaaaaaca tgtttctgcc ttctttatgg gacttaagtt
1741 ttttttttct cctctccatc tctaggatgt cgtctttggt gagatctcta ttatatcttg
1801 tatggtttgc aaaagggctt cctaaaaata aaaacccgaa ttc
//