LOCUS HUMGPIIBA 3333 bp mRNA linear HUM 11-JUN-1993
DEFINITION Human platelet glycoprotein IIb (GPIIb) mRNA, complete cds.
ACCESSION M34480
VERSION M34480.1
KEYWORDS platelet glycoprotein IIb.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3333)
AUTHORS Frachet,P., Uzan,G., Thevenon,D., Denarier,E., Prandini,M.H. and
Marguerie,G.
TITLE GPIIb and GPIIIa amino acid sequences deduced from human
megakaryocyte cDNAs
JOURNAL Mol. Biol. Rep. 14 (1), 27-33 (1990)
PUBMED 2345548
COMMENT Original source text: Human megakaryocytes, cDNA to mRNA, clone
IIb[3,4].
FEATURES Location/Qualifiers
source 1..3333
/db_xref="H-InvDB:HIT000195597"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 1..3333
/product="GPIIb mRNA"
CDS 33..3152
/note="platelet glycoprotein IIb (GPIIb)"
/codon_start=1
/protein_id="AAA35926.1"
/translation="MARALCPLQALWLLEWVLLLLGACAAPPAWALNLDPVQLTFYAG
PNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFD
LRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGS
CFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPG
GYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFD
GDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRAEQMASYFGHSVAVTDVNGDGR
HDLLVGAPLYMDSRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIA
PLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGF
SLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQ
TKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLDL
DLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQ
EQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAV
HLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGN
LEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGE
REQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQ
CFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSA
PCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPP
LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRHT
LEEDDEEGE"
BASE COUNT 626 a 998 c 1040 g 669 t
ORIGIN
1 attcctgcct gggaggttgt ggaagaagga agatggccag agctttgtgt ccactgcaag
61 ccctctggct tctggagtgg gtgctgctgc tcttgggagc ttgtgctgcc cctccagcct
121 gggccttgaa cctggaccca gtgcagctca ccttctatgc aggccccaat ggcagccagt
181 ttggattttc actggacttc cacaaggaca gccatgggag agtggccatc gtggtgggcg
241 ccccgcggac cctgggcccc agccaggagg agacgggcgg cgtgttcctg tgcccctgga
301 gggccgaggg cggccagtgc ccctcgctgc tctttgacct ccgtgatgag acccgaaatg
361 taggctccca aactttacaa accttcaagg cccgccaagg actgggggcg tcggtcgtca
421 gctggagcga cgtcattgtg gcctgcgccc cctggcagca ctggaacgtc ctagaaaaga
481 ctgaggaggc tgagaagacg cccgtaggta gctgcttttt ggctcagcca gagagcggcc
541 gccgcgccga gtactccccc tgtcgcggga acaccctgag ccgcatttac gtggaaaatg
601 attttagctg ggacaagcgt tactgtgaag cgggcttcag ctcggtggtc actcaggccg
661 gagagctggt gcttggggct cctggcggct attatttctt aggtctcctg gcccaggctc
721 cagttgcgga tattttctcg agttaccgcc caggcatcct tttgtggcac gtgtcctccc
781 agagcctctc ctttgactcc agcaacccag agtacttcga cggctactgg gggtactcgg
841 tggccgtggg cgagttcgac ggggatctca acactacaga atatgtcgtc ggtgccccca
901 cttggagctg gaccctggga gcggtggaaa ttttggattc ctactaccag aggctgcatc
961 ggctgcgcgc agagcagatg gcgtcgtatt ttgggcattc agtcgctgtc actgacgtca
1021 acggggatgg gaggcatgat ctgctggtgg gcgctccact gtatatggac agccgggcag
1081 accgaaaact ggccgaagtg gggcgtgtgt atttgttcct gcagccgcga ggcccccacg
1141 cgctgggtgc ccccagcctc ctgctgactg gcacacagct ctatgggcga ttcggctctg
1201 ccatcgcacc cctgggcgac ctcgaccggg atggctacaa tgacattgca gtggctgccc
1261 cctacggggg tcccagtggc cggggccaag tgctggtgtt cctgggtcag agtgaggggc
1321 tgaggtcacg tccctcccag gtcctggaca gccccttccc cacaggctct gcctttggct
1381 tctcccttcg aggtgccgta gacatcgatg acaacggata cccagacctg atcgtgggag
1441 cttacggggc caaccaggtg gctgtgtaca gagctcagcc agtggtgaag gcctctgtcc
1501 agctactggt gcaagattca ctgaatcctg ctgtgaagag ctgtgtccta cctcagacca
1561 agacacccgt gagctgcttc aacatccaga tgtgtgttgg agccactggg cacaacattc
1621 ctcagaagct atccctaaat gccgagctgc agctggaccg gcagaagccc cgccagggcc
1681 ggcgggtgct gctgctgggc tctcaacagg caggcaccac cctggacctg gatctgggcg
1741 gaaagcacag ccccatctgc cacaccacca tggccttcct tcgagatgag gcagacttcc
1801 gggacaagct gagccccatt gtgctcagcc tcaatgtgtc cctaccgccc acggaggctg
1861 gaatggcccc tgctgtcgtg ctgcatggag acacccatgt gcaggagcag acacgaatcg
1921 tcctggactg tggggaagat gacgtatgtg tgccccagct tcagctcact gccagcgtga
1981 cgggctcccc gctcctagtt ggggcagata atgtcctgga gctgcagatg gacgcagcca
2041 acgagggcga gggggcctat gaagcagagc tggcggtgca cctgccccag ggcgcccact
2101 acatgcgggc cctaagcaat gtcgagggct ttgagagact catctgtaat cagaagaagg
2161 agaatgagac cagggtggtg ctgtgtgagc tgggcaaccc catgaagaag aacgcccaga
2221 taggaatcgc gatgttggtg agcgtgggga atctggaaga ggctggggag tctgtgtcct
2281 tccagctgca gatacggagc aagaacagcc agaatccaaa cagcaagatt gtgctgctgg
2341 acgtgccggt ccgggcagag gcccaagtgg agctgcgagg gaactccttt ccagcctccc
2401 tggtggtggc agcagaagaa ggtgagaggg agcagaacag cttggacagc tggggaccca
2461 aagtggagca cacctatgag ctccacaaca atggccctgg gactgtgaat ggtcttcacc
2521 tcagcatcca ccttccggga cagtcccagc cctccgacct gctctacatc ctggatatac
2581 agccccaggg gggccttcag tgcttcccac agcctcctgt caaccctctc aaggtggact
2641 gggggctgcc catccccagc ccctccccca ttcacccggc ccatcacaag cgggatcgca
2701 gacagatctt cctgccagag cccgagcagc cctcgaggct tcaggatcca gttctcgtaa
2761 gctgcgactc ggcgccctgt actgtggtgc agtgtgacct gcaggagatg gcgcgcgggc
2821 agcgggccat ggtcacggtg ctggccttcc tgtggctgcc cagcctctac cagaggcctc
2881 tggatcagtt tgtgctgcag tcgcacgcat ggttcaacgt gtcctccctc ccctatgcgg
2941 tgcccccgct cagcctgccc cgaggggaag ctcaggtgtg gacacagctg ctccgggcct
3001 tggaggagag ggccattcca atctggtggg tgctggtggg tgtgctgggt ggcctgctgc
3061 tgctcaccat cctggtcctg gccatgtgga aggtcggctt cttcaagcgg aaccggcaca
3121 ccctggaaga agatgatgaa gagggggagt gatggtgcag cctacactat tctagcagga
3181 gggttgggcg tgctacctgc accgcccctt ctccaacaag ttgcctccaa gctttgggtt
3241 ggagctgttc cattgggtcc tcttggtgtc gtttccctcc caacagagct gggctacccc
3301 ccctcctgct gcctaataaa gagactgagc cct
//