LOCUS HUMCAIX 2785 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human carbonic anhydrase I (CAI) mRNA, complete cds.
ACCESSION M33987
VERSION M33987.1
KEYWORDS carbonic anhydrase I.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2785)
AUTHORS Lowe,N., Brady,H.J., Barlow,J.H., Sowden,J.C., Edwards,M. and
Butterworth,P.H.
TITLE Structure and methylation patterns of the gene encoding human
carbonic anhydrase I
JOURNAL Gene 93 (2), 277-283 (1990)
PUBMED 2121614
COMMENT Original source text: Human EBV transformed SH B cell line DNA, and
cDNA to mRNA.
Since no intron sequences were provided this entry is treated as if
originating from an mRNA.
Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by N.Lowe, 09-MAY-1990.
Author address: N.Lowe
Department of Biochemistry
University College London
Gower Street, London
WC1E 6BT, U.K.
E-mail:UCBCMAR%EUCLID.UCL.AC.UK@CUNYVM.CUNY.EDU.
FEATURES Location/Qualifiers
source 1..2785
/db_xref="H-InvDB:HIT000195538"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="8q13-q22"
gene 1..2785
/gene="CA1"
regulatory 874..879
/regulatory_class="TATA_box"
/gene="CA1"
mRNA 902..2165
/gene="CA1"
/note="carbonic anhydrase I mRNA (alt.)"
mRNA 902..1939
/gene="CA1"
/note="carbonic anhydrase I mRNA (alt.)"
CDS 1048..1833
/gene="CA1"
/note="carbonic anhydrase I (EC 4.2.1.1)"
/codon_start=1
/protein_id="AAA51910.1"
/db_xref="GDB:G00-119-047"
/translation="MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTS
LKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTN
EHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQK
VLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESIS
VSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF"
BASE COUNT 840 a 603 c 492 g 850 t
ORIGIN
1 ctttagccca acagtcaaaa ataattgatg ctaccctaca aatgtccaaa actctagtat
61 atcatatttc taagttacag caaatattag tcctgctaaa ccagggagct ttggcaaaaa
121 tgttttttga cagtaaattt gtccttgatt atatattaac tagtcaaaga ggtgtttgta
181 acattattag agcttcttgt tgtaggtggg ttaacaccac caatcaagag gtcattctaa
241 cagaaagcct ggatcagaaa accatcaccc taaaaaaaca tgccttacat atttaacaca
301 ctctgaaatc cagtcaaaat atgactaaag gcccttgcca tgactgatgt attctcctgg
361 ccaacgccaa acaaatggga gcctggttac gagtcagcct tcagggactt gtcacatttc
421 tacttggttt cttccttgtt attgtcataa taaaatgttt tctatgctgt ttagtgcaac
481 ttaggcccta ttctgtagaa gtctcctcta ctattcaggc cactcaaaca ccccaaataa
541 ttgagttcaa aatcgacatc aagatataaa ggaatcagtg actaaatata tttcatatat
601 ggtattttta ttgattattg tgctgtcttg acctagtatg gaggccttgg ctagaggctg
661 gtcagtttcc tctcttgagc agctgattaa atccacaccc caaccacttc ccttatcagg
721 ttctcacact ctggggccac tatgtaccca ctctaatcac cacagggcca gacatcagac
781 aattaaggac agcgcccatg ccccaaagcc cgccaaaatt atgcaaatta ttcaaaatta
841 ttcaacctag ctaaccccac cctttttgct gtacataagc tgcccattcc ccctccagcc
901 tgtggtaccc agtcctcagg tgcaaccccc tgcgtggtcc tctgtggcag ccttctctca
961 ttcagagctg ttttccacag aggtagtgaa aagaactgga ttttcaagtt cactttgcaa
1021 gagaaaaaga aaactcagta gaagataatg gcaagtccag actggggata tgatgacaaa
1081 aatggtcctg aacaatggag caagctgtat cccattgcca atggaaataa ccaatcccct
1141 gttgatatta aaaccagtga aaccaaacat gacacctctc tgaaacctat tagtgtctcc
1201 tacaacccag ccacagccaa agaaattatc aatgtggggc attctttcca tgtaaatttt
1261 gaggacaacg ataaccgatc agtgctgaaa ggtggtcctt tctctgacag ctacaggctc
1321 tttcagtttc attttcactg gggcagtaca aatgagcatg gttcagaaca tacagtggat
1381 ggagtcaaat attctgccga gcttcacgta gctcactgga attctgcaaa gtactccagc
1441 cttgctgaag ctgcctcaaa ggctgatggt ttggcagtta ttggtgtttt gatgaaggtt
1501 ggtgaggcca acccaaagct gcagaaagta cttgatgccc tccaagcaat taaaaccaag
1561 ggcaaacgag ccccattcac aaattttgac ccctctactc tccttccttc atccctggat
1621 ttctggacct accctggctc tctgactcat cctcctcttt atgagagtgt aacttggatc
1681 atctgtaagg agagcatcag tgtcagctca gagcagctgg cacaattccg cagccttcta
1741 tcaaatgttg aaggtgataa cgctgtcccc atgcagcaca acaaccgccc aacccaacct
1801 ctgaagggca gaacagtgag agcttcattt tgatgattct gagaagaaac ttgtccttcc
1861 tcaagaacac agccctgctt ctgacataat ccagttaaaa taataatttt taagaaataa
1921 atttatttca atattagcaa gacagcatgc cttcaaatca atctgtaaaa ctaagaaact
1981 taaattttag ttcttactgc ttaattcaaa taataattag taagctagca aatagtaatc
2041 tgtaagcata agcttatctt aaattcaagt ttagtttgag gaattcttta aaattacaac
2101 taagtgattt gtatgtctat ttttttcagt ttatttgaac caataaaata attttatctc
2161 tttctttctg ttgtgcattc agtttctaaa accattaagt ttctactcca tttacattca
2221 aaaatcttaa atactttact tgcaagagta ttttgcttca aatacaacaa cctaagagca
2281 gctggagatg aaatattggg aaattcattt gcttactcct gaagacaaaa atatagctga
2341 gatgaccact ggatttaata tcgttatgct ggcccaacat tgctaccatt tgtgttgtct
2401 gtgatcaaaa tgattatctt ttatatagga agatgacgct tctggatatt gctttcactt
2461 cttctcccca cgttagcaag gacaatgctt ctctgccatt attacaacta gttagtttgc
2521 atggagaatc tttactttaa aattggaaga aaagtcacaa gtgaatggtt tataaaaatg
2581 ctaaagaagt cattcttgct tagaatcata tagaaacatc atgcaatctt ttagtcagat
2641 gtgcgcttca ccttatgcta tttttatctt taattgacac acaataattg tacatgttta
2701 tggagtatag tgtggtgttt tctgtttgtt tgtttgtttt ttgagacaag gtctcactct
2761 gccagtcagg gtggagtgcg atggt
//