LOCUS HUMCCDR 1157 bp mRNA linear HUM 27-APR-1993
DEFINITION Human chlordecone reductase mRNA, complete cds.
ACCESSION M33375
VERSION M33375.1
KEYWORDS chlordecone reductase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1157)
AUTHORS Winters,C.J., Molowa,D.T. and Guzelian,P.S.
TITLE Isolation and characterization of cloned cDNAs encoding human liver
chlordecone reductase
JOURNAL Biochemistry 29 (4), 1080-1087 (1990)
PUBMED 2187532
COMMENT Original source text: Human adult liver, cDNA to mRNA, clone
CCDR12.
FEATURES Location/Qualifiers
source 1..1157
/db_xref="H-InvDB:HIT000195511"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 44..970
/note="chlordecone reductase"
/codon_start=1
/protein_id="AAA35658.1"
/translation="MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEE
QVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLH
FPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEM
ILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP
VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSE
DMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY"
variation 103
/note="a in clone CCDR12; g in clone CCDR33"
variation 259
/note="c in clone CCDR12; g in clone CCDR33"
variation 432
/note="c in clone CCDR12; g in clone CCDR33"
variation 876
/note="t in clone CCDR12; a in clone CCDR33"
variation 929
/note="c in clone CCDR12; g in clone CCDR33"
BASE COUNT 330 a 266 c 270 g 291 t
ORIGIN
1 cgatcccaaa tatcagcgtg tagagctaaa tgatggtcac ttcatgcccg tattgggatt
61 tggcacctat gcacctccag aggttccgag gaacagagct gtagaggtca ccaaattagc
121 aatagaagct ggcttccgcc atattgattc tgcttattta tacaataatg aggagcaggt
181 tggactggcc atccgaagca agattgcaga tggcagtgtg aagagagaag acatattcta
241 cacttcaaag ctttggtgca ctttctttca accacagatg gtccaaccag ccttggaaag
301 ctcactgaaa aaacttcaac tggactatgt tgacctctat cttcttcatt tcccaatggc
361 tctcaagcca ggtgagacgc cactaccaaa agatgaaaat ggaaaagtaa tattcgacac
421 agtggatctc tctgccacat gggaggtcat ggagaagtgt aaggatgcag gattggccaa
481 gtccatcggg gtgtcaaact tcaactgcag gcagctggag atgatcctca acaagccagg
541 actcaagtac aagcctgtct gcaaccaggt agaatgtcat ccttacctca accagagcaa
601 actgctggat ttctgcaagt caaaagacat tgttctggtt gcccacagtg ctctgggaac
661 ccaacgacat aaactatggg tggacccaaa ctccccagtt cttttggagg acccagttct
721 ttgtgcctta gcaaagaaac acaaacgaac cccagccctg attgccctgc gctaccagct
781 gcagcgtggg gttgtggtcc tggccaagag ctacaatgag cagcggatca gagagaacat
841 ccaggttttt gaattccagt tgacatcaga ggatatgaaa gttctagatg gtctaaacag
901 aaattatcga tatgttgtca tggattttct tatggaccat cctgattatc cattttcaga
961 tgaatattag catagagggt gttgcacgac atctagcaga aggccctgtg tgtggatggt
1021 gatgcagagg atgtctctat gctggtgact ggacacacgg cctctggtta aatccctccc
1081 ctcctgcttg gcaacttcag ctagctagat atatccatgg tccagaaagc aaacataata
1141 aatttttatc ttgaagt
//