LOCUS HUMPP11A 2320 bp mRNA linear HUM 27-APR-1993
DEFINITION Human placental protein (PP11) mRNA, complete cds.
ACCESSION M32402
VERSION M32402.1
KEYWORDS placental protein; serine protease.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2320)
AUTHORS Grundmann,U., Roemisch,J., Siebold,B., Bohn,H. and Amann,E.
TITLE Cloning and expression of a cDNA encoding human placental protein
(PP11), a serine protease with diagnostic significance as a tumor
marker
JOURNAL Unpublished
COMMENT Original source text: Human placenta, cDNA to mRNA, (library
lambda-gt10).
Draft entry and printed sequence for [1] kindly submitted by
U.Grundmann, 02-MAR-90.
Author address: U.Grundmann
Department of Molecular Biololgy Research Institute
Behringwerke Ag, Postfach 1140, 3550
Marburg, Germany.
FEATURES Location/Qualifiers
source 1..2320
/db_xref="H-InvDB:HIT000195475"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 7..2320
/product="PP11 mRNA"
CDS 155..1264
/note="placental protein 11 (PP11) precursor"
/codon_start=1
/protein_id="AAA36464.1"
/translation="MRACISLVLAVLCGLAWAEDHKESEPLPQLEEETEEALASNLYS
APTSCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQS
ISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSKPTYAA
FINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEF
VDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYY
SHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQL
SLGGYPLAVRTYTWDKSTYGNGKKYIATAYIVSST"
sig_peptide 155..208
/note="placental protein 11 signal peptide"
mat_peptide 206..1261
/product="placental protein 11"
regulatory 2305..2310
/regulatory_class="polyA_signal_sequence"
misc_feature 2313..2317
/note="CATTG consensus site; putative"
BASE COUNT 636 a 547 c 581 g 556 t
ORIGIN
1 cttcctgaaa ggatctggag acaccagctc cacaagtcct ggtgtcttta aaaggatcag
61 cttgaggaat aaggctcgtc tgagagctgt gacattcatc tgactctagt gaaagtccaa
121 cagccactcc ctttttggcc tccaactggg caccatgagg gcctgcatct ccctggtatt
181 ggccgtgctg tgtggcctgg cctgggctga ggaccacaaa gagtcagagc cattgccaca
241 gctggaggaa gagacagaag aggccctcgc cagcaacttg tactcggcac ccacctcctg
301 ccagggccgc tgctacgaag cctttgacaa gcaccaccaa tgtcactgca atgcccgctg
361 ccaagagttt gggaactgct gcaaggattt tgagagcctg tgtagtgacc acgaggtctc
421 ccacagcagt gatgccataa caaaagagga gattcagagc atctctgaga agatctacag
481 ggcagacacc aacaaagccc agaaggaaga catcgttctc aatagccaaa actgcatctc
541 cccgtcagag accagaaacc aagtggatcg ctgcccaaag ccactcttca cttatgtcaa
601 tgagaagctg ttctccaagc ccacctatgc agccttcatc aacctcctca acaactacca
661 gcgggcaaca ggccatgggg agcacttcag tgcccaggag ctggccgagc aggacgcctt
721 cctcagagag atcatgaaga cagcagtcat gaaggagctc tacagcttcc tccatcacca
781 gaatcgctat ggctcagagc aagagtttgt cgatgacttg aagaacatgt ggtttgggct
841 ctattcgaga ggcaatgaag agggggactc gagtggcttt gaacatgtct tctcaggtga
901 ggtaaaaaaa ggcaaggtta ctggcttcca taactggatc cgcttctacc tggaggagaa
961 ggagggtctg gttgactatt acagtcacat ctacgatggg ccttgggatt cttaccccga
1021 tgtgctggca atgcagttca actgggacgg ctactataag gaagtgggct ctgctttcat
1081 cggcagcagc cctgagtttg agtttgcact ctactccctg tgcttcatcg ccaggccagg
1141 caaagtgtgc cagttaagcc tgggaggata tcccttagct gtccggacat atacctggga
1201 caagtccacc tatgggaatg gcaagaagta catcgccaca gcctacatag tgtcttccac
1261 ctaatagaac ttcgagccag aaaggggcat gagggctctt gcgagactga agtgctatct
1321 tctctggact agagagaaga gggagaggac tggaagggat caccaaatct caaagcaatg
1381 agaagcattc ctaaatccca aagtgcccac atgggaaaga gataaaatgt acaaattaga
1441 aaaatgtgga taaacagtca aacctttatc ctctagaatt ttggcaatgt tgactaagaa
1501 acagagtcca agcagagaag gtaggaaccc tccatagctc tctgccctga tgtgtggggg
1561 aactaggaag aagtcctttg acctcaccag gcctcatgct tccctttaat gtaaagggaa
1621 ggggtttgcc cactttcctc tttttggggt tggtgagagg gcaaaccctg atatttttac
1681 tgtgaaggtg ttttcagttg ttcttaggaa gaacagctga tagaaattca agattactat
1741 aatggctgtt attatacaca gctctgtaaa ctaccactca gccctgtgtt ggggtcctca
1801 aagaagtaag gccacagtaa tcaagcaagg gcctttggtt ttttccagag ttagatcctc
1861 tcagaacaga gtctgggaga actccaatgc tgaatggaga agggtaatag gttggttgca
1921 gtgaatgggc tgggggtggg gtggccttct ccaggcctga gtgtttttgt gtccagctca
1981 gtatctgcaa caagaagttt cccacttgtg gatgtttagt gcagccacag acttgtattt
2041 tgatccccaa ttttttttga aagagttctc ctcataggag gatgattcag catcagaaga
2101 agaaggaacc catagcttgg tgtcattaac ataattattt taagccttat ccagcagcca
2161 taatttgaat aactctacga gaccagagag actgtagttc cctattttaa cctcaattat
2221 gcatttgtcc ccaaccccac tgagaactaa atgctgtacc acagagccgg gtgtgaacta
2281 tggtttagaa ggttcaagtt tccaattaaa gtcattgaag
//