LOCUS HUMKSAA 1504 bp mRNA linear HUM 11-JUN-1993
DEFINITION Human adenocarcinoma-associated antigen (KSA) mRNA, complete cds.
ACCESSION M32325
VERSION M32325.1
KEYWORDS adenocarcinoma-associated antigen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1504)
AUTHORS Strnad,J., Hamilton,A.E., Beavers,L.S., Gamboa,G.C., Apelgren,L.D.,
Taber,L.D., Sportsman,J.R., Bumol,T.F., Sharp,J.D. and Gadski,R.A.
TITLE Molecular cloning and characterization of a human
adenocarcinoma/epithelial cell surface antigen complementary DNA
JOURNAL Cancer Res. 49 (2), 314-317 (1989)
PUBMED 2463074
COMMENT Original source text: Human cell line UCLA-P3, cDNA to mRNA, clone
AG[1,1338,933].
Draft entry and computer-readable sequence for [1] kindly submitted
by J.D. Sharp, 22-FEB-1990.
There are a few base differences between the sequence presented
here and that which appears in entry M26481. The difference occurs
mostly in the Poly-A signal.
FEATURES Location/Qualifiers
source 1..1504
/db_xref="H-InvDB:HIT000195473"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..1504
/product="adenocarcinoma-associated antigen mRNA"
CDS 155..1099
/note="adenocarcinoma-associated antigen precursor (KSA)"
/codon_start=1
/protein_id="AAA36151.1"
/translation="MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNR
QCQCTSVGAQNTVICSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDES
GLFKAKQCNGTSTCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSK
SLRTALQKEITTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEK
DVKGESLFHSKKMDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVV
MAVVAGIVVLVISRKKRMAKYEKAEIKEMGEMHRELNA"
sig_peptide 155..223
/note="adenocarcinoma-associated antigen signal peptide"
mat_peptide 398..1096
/product="adenocarcinoma-associated antigen"
regulatory 1486..1491
/regulatory_class="polyA_signal_sequence"
BASE COUNT 442 a 302 c 356 g 404 t
ORIGIN
1 gagcgagcac cttcgacgcg gtccggggac cccctcgtcg ctgtcctccc gacgcggacc
61 cgcgtgcccc aggcctcgcg ctgcccggcc ggctcctcgt gtcccactcc cggcgcacgc
121 cctcccgcgc ccctcttctc ggcgcgcgcg cagcatggcg cccccgcagg tcctcgcgtt
181 cgggcttctg cttgccgcgg cgacggcgac ttttgccgca gctcaggaag aatgtgtctg
241 tgaaaactac aagctggccg taaactgctt tgtgaataat aatcgtcaat gccagtgtac
301 ttcagttggt gcacaaaata ctgtcatttg ctcaaagctg gctgccaaat gtttggtgat
361 gaaggcagaa atgaatggct caaaacttgg gagaagagca aaacctgaag gggccctcca
421 gaacaatgat gggctttatg atcctgactg cgatgagagc gggctcttta aggccaagca
481 gtgcaacggc acctccacgt gctggtgtgt gaacactgct ggggtcagaa gaacagacaa
541 ggacactgaa ataacctgct ctgagcgagt gagaacctac tggatcatca ttgaactaaa
601 acacaaagca agagaaaaac cttatgatag taaaagtttg cggactgcac ttcagaagga
661 gatcacaacg cgttatcaac tggatccaaa atttatcacg agtattttgt atgagaataa
721 tgttatcact attgatctgg ttcaaaattc ttctcaaaaa actcagaatg atgtggacat
781 agctgatgtg gcttattatt ttgaaaaaga tgttaaaggt gaatccttgt ttcattctaa
841 gaaaatggac ctgacagtaa atggggaaca actggatctg gatcctggtc aaactttaat
901 ttattatgtt gatgaaaaag cacctgaatt ctcaatgcag ggtctaaaag ctggtgttat
961 tgctgttatt gtggttgtgg tgatggcagt tgttgctgga attgttgtgc tggttatttc
1021 cagaaagaag agaatggcaa agtatgagaa ggctgagata aaggagatgg gtgagatgca
1081 tagggaactc aatgcataac tatataattt gaagattata gaagaaggga aatagcaaat
1141 ggacacaaat tacaaatgtg tgtgcgtggg acgaagacat ctttgaaggt catgagtttg
1201 ttagtttaac atcatatatt tgtaatagtg aaacctgtac tcaaaatata agcagcttga
1261 aactggcttt accaatcttg aaatttgacc acaagtgtct tatatatgca gatctaatgt
1321 aaaatccaga acttggactc catcgttaaa attatttatg tgtaacattc aaatgtgtgc
1381 attaaatatg cttccacagt aaaatctgaa aaactgattt gtgattgaaa gctgcctttc
1441 tatttacttg agtcttgtac atacatactt ttttatgagc tatgaaataa aacattttaa
1501 actg
//