LOCUS HUM5AR 2102 bp mRNA linear HUM 27-APR-1993
DEFINITION Human steroid 5-alpha-reductase mRNA, complete cds.
ACCESSION M32313
VERSION M32313.1
KEYWORDS dihydrotestosterone; steroid 5-alpha-reductase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2102)
AUTHORS Andersson,S. and Russell,D.W.
TITLE Structural and biochemical properties of cloned and expressed human
and rat steroid 5 alpha-reductases
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (10), 3640-3644 (1990)
PUBMED 2339109
COMMENT Original source text: Human adult prostate, cDNA to mRNA.
Draft entry and computer-readable sequence [1] kindly submitted by
D.W. Russell, 23-FEB-1990, for release after publication.
FEATURES Location/Qualifiers
source 1..2102
/db_xref="H-InvDB:HIT000195466"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..2102
/product="steroid 5-alpha-reductase mRNA"
CDS 31..810
/note="steroid 5-alpha-reductase (EC 1.3.99.5)"
/codon_start=1
/protein_id="AAA35490.1"
/translation="MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALP
SHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIY
PFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLT
GMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQG
AAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF"
BASE COUNT 470 a 482 c 486 g 664 t
ORIGIN
1 gggcatggag cacgctgccc agccctggcg atggcaacgg cgacgggggt ggcggaggag
61 cgcctgctgg ccgcgctcgc ctacctgcag tgcgccgtgg gctgcgcggt cttcgcgcgg
121 aatcgtcaga cgaactcagt gtacggccgc cacgcgctgc ccagccacag gctccgagtg
181 ccggcgcggg ccgcctgggt ggtgcaggag ctgccctcgc tggccctgcc gctctaccag
241 tacgccagcg agtccgcccc gcgtctccgc agcgcgccca actgcatcct cctggccatg
301 ttcctcgtcc actacgggca tcggtgctta atttacccgt ttctgatgcg aggaggaaag
361 cctatgccac tgttggcatg tacaatggcg attatgttct gtacctgtaa cggctatttg
421 caaagcagat acttgagcca ttgtgcagtg tatgctgatg actgggtaac agatccccgt
481 tttctaatag gttttggctt gtggttaaca ggcatgttga taaacatcca ttcagatcat
541 atcctaagga atctcagaaa accaggagat actggataca aaataccaag gggaggctta
601 tttgaatacg taactgcagc caactatttt ggagaaatca tggagtggtg tggctatgcc
661 ctggccagct ggtctgtcca aggcgcggct tttgctttct tcacgttttg ttttttatct
721 ggtagagcaa aagagcatca tgagtggtac ctccggaaat ttgaagagta tccaaagttc
781 agaaaaatta taattccatt tttgttttaa gtgcgttttt catgaaatta tcttcaactt
841 gaagctttcc aatggcgctt ctctatggac tttgtaaata agttatatct ttgtaatttt
901 cctgctactt tatcattttc aagatgtcct ctaggaattt tttttctagt aattttgcaa
961 tctacctaat aagtacctaa atacgctgaa atggaggttg aatatcctac tgtgtaacag
1021 gtcagaattt caagctctgg gtaataactg ctgatatttt ttctaatttc aaatttacct
1081 cttttggcta tgtcttgcca agtgtgtatg agactagact ttacaactgt ctttgatggc
1141 attttcagaa caataaatgt cacaatccct tctatagccc cctacagtga tctcttcaag
1201 gtcaactgca gtgttgcttc cctcccccta tagggctgga atctgtctag gagccctctc
1261 tcggaggcca cagaggctgg gggtagccat tgtgcagtca tggcccgggg gaaacttgcc
1321 aaccttcgtg tcaggtgctg tgtgtaagtg gagaacttgg ggatagagga ggaagctcct
1381 cgtggccctt ccaaggtgag gcaaaggcat ctggacttgt tccagcccag cccaccgggt
1441 gacatcaccg ggcagggagg ggtgctggtg gtggttcata cggagtaagc tgctctgcct
1501 gtgtgagtgg ctcctgggcc ctaaacaggc acctttaggc catgggtcac tcaccgtgag
1561 ccatcaatgt gctctggtct gacatggttt ctctctgtct tctagtctag acctagtttt
1621 tttgttctgt tccccacgta tggatatagt agagattgtt gtctgtgaaa tttctctttt
1681 gtagattttg agttttccct tgtagtgtaa agaatgatca ctttctgtaa caataacaag
1741 accacttttt aagatttatc ctgtttgttc tttgttgatt gaaacataat aattgttaaa
1801 attctctaca gccttctttt tcttccatag ctaatcttcc ttctaatagt ttttgctttc
1861 tgttttgctg ttgttgcttt gcaaagcttt cccctcatag cctgtacctg ttatcaatat
1921 aaaataatct tcctgttgaa tgcttcatga cttgaattct actttgataa aaacattgcc
1981 atactgcttt ttatcttgat gaattcatct ggcattgctt tgccttatca tctcatctgg
2041 agtttttaaa tgccatttgt ttcagttgtc tttaacaaca taataaatag actttgccat
2101 tt
//