LOCUS HUMF12A 1990 bp mRNA linear HUM 19-JUL-1995
DEFINITION Human coagulation factor XII (Hageman) mRNA, 3' end.
ACCESSION M31315
VERSION M31315.1
KEYWORDS coagulation factor XII.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1990)
AUTHORS Tripodi,M., Citarella,F., Guida,S., Galeffi,P., Fantoni,A. and
Cortese,R.
TITLE cDNA sequence coding for human coagulation factor XII (Hageman)
JOURNAL Nucleic Acids Res. 14 (7), 3146 (1986)
PUBMED 3754331
COMMENT Original source text: Homo sapiens liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1990
/db_xref="H-InvDB:HIT000195419"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="5q33-qter"
/tissue_type="liver"
gene 1..1990
/gene="F12"
mRNA <1..1990
/gene="F12"
/product="CF XII mRNA"
CDS <1..1839
/gene="F12"
/note="coagulation factor XII precursor"
/codon_start=1
/protein_id="AAA70225.1"
/db_xref="GDB:G00-119-892"
/translation="LLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPC
HFPFQYHRQLYHKCTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQ
KGGTCVNMPSGPHCLCPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQC
KGPDAHCQRLASQACRTNPCLHGGRCLEVEGHRLCHCPVGYTGPFCDVDTKASCYDGR
GLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFV
LNRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQT
PGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHS
FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAF
SPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEG
AEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVC
EDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS"
sig_peptide <1..48
/gene="F12"
/note="coagulation factor XII signal peptide"
mat_peptide 49..1836
/gene="F12"
/product="coagulation factor XII"
BASE COUNT 358 a 685 c 610 g 337 t
ORIGIN
1 ctgctgctcc tggggttcct gctggtgagc ttggagtcaa cactttcgat tccaccttgg
61 gaagccccca aggagcataa gtacaaagct gaagagcaca cagtcgttct cactgtcacc
121 ggggagccct gccacttccc cttccagtac caccggcagc tgtaccacaa atgtacccac
181 aagggccggc caggccctca gccctggtgt gctaccaccc ccaactttga tcaggaccag
241 cgatggggat actgtttgga gcccaagaaa gtgaaagacc actgcagcaa acacagcccc
301 tgccagaaag gagggacctg tgtgaacatg ccaagcggcc cccactgtct ctgtccacaa
361 cacctcactg gaaaccactg ccagaaagag aagtgctttg agcctcagct tctccggttt
421 ttccacaaga atgagatatg gtatagaact gagcaagcag ctgtggccag atgccagtgc
481 aagggtcctg atgcccactg ccagcggctg gccagccagg cctgccgcac caacccgtgc
541 ctccatgggg gtcgctgcct agaggtggag ggccaccgcc tgtgccactg cccggtgggc
601 tacaccggac ccttctgcga cgtggacacc aaggcaagct gctatgatgg ccgcgggctc
661 agctaccgcg gcctggccag gaccacgctc tcgggtgcgc cctgtcagcc gtgggcctcg
721 gaggccacct accggaacgt gactgccgag caagcgcgga actggggact gggcggccac
781 gccttctgcc ggaacccgga caacgacatc cgcccgtggt gcttcgtgct gaaccgcgac
841 cggctgagct gggagtactg cgacctggca cagtgccaga ccccaaccca ggcggcgcct
901 ccgaccccgg tgtcccctag gcttcatgtc ccactcatgc ccgcgcagcc ggcaccgccg
961 aagcctcagc ccacgacccg gaccccgcct cagtcccaga ccccgggagc cttgccggcg
1021 aagcgggagc agccgccttc cctgaccagg aacggcccac tgagctgcgg gcagcggctc
1081 cgcaagagtc tgtcttcgat gacccgcgtc gttggcgggc tggtggcgct acgcggggcg
1141 cacccctaca tcgccgcgct gtactggggc cacagtttct gcgccggcag cctcatcgcc
1201 ccctgctggg tgctgacggc cgctcactgc ctgcaggacc ggcccgcacc cgaggatctg
1261 acggtggtgc tcggccagga acgccgtaac cacagctgtg agccgtgcca gacgttggcc
1321 gtgcgctcct accgcttgca cgaggccttc tcgcccgtca gctaccagca cgacctggct
1381 ctgttgcgcc ttcaggagga tgcggacggc agctgcgcgc tcctgtcgcc ttacgttcag
1441 ccggtgtgcc tgccaagcgg cgccgcgcga ccctccgaga ccacgctctg ccaggtggcc
1501 ggctggggcc accagttcga gggggcggag gaatatgcca gcttcctgca ggaggcgcag
1561 gtaccgttcc tctccctgga gcgctgctca gccccggacg tgcacggatc ctccatcctc
1621 cccggcatgc tctgcgcagg gttcctcgag ggcggcaccg atgcgtgcca gggtgattcc
1681 ggaggcccgc tggtgtgtga ggaccaagct gcagagcgcc ggctcaccct gcaaggcatc
1741 atcagctggg gatcgggctg tggtgaccgc aacaagccag gcgtctacac cgatgtggcc
1801 tactacctgg cctggatccg ggagcacacc gtttcctgat tgctcaggga ctcatctttc
1861 cctccttggt gattccgcag tgagagagtg gctggggcat ggaaggcaag attgtgtccc
1921 attcccccag tgcggccagc tccgcgccag gatggcgagg aactcaataa agtgctttga
1981 aaatgctgag
//