LOCUS HUMCNR 2548 bp mRNA linear HUM 23-SEP-1996
DEFINITION Human calcineurin B mRNA, complete cds.
ACCESSION M30773
VERSION M30773.1
KEYWORDS Ca2+/calmodulin-stimulated protein phosphatase; calcineurin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2548)
AUTHORS Guerini,D., Krinks,M.H., Sikela,J.M., Hahn,W.E. and Klee,C.B.
TITLE Isolation and sequence of a cDNA clone for human calcineurin B, the
Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein
phosphatase
JOURNAL DNA 8 (9), 675-682 (1989)
PUBMED 2558868
FEATURES Location/Qualifiers
source 1..2548
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="Hg2 and Hs1"
/tissue_type="brain stem and basal ganglia"
/clone_lib="library of R.Lazzarini"
gene 1..2548
/gene="CALNB"
CDS 759..1271
/gene="CALNB"
/codon_start=1
/product="calcineurin B"
/protein_id="AAB08721.1"
/db_xref="GDB:13940"
/translation="MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFM
SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMD
KDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGL
DIHKKMVVDV"
regulatory 2527..2532
/regulatory_class="polyA_signal_sequence"
/gene="CALNB"
BASE COUNT 696 a 561 c 553 g 738 t
ORIGIN
1 aggctggggg acaaccagag gccagggaga aagaggagac agaggaagca ccgagggtga
61 ctacgttgtc ttccctagat caattttctt ctggatggct cgtgctgagt ggtagatgag
121 cgaatcgatg agtccagcca ctgtgaacat gcccccaatg atggcgcaca cacctgtcag
181 gaagtgggtg aaggacctgt gcttctccgt cagcttcacc atcatgggcg agagctcata
241 gaggacgaag actccgggaa ggccttggtc gcccaacagc ccattggcaa ccttctcatg
301 tctggtcaca gagaactgat ttgtcctcag tacctctccg tccaccttca tgtacacagt
361 gggcaccacc ttcacaaagt gctgtaacac ctgtgaaggc agcggctccg gcgcgagcgc
421 gaggctgcag cccccgagtt tcccggccgt cttcgccccc tctccccctc ctttcttctt
481 ctctgcctct cctgcctctc gccgctgctc ctcccgcgct ctccggctct gaatgtcgac
541 cttaatttat ttccccctac cctgcccgct ccctcgcgtg cccaatcgcc cggccggcgc
601 gggccccgcg cgccgcctcc ccctccccac gcgcgccccc tccccgccgg cgacccgagg
661 gccgcagctg ggccgccgcc gccgtttcct gcgagccagc ctgagcgcaa cacttctccg
721 agccagcgag ccagcgagcc gccgacccgc cgagcaaaat gggaaatgag gcaagttatc
781 ctttggaaat gtgctcacac tttgatgcgg atgaaattaa aaggctagga aagagattta
841 agaagcttga tttggacaat tctggttctt tgagtgtgga agagttcatg tctctgcctg
901 agttacaaca gaatccttta gtacagcgag taatagatat attcgacaca gatgggaatg
961 gagaagtaga ctttaaagaa ttcattgagg gcgtctctca gttcagtgtc aaaggagata
1021 aggagcagaa attgaggttt gctttccgta tctatgacat ggataaagat ggctatattt
1081 ccaatgggga actcttccag gtattgaaga tgatggtggg gaacaatctg aaagatacac
1141 agttacagca aattgtagac aaaaccataa taaatgcaga taaggatgga gatggaagaa
1201 tatcctttga agaattctgt gctgttgtag gtggcctaga tatccacaaa aagatggtgg
1261 tagatgtgtg actcttatca gagagtacca cccaacactt ttgctttctt ctccatctct
1321 gaagatctgc tcaagacgtc cagcaatgct ctctgtgtat ttaaatggaa gtatttttct
1381 ctgtgaagcc acattttcca acatgagcct catgaagcca actaagtgtt attgaactgt
1441 aattctctca ataactcagt gtagcacttt aaagtctgaa ggacagcaac atgaaaagag
1501 catatcaatg tggtggagaa agggaagggg ttggcttttt aatttatttt tcttcatctt
1561 ttataacaag aaagtatcta tatatacata tgtaaatatt tatatataga tatatgtagc
1621 tttctatata tgtagtaggt tggctttaat ttaatatcct tgattcagaa acaaaacaat
1681 agagtacaaa agtgccaagc agaacataaa acatccttac ttttatttca cacagtttta
1741 tatatagata gaagactgta caatttgagc cgggtgttag gccagctatt ttccttttcc
1801 tgtgctttct cctttgagag attgacaaag catttgttaa cgtcctatta tttaccttaa
1861 ttacattttt gtaacaaagg agtctgtaac tttatttata cttatgaata tatccaggga
1921 ctacttctca ttgctgagca gcttttaata cacctctgct tgaggagaaa gtctagttca
1981 ttgctactgc caagagctag ttcttgtgtt catatagtaa ctgcacaggg cttatagctg
2041 cttcattctg ctactttgta actaggagcc attgcattta ttaaatgtcc ctcagtaacg
2101 ttaagtgcta gttgtgattt tatacataaa ggccagaagc tgtctgaggc aatcatgatt
2161 gattgtatgt atcacttact gaagaatacc tgaagtgatc atgtaactac ttataaggga
2221 tatccatttg tttgattaca tgggtaaata atttgtcatt aaacttgtgt ttgaatcatg
2281 aattcccttg tttcaaaaga cttgcagcta atctaaaaaa ctggtgatat ttaatatgca
2341 tgtatgtatc taaacaccca catatatttg tggtttaagt gtgagaaatc ttgctaatct
2401 atatgccaca gaagagcaaa attgtatcca aatttatgcc acttaaattt ctttaccacg
2461 agggatagag catgcatact ggtttttttt tcttgatttg cccatataat tggtaatgga
2521 taacttaata aatttgtgtg atataaaa
//