LOCUS HUMP42SA 2375 bp mRNA linear HUM 27-APR-1993
DEFINITION Human erythrocyte membrane protein 4.2 (P4.2S) mRNA, complete cds.
ACCESSION M30646
VERSION M30646.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2375)
AUTHORS Sung,L.A., Chien,S., Chang,L.S., Lambert,K., Bliss,S.A.,
Bouhassira,E.E., Nagel,R.L., Schwartz,R.S. and Rybicki,A.C.
TITLE Molecular cloning of human protein 4.2: a major component of the
erythrocyte membrane
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (3), 955-959 (1990)
PUBMED 1689063
COMMENT Original source text: Human sickle cell patient reticulocyte, cDNA
to mRNA, clones 7 and 16.
Draft entry and computer-readable sequence for [1] kindly submitted
by L.A.Sung, 12-DEC-1989, for release after publication.
FEATURES Location/Qualifiers
source 1..2375
/db_xref="H-InvDB:HIT000195382"
/organism="Homo sapiens"
/mol_type="mRNA"
/isolate="Sickle cell patient"
/db_xref="taxon:9606"
/cell_type="reticulocyte"
mRNA <1..2375
/product="protein 4.2 mRNA"
CDS 228..2303
/note="protein 4.2 (HUMP4.2S) (put.); putative"
/codon_start=1
/protein_id="AAA36402.1"
/translation="MGQALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILY
FRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSW
TISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLL
NQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGAL
LHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVAC
TVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWM
KRGLPCQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINAS
CVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLER
VEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQ
LAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTA
MATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVIS
ILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSV
TVVAPELSA"
BASE COUNT 583 a 638 c 669 g 485 t
ORIGIN
1 gaactggtcc aggagatacc agcagagagg gagtaggaga gaagaaacat gtcagggtgc
61 tcacaggagt agtgggggga ggttttgcta tttccagatt cttaagccaa caaaagtgcc
121 ttcatatttt ctgtctggaa gacagaaagc ccagaaggag cccagaagca acagtttgag
181 agaggcgctt tctgcggcca agtggataag aggagcggcc tgcaaccatg ggacaggccc
241 tgggtatcaa gagctgtgac tttcaggcag caagaaacaa tgaggagcac cacaccaagg
301 ccctcagctc ccggcgcctc tttgtgagga gggggcagcc cttcaccatc atcctgtact
361 tccgcgctcc agtccgtgca tttctgcctg ccctgaagaa ggtggccctc actgcacaaa
421 ctggagagca gccttccaag atcaacagga cccaagccac attcccaatt tccagtctgg
481 gggaccgaaa gtggtggagt gcagtggtgg aggagagaga tgcccagtcc tggaccatct
541 ctgtgaccac acctgcagac gctgtcattg gccactactc gcttctgctg caggtctcag
601 gcaggaagca actcctcttg ggtcagttca cactgctttt taacccctgg aatagagagg
661 atgctgtgtt cctgaagaat gaggctcagc gcatggagta cttgttgaac cagaatggtc
721 tcatctacct gggtacagct gactgcatcc aggcagagtc ctgggacttt ggccagttcg
781 agggggatgt cattgacctc agcctgcgct tgctgagcaa ggacaagcag gtagagaagt
841 ggagccagcc ggtgcacgtg gcccgtgtgt tgggtgcctt gctgcatttt ctcaaggagc
901 agagggtcct gcccaccccg cagacccagg ccacccagga aggggccttg ctgaacaagc
961 gccggggcag cgtgcccatc ctgcggcagt ggctcaccgg ccgaggccga cctgtgtatg
1021 atggccaggc ctgggtgttg gctgctgttg cttgcacagt gctgcgatgc ctgggaatcc
1081 ctgcccgcgt ggtgaccacg tttgcctcag cacagggcac cggtgggcgt cttctcatag
1141 atgaatacta taatgaggag ggacttcaga acggagaagg ccagagaggc agaatctgga
1201 tcttccagac ttccacagag tgctggatga agcgcggcct gccttgccag ggttatgatg
1261 gatggcagat tctgcaccca agtgctccta atggaggtgg agtcctgggg tcctgtgatc
1321 tggtgccggt cagagcagtc aaggagggga cgctggggct gaccccagca gtgtcagacc
1381 tttttgctgc cataaatgcc tcatgtgtgg tctggaagtg ctgtgaggat gggacactgg
1441 agttgactga ctccaacaca aagtatgttg gcaacaacat cagcaccaag ggtgtgggca
1501 gtgaccgctg cgaggacatc actcagaact acaagtatcc tgaagggtct cttcaggaaa
1561 aagaggtgct ggagagagtc gagaaagaga aaatggaacg tgagaaagac aacggcatcc
1621 gtcctcccag tctcgagact gccagtcctc tgtacctgct cttgaaagca cccagctccc
1681 tacccctgag aggggatgcc cagatctcag tgacgctggt taatcacagt gagcaggaga
1741 aggcagtgca gctggcaatt ggggtccagg ctgtacacta caacggtgtc cttgctgcca
1801 agctctggag gaagaagctg cacctcacgc tcagtgccaa cctggaaaag ataataacca
1861 tcggcctgtt cttctccaat tttgagcgaa acccacccga gaacaccttc cttagactca
1921 ccgccatggc aacacactct gaatccaacc ttagctgctt tgctcaggaa gacattgcca
1981 tttgtagacc acaccttgcc atcaagatgc cagagaaagc agagcagtat caacccctca
2041 cagcctcagt cagcctccag aactccctag atgcccccat ggaggactgt gtgatctcca
2101 tcctgggaag ggggctcatt cacagagaga ggagctacag attccgttca gtgtggcctg
2161 aaaacaccat gtgtgccaag ttccagttca cgccaacaca tgtggggctc cagagactca
2221 ctgtggaagt ggactgcaac atgttccaga acctaaccaa ctataaaagc gtcaccgtgg
2281 tagcccctga actatcagct taaacttcca gctctatcac cactctcctg ccaacccttg
2341 ttctacaatc taaaccaaac atgtgctagg aagag
//