LOCUS HUMGF1A 1360 bp mRNA linear HUM 27-APR-1993
DEFINITION Human erythroid DNA-binding protein (GF-1) mRNA, complete cds.
ACCESSION M30601
VERSION M30601.1
KEYWORDS DNA-binding protein; erythroid DNA binding protein; globin factor;
nuclear factor erythroid.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1360)
AUTHORS Zon,L.I., Tsai,S.F., Burgess,S., Matsudaira,P., Bruns,G.A. and
Orkin,S.H.
TITLE The major human erythroid DNA-binding protein (GF-1): primary
sequence and localization of the gene to the X chromosome
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (2), 668-672 (1990)
PUBMED 2300555
COMMENT Original source text: Human erythroid cell line K562, cDNA to mRNA,
clone K101.
Draft entry and computer-readable sequence for [1] kindly submitted
by S.H.Orkin, 08-DEC-1989.
FEATURES Location/Qualifiers
source 1..1360
/db_xref="H-InvDB:HIT000195374"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 59..1300
/note="erythroid DNA-binding protein"
/codon_start=1
/protein_id="AAA35885.1"
/translation="MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAA
ASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTG
LYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPN
SAYGGPDFSSTFFSPTGSPLNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRD
RTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGD
PVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGF
MVVAGGSGSGNCGEVASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTG
SFPTGPMPPTTSTTVVAPLSS"
BASE COUNT 269 a 456 c 379 g 256 t
ORIGIN Chromosome Xp11-21.
1 cccccaaggc gcccgaaccc tccgcaacca ccagcccagg ttaatcccca gaggctccat
61 ggagttccct ggcctggggt ccctggggac ctcagagccc ctcccccagt ttgtggatcc
121 tgctctggtg tcctccacac cagaatcagg ggttttcttc ccctctgggc ctgagggctt
181 ggatgcagca gcttcctcca ctgccccgag cacagccacc gctgcagctg cggcactggc
241 ctactacagg gacgctgagg cctacagaca ctccccagtc tttcaggtgt acccattgct
301 caactgtatg gaggggatcc cagggggctc accatatgcc ggctgggcct acggcaagac
361 ggggctctac cctgcctcaa ctgtgtgtcc cacccgcgag gactctcctc cccaggccgt
421 ggaagatctg gatggaaaag gcagcaccag cttcctggag actttgaaga cagagcggct
481 gagcccagac ctcctgaccc tgggacctgc actgccttca tcactccctg tccccaatag
541 tgcttatggg ggccctgact tttccagtac cttcttttct cccaccggga gccccctcaa
601 ttcagcagcc tattcctctc ccaagcttcg tggaactctc cccctgcctc cctgtgaggc
661 cagggagtgt gtgaactgcg gagcaacagc cactccactg tggcggaggg acaggacagg
721 ccactaccta tgcaacgcct gcggcctcta tcacaagatg aatgggcaga acaggcccct
781 catccggccc aagaagcgcc tgattgtcag taaacgagca ggtactcagt gcaccaactg
841 ccagacgacc accacgacac tgtggcggag aaatgccagt ggggatcccg tgtgcaatgc
901 ctgcggcctc tactacaagc tacaccaggt gaaccggcca ctgaccatgc ggaaggatgg
961 tattcagact cgaaaccgca aggcatctgg aaaagggaaa aagaaacggg gctccagtct
1021 gggaggcaca ggagcagccg aaggaccagc tggtggcttt atggtggtgg ctgggggcag
1081 cggtagcggg aattgtgggg aggtggcttc aggcctgaca ctgggccccc caggtactgc
1141 ccatctctac caaggcctgg gccctgtggt gctgtcaggg cctgttagcc acctcatgcc
1201 tttccctgga cccctactgg gctcacccac gggctccttc cccacaggcc ccatgccccc
1261 caccaccagc actactgtgg tggctccgct cagctcatga gggcacagag catggcctcc
1321 agaggagggg tggtgtcctt ctcctcttgt agccagaatt
//