LOCUS HUMNID 4898 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human nidogen mRNA, complete cds.
ACCESSION M30269
VERSION M30269.1
KEYWORDS nidogen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4898)
AUTHORS Nagayoshi,T., Sanborn,D., Hickok,N.J., Olsen,D.R., Fazio,M.J.,
Chu,M.-L., Knowlton,R., Mann,K., Deutzmann,R., Timpl,R. and
Uitto,J.
TITLE Human nidogen: complete amino acid sequence and structural domains
deduced from cDNAs, and evidence for polymorphism of the gene
JOURNAL DNA 8 (8), 581-594 (1989)
PUBMED 2574658
COMMENT Original source text: Human placenta and skin fibroblast, cDNA to
mRNA, clones cHFN-[5,7,8,12,16,26].
FEATURES Location/Qualifiers
source 1..4898
/db_xref="H-InvDB:HIT000195360"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1q43"
/cell_type="fibroblast"
/tissue_type="placenta; skin"
gene 1..4898
/gene="NID"
CDS 91..3834
/gene="NID"
/codon_start=1
/product="nidogen"
/protein_id="AAA59932.1"
/db_xref="GDB:G00-120-236"
/translation="MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDL
ELEDGDDFVSPALELSGALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGLFPPTFG
AVAPFLADLDTTDGLGKVYYREDLSPSITQRAAECVHRGFPEISFQPSSAVVVTWESV
APYQGPSRDPDQKGKRNTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKENNQVPAV
VAFSQGSVGFLWKSNGAYNIFANDRESIENLAKSSNSGQQGVWVFEIGSPATTNGVVP
ADVILGTEDGAEYDDEDEDYDLATTRLGLEDVGTTPFSYKALRRGGADTYSVPSVLSP
RRAATERPLGPPTERTRSFQLAVETFHQQHPQVIDVDEVEETGVVFSYNTDSRQTCAN
NRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKGRIFVGSSQVP
IVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAVEQDGFKNG
FSITGGEFTRQAEVTFVGHPGNLVIKQRFSGIDEHGHLTIDTELEGRVPQIPFGSSVH
IEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQECVHDDSR
PALPSTQQLSVDSVFVLYNQEEKILRYAFSNSIGPVREGSPDALQNPCYIGTHGCDTN
AACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCECVE
GYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQ
ACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHI
LGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTRPG
MTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTMRKTEAKAF
LHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLHGGEPTTIIRQDLGSPEGIAVDH
LGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDWNRDNP
KIETSYMDGTNRRILVQDDLGLPNGLHFDAFSSQLCWVDAGTNRAECLNPSQPSRRKA
LEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITTALSQ
CPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIERK"
sig_peptide 91..174
/gene="NID"
/note="G00-120-236"
mat_peptide 175..3831
/gene="NID"
/product="nidogen"
/note="G00-120-236"
BASE COUNT 1096 a 1417 c 1293 g 1092 t
ORIGIN
1 gaattccggc tgccaggggc gtccggttac atccccgcct tcctctgtcc tggccgcggg
61 accgggtttg cgggaccgca gttcgggaac atgttggcct cgagcagccg gatccgggct
121 gcgtggacgc gggcgctgct gctgccgctg ctgctggcgg ggcctgtggg ctgcctgagc
181 cgccaggagc tctttccctt cggccccgga cagggggacc tggagctgga ggacggggat
241 gacttcgtct ctcctgccct ggagctgagt ggggcgctcc gcttctacga cagatccgac
301 atcgacgcag tctacgtcac cacaaatggc atcattgcta cgagtgaacc cccggccaaa
361 gaatcccatc ccgggctctt cccaccaaca ttcggtgcag tcgccccttt cctggcggac
421 ttggacacga ccgatggcct ggggaaggtt tattatcgag aagacttatc cccctccatc
481 actcagcgag cagcagagtg tgtccacaga gggttcccgg agatctcttt ccagcctagt
541 agcgcggtgg ttgtcacttg ggaatccgtg gccccctacc aagggcccag cagggaccca
601 gaccagaaag gcaagagaaa cacgttccag gctgttctag cctcctctga ttccagctcc
661 tatgccattt tcctttatcc tgaggatggt ctgcagttcc atacgacatt ctcaaagaag
721 gaaaacaacc aagttcctgc cgtggttgca ttcagtcaag gttcagtggg attcttatgg
781 aagagcaacg gagcttataa catatttgct aatgacaggg aatcaattga aaatttggcc
841 aagagtagta actctgggca gcagggtgtc tgggtgtttg agattgggag tccagccacc
901 accaatggcg tggtgcctgc agacgtgatc ctcggaactg aagatggggc agagtatgat
961 gatgaggatg aagattatga cctggcgacc actcgtctgg gcctggagga tgtgggcacc
1021 acgcccttct cctacaaggc tctgagaagg ggaggtgctg acacatacag tgtgcccagc
1081 gtcctctccc cgcgccgggc agctaccgaa aggccccttg gacctcccac agagagaacc
1141 aggtctttcc agttggcagt ggagactttt caccagcagc accctcaggt catagatgtg
1201 gatgaagttg aggaaacagg agttgttttc agctataaca cggattcccg ccagacgtgt
1261 gctaacaaca gacaccagtg ctcggtgcac gcagagtgca gggactacgc cacgggcttc
1321 tgctgcagct gtgtcgctgg ctatacgggc aatggcaggc aatgtgttgc agaaggttcc
1381 ccccagcgag tcaatggcaa ggtgaaagga aggatctttg tggggagcag ccaggtcccc
1441 attgtctttg agaacactga cctccactct tacgtagtaa tgaaccacgg gcgctcctac
1501 acagccatca gcaccattcc cgagaccgtt ggatattctc tgcttccact ggccccagtt
1561 ggaggcatca ttggatggat gtttgcagtg gagcaggacg gattcaagaa tgggttcagc
1621 atcaccgggg gtgagttcac tcgccaggct gaggtgacct tcgtggggca cccgggcaat
1681 ctggtcatta agcagcggtt cagcggcatc gatgagcatg ggcacctgac catcgacacg
1741 gagctggagg gccgcgtgcc gcagattccg ttcggctcct ccgtgcacat tgagccctac
1801 acggagctgt accactactc cacctcagtg atcacttcct cctccacccg ggagtacacg
1861 gtgactgagc ccgagcgaga tggggcatct ccttcacgca tctacactta ccagtggcgc
1921 cagaccatca ccttccagga atgcgtccac gatgactccc ggccagccct gcccagcacc
1981 cagcagctct cggtggacag cgtgttcgtc ctgtacaacc aggaggagaa gatcttgcgc
2041 tacgctttca gcaactccat tgggcctgtg agggaaggct cccctgatgc tcttcagaat
2101 ccctgctaca tcggcactca tgggtgtgac accaacgcgg cctgtcgccc tggtcccagg
2161 acacagttca cctgcgagtg ctccatcggc ttccgaggag acgggcgaac ctgctatgat
2221 attgatgaat gttcagaaca accctcagtg tgtgggagcc acacaatctg caataatcac
2281 ccaggaacct tccgctgcga gtgtgtggag ggctaccagt tttcagatga gggaacgtgt
2341 gtggctgtcg tggaccagcg ccccatcaac tactgtgaaa ctggccttca taactgcgac
2401 ataccccagc gggcccagtg tatctacaca ggaggctcct cctacacctg ttcctgcttg
2461 ccaggctttt ctggggatgg ccaagcctgc caagatgtag atgaatgcca gccaagccga
2521 tgtcaccctg acgccttctg ctacaacact ccaggctctt tcacgtgcca gtgcaaacct
2581 ggttatcagg gagacggctt ccgttgcgtg cccggagagg tggagaaaac ccggtgccag
2641 cacgagcgag aacacattct cggggcagcg ggggcgacag acccacagcg acccattcct
2701 ccggggctgt tcgttcctga gtgcgatgcg cacgggcact acgcgcccac ccagtgccac
2761 ggcagcaccg gctactgctg gtgcgtggat cgcgacggcc gcgaggtgga gggcaccagg
2821 accaggcccg ggatgacgcc cccgtgtctg agtacagtgg ctcccccgat tcaccaagga
2881 cctgcggtgc ctaccgccgt gatccccttg cctcctggga cccatttact ctttgcccag
2941 actgggaaga ttgagcgcct gcccctggag ggaaatacca tgaggaagac agaagcaaag
3001 gcgttccttc atgtcccggc taaagtcatc attggactgg cctttgactg cgtggacaag
3061 atggtttact ggacggacat cactgagcct tccattggga gagctagtct acatggtgga
3121 gagccaacca ccatcattag acaagatctt ggaagtccag aaggtatcgc tgttgatcac
3181 cttggccgca acatcttctg gacagactct aacctggatc gaatagaagt ggcgaagctg
3241 gacggcacgc agcgccgggt gctctttgag actgacctgg tgaatcccag aggcattgta
3301 acggattccg tgagagggaa cctttactgg acagactgga acagagataa ccccaagatt
3361 gaaacttcct acatggacgg cacgaaccgg aggatccttg tgcaggatga cctgggcttg
3421 cccaatggac tgcacttcga tgcgttctca tctcagctct gctgggtgga tgcaggcacc
3481 aatcgggcgg aatgcctgaa ccccagtcag cccagcagac gcaaggctct cgaagggctc
3541 cagtatcctt ttgctgtgac gagctacggg aagaatctgt atttcacaga ctggaagatg
3601 aattccgtgg ttgctctcga tcttgcaatt tccaaggaga cggatgcttt ccaaccccac
3661 aagcagaccc ggctgtatgg catcaccacg gccctgtctc agtgtccgca aggccataac
3721 tactgctcag tgaacaatgg cggctgcacc cacctatgct tggccacccc agggagcagg
3781 acctgccgtt gccctgacaa caccttggga gttgactgta tcgaacggaa atgaagacaa
3841 gagtgcctta tttcctttcc aagtatttca cagcaacact ctacttgaag caacttggtc
3901 cagattgaaa agtgtcctct ggctgagtgg ccactaggcc cagacccagc ccagcctgag
3961 ccccaacaac aacttttccc tcactgttcc ccaaaacatg caccctggac ttctctaata
4021 gaaaagtctc cacccctaca caaggacaga accctccacc cctaccccca accctcagac
4081 agacttatac acccctgagt gaggattaca tgcccatccc agtgtcctag gaccttttcc
4141 caatactagc cccccagtgg tgaacagaac ctcccaaatt tgagttgcac ccttccctgt
4201 ggccttatga gctcagcctc gctttgaggt acccaccgtc ctgtcagctc cttgacctat
4261 gagctggggc ctgactagga aaagttggga gttaaggagg aaattagcat tccttaatgt
4321 tttgttttgg tgctctgaat ttcttcttta ttatagtcct atagttttac tcctcagttc
4381 ctcaccatca tcatcttgtc taagaccccc attataatat tcatgcgctg ctttttcatc
4441 aaaacctacc ctgtcctaga gatctatggg catttggtgg atgataatga gcagcccctc
4501 ccagatagaa tgtcaatatt tgagcagtag gatattggca tttgttagtt aaaggcttaa
4561 atcaaaagaa tgtccaatgg taggaatttc aaggtgtagg tcagatattt gagaataggg
4621 gatttttttg atgtgcctta aattatacca aagattacta attattcctc tttgcccaaa
4681 atacttgcat ccaaggttct agtctctgtt gctgtgctgg tctttagccc cactgctggc
4741 actgatgtcc ctcctttttc acggagacct atctgaggta caggatgggg ctggcaccag
4801 atgatgtccc accacagtcc ctcacctccg gcctccacat gacagaacca atttacactc
4861 aaccatgacc tcacccctcc ttggtttctc cctccccg
//