LOCUS HUMAE1 3637 bp mRNA linear HUM 27-APR-1993
DEFINITION Human anion exchange protein 1 (AE1, band 3) mRNA, complete cds.
ACCESSION M27819
VERSION M27819.1
KEYWORDS anion antiporter; anion exchange protein; integral membrane
protein; transmembrane protein; transport protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3637)
AUTHORS Lux,S.E., John,K.M., Kopito,R.R. and Lodish,H.F.
TITLE Cloning and characterization of band 3, the human erythrocyte
anion-exchange protein (AE1)
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (23), 9089-9093 (1989)
PUBMED 2594752
COMMENT Original source text: Human fetal liver, cDNA to mRNA, library of
B.Forget, clones pHB3-[45 A/B,9,22].
Draft entry and computer-readable sequence for [1] kindly submitted
by S.E.Lux, 12-SEP-1989.
FEATURES Location/Qualifiers
source 1..3637
/db_xref="H-InvDB:HIT000195191"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 115..2850
/note="anion exchange protein 1"
/codon_start=1
/protein_id="AAA35514.1"
/translation="MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATAT
DYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHL
TFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLK
HSHAGELEALGGVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILE
KIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHI
DYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLS
LVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPY
YLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGIL
FALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE
GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPKPQGP
LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFI
QDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLES
QITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTV
MGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVT
SLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS
LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMPV"
BASE COUNT 696 a 1101 c 1036 g 804 t
ORIGIN
1 cagcggctgc aggacttcac caagggaccc tgaggctcgt gagcagggac ccgcggtgcg
61 ggttatgctg ggggctcaga tcaccgtaga caactggaca ctcaggacca cgccatggag
121 gagctgcagg atgattatga agacatgatg gaggagaatc tggagcagga ggaatatgaa
181 gacccagaca tccccgagtc ccagatggag gagccggcag ctcacgacac cgaggcaaca
241 gccacagact accacaccac atcacacccg ggtacccaca aggtctatgt ggagctgcag
301 gagctggtga tggacgaaaa gaaccaggag ctgagatgga tggaggcggc gcgctgggtg
361 caactggagg agaacctggg ggagaatggg gcctggggcc gcccgcacct ctctcacctc
421 accttctgga gcctcctaga gctgcgtaga gtcttcacca agggtactgt tctcctagac
481 ctgcaagaga cctccctggc tggagtggcc aaccaactgc tagacaggtt tatctttgaa
541 gaccagatcc ggcctcagga ccgagaggag ctgctccggg ccctgctgct taaacacagc
601 cacgctggag agctggaggc cctggggggt gtgaagcctg cagtcctgac acgctctggg
661 gatccttcac agcctctgct cccccaacac tcctcactgg agacacagct cttctgtgag
721 cagggagatg ggggcacaga agggcactca ccatctggaa ttctggaaaa gattcccccg
781 gattcagagg ccacgttggt gctagtgggc cgcgccgact tcctggagca gccggtgctg
841 ggcttcgtga ggctgcagga ggcagcggag ctggaggcgg tggagctgcc ggtgcctata
901 cgcttcctct ttgtgttgct gggacctgag gccccccaca tcgattacac ccagcttggc
961 cgggctgctg ccaccctcat gtcagagagg gtgttccgca tagatgccta catggctcag
1021 agccgagggg agctgctgca ctccctagag ggcttcctgg actgcagcct agtgctgcct
1081 cccaccgatg ccccctccga gcaggcactg ctcagtctgg tgcctgtgca gagggagcta
1141 cttcgaaggc gctatcagtc cagccctgcc aagccagact ccagcttcta caagggccta
1201 gacttaaatg ggggcccaga tgaccctctg cagcagacag gccagctctt cgggggcctg
1261 gtgcgtgata tccggcgccg ctacccctat tacctgagtg acatcacaga tgcattcagc
1321 ccccaggtcc tggctgccgt catcttcatc tactttgctg cactgtcacc cgccatcacc
1381 ttcggcggcc tcctgggaga aaagacccgg aaccagatgg gagtgtcgga gctgctgatc
1441 tccactgcag tgcagggcat tctcttcgcc ctgctggggg ctcagcccct gcttgtggtc
1501 ggcttctcag gacccctgct ggtgtttgag gaagccttct tctcgttctg cgagaccaac
1561 ggtctagagt acatcgtggg ccgcgtgtgg atcggcttct ggctcatcct gctggtggtg
1621 ttggtggtgg ccttcgaggg tagcttcctg gtccgcttca tctcccgcta tacccaggag
1681 atcttctcct tcctcatttc cctcatcttc atctatgaga ctttctccaa gctgatcaag
1741 atcttccagg accacccact acagaagact tataactaca acgtgttgat ggtgcccaaa
1801 cctcagggcc ccctgcccaa cacagccctc ctctcccttg tgctcatggc cggtaccttc
1861 ttctttgcca tgatgctgcg caagttcaag aacagctcct atttccctgg caagctgcgt
1921 cgggtcatcg gggacttcgg ggtccccatc tccatcctga tcatggtcct ggtggatttc
1981 ttcattcagg atacctacac ccagaaactc tcggtgcctg atggcttcaa ggtgtccaac
2041 tcctcagccc ggggctgggt catccaccca ctgggcttgc gttccgagtt tcccatctgg
2101 atgatgtttg cctccgccct gcctgctctg ctggtcttca tcctcatatt cctggagtct
2161 cagatcacca cgctgattgt cagcaaacct gagcgcaaga tggtcaaggg ctccggcttc
2221 cacctggacc tgctgctggt agtaggcatg ggtggggtgg ccgccctctt tgggatgccc
2281 tggctcagtg ccaccaccgt gcgttccgtc acccatgcca acgccctcac tgtcatgggc
2341 aaagccagca ccccaggggc tgcagcccag atccaggagg tcaaagagca gcggatcagt
2401 ggactcctgg tcgctgtgct tgtgggcctg tccatcctca tggagcccat cctgtcccgc
2461 atccccctgg ctgtactgtt tggcatcttc ctctacatgg gggtcacgtc gctcagcggc
2521 atccagctct ttgaccgcat cttgcttctg ttcaagccac ccaagtatca cccagatgtg
2581 ccctacgtca agcgggtgaa gacctggcgc atgcacttat tcacgggcat ccagatcatc
2641 tgcctggcag tgctgtgggt ggtgaagtcc acgccggcct ccctggccct gcccttcgtc
2701 ctcatcctca ctgtgccgct gcggcgcgtc ctgctgccgc tcatcttcag gaacgtggag
2761 cttcagtgtc tggatgctga tgatgccaag gcaacctttg atgaggagga aggtcgggat
2821 gaatacgacg aagtggccat gcctgtgtga ggggcgggcc caggccctag accctccccc
2881 accattccac atccccacct tccaaggaaa agcagaagtt catgggcacc tcatggactc
2941 aggatcctcc tggagcagca gctgaggccc cagggctgtg ggtggggaag gaaggcgtgt
3001 ccaggagacc ttccacaaag ggtagcctgg cttttctggc tggggatggc cgatggggcc
3061 cacattaggg ggtttgttgc acagtccctc ctgttgccac actttcactg gggatcccgt
3121 gctggaagac ttagatctga gccctccctc ttcccagcac aggcaggggt agaagcaaag
3181 gcaggaggtg ggtgagcggg tggggtgctt gctgtgtgac cttgggtaag tcccttgacc
3241 tttccaggcc tatatttcct cttctgtaaa atgggtatat tgatgataat acccacatta
3301 caggatggtt actgaggacc aaagatacat gtaaaatagg gctttgtaaa ctccacaggg
3361 actgttctat agcagtcatc atttgtcttt gaacgtaccc aaggtcacat agctgggatt
3421 tgaactgagc cgtgcagctg ggatttgaac caggccttct gatttcaagg tccgagctct
3481 gtcctctgtc agtcatgcgt ccactttccc ttcccctgtg actcctccct tccccactct
3541 gctcccagcc cctaccttga gaccctcttc tctgggccca gagagaggcg tcctgggtga
3601 aggaaggtac aggcaggatg atccagggat tgggctg
//