LOCUS HUMATPSYB 10186 bp DNA linear HUM 22-AUG-2001
DEFINITION Homo sapiens ATP synthase beta subunit precursor (ATPSB) gene,
complete cds.
ACCESSION M27132
VERSION M27132.1
KEYWORDS ATP synthase beta subunit.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10186)
AUTHORS Neckelmann,N., Warner,C.K., Chung,A., Kudoh,J., Minoshima,S.,
Fukuyama,R., Maekawa,M., Shimizu,Y., Shimizu,N., Liu,J.D. and
Wallace,D.C.
TITLE The human ATP synthase beta subunit gene: sequence analysis,
chromosome assignment, and differential expression
JOURNAL Genomics 5 (4), 829-843 (1989)
PUBMED 2687158
REMARK Draft entry and computer-readable sequence for [1] kindly provided
by A.B.Chung, 11-AUG-1989.
FEATURES Location/Qualifiers
source 1..10186
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p13-qter"
/clone="g-beta-lambda 1"
/tissue_type="liver"
/dev_stage="fetus"
gene 2099..9908
/gene="ATPSB"
mRNA join(2099..2246,2728..2910,3126..3300,4123..4244,
4494..4678,5250..5408,5501..5623,7888..8100,8775..8976,
9663..9908)
/gene="ATPSB"
/product="ATP synthase beta subunit precursor"
exon 2099..2246
/gene="ATPSB"
/note="G00-119-718"
/number=1
CDS join(2120..2246,2728..2910,3126..3300,4123..4244,
4494..4678,5250..5408,5501..5623,7888..8100,8775..8976,
9663..9763)
/gene="ATPSB"
/EC_number="3.6.3.14"
/codon_start=1
/product="ATP synthase beta subunit precursor"
/protein_id="AAA51809.1"
/translation="MLGFVGRVAAAPASGALRRLTPSASLPPAQLLLRAAPTAVHPVR
DYAAQTSPSPKAGAATGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQH
LGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKT
KQFAPIHAEAPEFMEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIME
LINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPP
GARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPT
LATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAEL
GIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEED
KLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFY
MVGPIEEAVAKADKLAEEHSS"
sig_peptide join(2120..2246,2728..2747)
/gene="ATPSB"
mat_peptide join(2748..2910,3126..3300,4123..4244,4494..4678,
5250..5408,5501..5623,7888..8100,8775..8976,9663..9760)
/gene="ATPSB"
/product="ATP synthase beta subunit"
intron 2247..2727
/gene="ATPSB"
/number=A
exon 2728..2910
/gene="ATPSB"
/number=2
intron 2911..3125
/gene="ATPSB"
/number=B
exon 3126..3300
/gene="ATPSB"
/number=3
intron 3301..4122
/gene="ATPSB"
/number=C
exon 4123..4244
/gene="ATPSB"
/number=4
intron 4245..4493
/gene="ATPSB"
/number=D
exon 4494..4678
/gene="ATPSB"
/number=5
intron 4679..5249
/gene="ATPSB"
/number=E
exon 5250..5408
/gene="ATPSB"
/number=6
intron 5409..5500
/gene="ATPSB"
/number=F
exon 5501..5623
/gene="ATPSB"
/number=7
intron 5624..7887
/gene="ATPSB"
/number=G
exon 7888..8100
/gene="ATPSB"
/number=8
intron 8101..8774
/gene="ATPSB"
/number=H
exon 8775..8976
/gene="ATPSB"
/number=9
intron 8977..9662
/gene="ATPSB"
/number=I
exon 9663..9908
/gene="ATPSB"
/number=10
BASE COUNT 2468 a 2289 c 2375 g 3054 t
ORIGIN
1 cctcccaaag tgcagggatt acaggtgtaa gccaccacac ccagccaaaa tcctatgttt
61 tgatgcagtc cactgaaatt agttttgatc ccactccacc atggaatgat ttcctagttg
121 ccaaacccaa acccagagga tttttttcag ccctaatttt tttttcttct tttttatttt
181 tctttttttg ttgagacagg gtctcacaac gtcagccagc atggagtaca atggtgcaat
241 cttagctctc tgcaacctct acctcctggg ctcaagccat attcccatct cagcttcccc
301 agtagctggg actactggca catgccacac ctggctaatt gtgtgtctgt gtgtgtgtgt
361 gtgtgtgtgt ttattttttt acatattttt tagagacaag gtttcaccac gttgcccagg
421 ctggtattga actcctgggc tcaagttatc cacccacctc ggcttcccaa agtgttggga
481 ttactgggct ggccgtgccc agcccttttt acttatttta ttatttattt atttatttat
541 tttttattat tatttttgag acggagtctc gctctgtcac caggctggag tgcagtggca
601 cgatctcagc tcattgaaac ctccgccttc caggttcacg ccattctcct gcctcagcct
661 cctgagtagc tgggactaca ggcgcccgcc accacgccca gctaattttt gtatttttag
721 tagagacggg gtttcaccat gttggccagg atggtctaga tcgcttgacc tcatgatctg
781 cccacctcgg cctcccagag tgctgggatt acaggcgtga gccaccgtgc ccagcctatt
841 ttattttata tatttatttt atttttttag agagtctcac tctgtcgccc aagctggagt
901 gcagtggcgc atctcggctc actgcaagct ccgccatctc ggatttacgc cattctcctg
961 cctcagcctc ccaagtagct gggactacag gcgcccgcca ccacgcccgg ctaatttttt
1021 gtattgttag tagagaccgg gtttcactgt gttagtcagg atggtctcga tctcctgacc
1081 tcgtgatccg cccgccttgg cctcccatag tgctgggatt acaggcgtga gccaccgcgc
1141 ccagctaatt tttgtatttt tagtagagac ggggtttcac catgttagct aggctggtct
1201 cgaactcctg acctcaggtg atccacctgc ctcggcctcc gaaagtactg ggattacagg
1261 cgtgagccac cgctcccagc ctaccctaag aatttctatt cacatttcat agctgaggtc
1321 tctcagcttc cttcaaggtg gacaattctg tatctctagg tgacccaatt ttatcccctc
1381 ggtctttcgt gcacccagtt tatgctaacc aggaaccatc acattattgc attgtttgtt
1441 cacctggacc ttaaaaggaa ggttcttagt cttatttatc ttattattga gtctcctcaa
1501 tgccctgcta aagtactggt tacattagtt tatttcattt taataggttt aaatgataaa
1561 gatcctgtct aggttgctaa tctgtgcaat cgcctgggag cttgcaatct cactacttcg
1621 agagaaaaac cttattttgg ctctaaagag ggctcctgac ttcgccacgc tcaccttcag
1681 tggtgcttca ccgcactacc acttccctaa ccaccgcccc tatggctgtc acctagatca
1741 aggacctatc taaggagaaa gcccaaggac aggcaaagac aggccacgca ctttcaacag
1801 gaactcggcc cctttcctaa acgtagttcc tctgattacc ctgtccaacg gacgtcgcta
1861 tgatccaatt aagttttgag gctcagagtg acgccctcta acctcacact gtccaataaa
1921 aaaaggagtt tcagattagc accagttttg accaatggat gagaagatca gcgtgtatta
1981 acctgtagaa gcagcacaga gaatgatgag cagccagttc acccaatgga cctgcctact
2041 gcagcgtagg cctcgctcaa cggcaggaga gcaggcggct gcggttgctg cagccttcag
2101 tctccacccg gactacgcca tgttggggtt tgtgggtcgg gtggccgctg ctccggcctc
2161 cggggccttg cggagactca ccccttcagc gtcgctgccc ccagctcagc tcttactgcg
2221 ggccgctccg acggcggtcc atcctggtaa gtgcttttct ctaggagcta acgttccatt
2281 ttgccgcccc atgaccttga gccggggaac gatggtagct cgggcctaag ggatccgtgg
2341 tgttaaaagg atgcctggag ccgcgtcttg ctctctaatg gctggagaac aagaatggga
2401 cacccatagg aggtttcttc gacccagctc tgtcccattt tgtataaagt cctttgtgtg
2461 acggaaaagg tgcgggcagg tgcgttgacc ttccggttga ataggggtac tgaactctcg
2521 aaaaatgggg tcttgtgcat gcggatggga aggctgtgca ggcgctttat cgatcgctgc
2581 ggccttccct cttggacacg cgttccgtac aagcggaaag aggcctgact tcggctgagt
2641 tttcctctcc ttgtgtgtta agtcctggct tccgatgacc tttaactggc ctgaccccag
2701 ctccttccaa tatcttttgt ctgttagtca gggactatgc ggcgcaaaca tctccttcgc
2761 caaaagcagg cgccgccacc gggcgcatcg tggcggtcat tggcgcagtg gtggacgtcc
2821 agtttgatga gggactacca ccaattctaa atgccctgga agtgcaaggc agggagacca
2881 gactggtttt ggaggtggcc cagcatttgg gtaagtagag tttgttagga atagtaaaga
2941 ccttgtgtag cccaaatatc cccaaaacca agctgtctgc cttctatgat gattttatca
3001 aaatgacttt cgttcttctg agtttgctga agccacattt aggtactgag aaggagtctt
3061 ggtcgattta ggtcttgata ccaatttatc cttatgtata accctgcgat gcctgtatct
3121 aacaggtgag agcacagtaa ggactattgc tatggatggt acagaaggct tggttagagg
3181 ccagaaagta ctggattctg gtgcaccaat caaaattcct gttggtcctg agactttggg
3241 cagaatcatg aatgtcattg gagaacctat tgatgaaaga ggtcccatca aaaccaaaca
3301 gtaagttgct cttattgcat ctatgcacaa aggaacttct gttatttgca gttttacaca
3361 ttaaggtgac atgttctcct aaagcagaat ttttcttctg atacgttcga ttattaaaat
3421 cacacagtgc agtttcacct gaagaaatta ggatgcagaa tttctgattg acaaaagcct
3481 actacttgag gttttttttt ttgagaggga gtttcgctct cgactcactg caacctccac
3541 ctcctgggtt caagtgattc tcctgtctca gcctcctgag tagctgggat tacaggtgca
3601 tgccatcatg cccggctaat ttttgtattt ttagtacaga tggggtttca ccatgttggc
3661 caggctggtc tcgaactcct gattttgggt gattcccccc ccacctcggc cccccaaagt
3721 gctgggataa caggcatgag ccactgcgcc tggctagttg agtattttta agactcggtc
3781 ttatggctta ggtttaggag tctccaaaac ttgtaggttt ttgtatttgc tattgctatg
3841 tgagggaatg ctgttaggtt aaggctcagt aaaatgaaaa atttatgaca gttaaagtca
3901 gggaatggga ttattgtttc ctaagataat aattttcttt attgcagaaa gttgggttag
3961 atcctagatg atagtttatc tgatttatgt aagaaagggg aggtaagact gtggttcctc
4021 aggtaaaggg atggacttga gagttgatag ggagggatat ataagattat catttgcttt
4081 caacaaggtg aatagatact atcctctctt ctacctttac agatttgctc ccattcatgc
4141 tgaggctcca gagttcatgg aaatgagtgt tgagcaggaa attctggtga ctggtatcaa
4201 ggttgtcgat ctgctagctc cctatgccaa gggtggcaaa attggtatgt tattaagggg
4261 tacatatttt ccaaacctaa tatgggagga aaaactcata caatgttatg agtggatatt
4321 gacatctatt cctcactgat gagtacgttc tgactttcgt tcttctgagt ttgctgaagc
4381 cagatgcaat ttctgagaag gaataggatg gaaggaagca attacttttt ttgaagtttg
4441 cttatttagg aaagcagaac tcttaaatat tctttctttt caacctctta tagggctttt
4501 tggtggtgct ggagttggca agactgtact gatcatggag ttaatcaaca atgtcgccaa
4561 agcccatggt ggttactctg tgtttgctgg tgttggtgag aggacccgtg aaggcaatga
4621 tttataccat gaaatgattg aatctggtgt tatcaactta aaagatgcca cctctaaggt
4681 aagcattgag ctaattgatg tccacgtggt agttacgcca ggaaactatt gccaactgaa
4741 gccatgttct atattttcta tttaattttt ttttcttttt aagaaaatgt taatattttc
4801 attttcgtgt cccagggcct acaaaggaaa cctgttagtg ttttcccccc caacttccaa
4861 tacacaaatg gacattttct ttcctctttg atactgacat taaataacat ttccaggttt
4921 tctttttggt agatagtccc atcatttgaa agctaatttt gggagggctg gattggacgt
4981 ggtacatatg tttcagttaa gcctattttg tacttttcac ttaacttgaa taggttttta
5041 tttcctttct actatagttt tgccttacta atataagaag ctgtcttttt tttttgaact
5101 gcatctctaa tagggaaaag aaacttgcac acaaaaacgc tgacaccttc tgagaaagga
5161 tctgtggtcg tttctccgat ttgggaacct tcagtatgtg gcttctctac tcctttgtca
5221 ggttttacga ttatgtatga ttactgcagg tagcgctggt atatggtcaa atgaatgaac
5281 cacctggtgc tcgtgcccgg gtagctctga ctgggctgac tgtggctgaa tacttcagag
5341 accaagaagg tcaagatgta ctgctattta ttgataacat ctttcgcttc acccaggctg
5401 gttcagaggt aagagggaag gcttgagagg acctggttca tctggccttt cttcggatga
5461 ggctaaggat gtagacacct aagacctttt tttcttttag gtgtctgcat tattgggccg
5521 aatcccttct gctgtgggct atcagcctac cctggccact gacatgggta ctatgcagga
5581 aagaattacc actaccaaga agggatctat cacctctgta caggtaagaa aaattacata
5641 gatgaagatc tgatttgtat aaaggcaggg tgcagtggtg catctcagct actgaggagg
5701 ctgaggcagg aagattgctt gagcccaaga gatcagcctg gggaacaaag ctgtatgtat
5761 gtagagagat gtataaaact gactgggcca ggcgtggtgg ttcatgcctg taataccaac
5821 actttgggag gctgaggtac gcgatcatga ggtcaggagt taagacacca ccctggccaa
5881 cgtggtgaaa tcccgtctct actaaagata caaaaaatta gctgggcgtt gtggcaggcg
5941 cctgtaatcc caactactca gaggctgagg caggagaatc gcttgaatcc gggaggcaga
6001 ggttgcaatg agccaagatt ggggcactgc actccagcct gggtgacaga gtcagactct
6061 gcctcaaaaa attaaaaaaa aataaatgaa ggtatacatt taaatgtaga tcacaaagca
6121 atggtttcta gtctgagggg agtccggcgc tatatggaaa ctgagcatta aatatttact
6181 gtatcagggc tgagtgcagt ggctcacact tgtaattcca gcactttggg gccgggcacg
6241 tggctcacgc ctgtaatccc agcactttgg gaggccaagg caggcggatc atgaggtcag
6301 gagatcaaga ccatcctgac ttaacacagt gaaaccccat ctctactaaa aatacaaaaa
6361 attagctggg cgtggtggca cctgtctgta gttccagcta ctcgggaggc tgaggcagga
6421 gaattgcttg aacctgggag gcggaggttg caggaggttg tggtgagctg agattgggcc
6481 actcactcca gcctgggcgg cagagtgata atccgtctac aaaaaaaaaa aatttactgc
6541 attaatgtac tatacatttt caaatatata tagatgggat atatagtaaa attacataaa
6601 ttttacatat agtaaaaatg tggctaaact gtaggaactt ttcatgattc agtgtaatga
6661 actattgtgc aagaagtttt ttgttcttgt ttttaattct tttttttttt tttttgagac
6721 ggagtttcac tcttattgcc caggctggag tgcaatgggt gcgatctggg ctcactgcaa
6781 cctcctcctg ggttcaggtg attcctttgt ctcagcctcc tgagtagctg ggattatagg
6841 tgcccgacac caggcccggt taatttttgt atttttagta gagacggggt ttcaccatgt
6901 tagtcaggct ggtcttgaac tcctgacctc aggtgatctg cctgactcag cctcccaaag
6961 tgttgggatt ataggcttga gccactgtgc ccagcctctt ttttattttt ttattttttt
7021 taatttttat ttttttgaga cggagtctgt tgcctaggct acagtgtggt agcacagtct
7081 tggctcacta taacctccac ctcctgggtt caagcgattc acctgcttca gcctcctgca
7141 tagctgggat tacaggcatg catcaccatg cctggctaat ttttgtttcc gttttttttt
7201 ttttttttag tagagacccc cgtctctact ggtgtcgaac tcctgacctc gtgatctgcc
7261 ctccttggcc tcccaaagtg ctgggattat aggcatgagc caccgtgcct ggcccccagc
7321 ctcttgtttt taattctaaa agtgggcatt aaaatagtta aaataaaaga tgaagaacaa
7381 aaagaatgat actaaaaatt ccttccatca tggctgagag accagataat ctgtcagctt
7441 attcagcagg tattaggggt ggtaagaagg gtcttttgag tgctaagaat atggagtgag
7501 atgataaaga taggtcagaa ggggatggct taagtaaaat tactttggtt cgctggcgtg
7561 gtcgtcacgc ctataatccc cacacttttg ggaggccagg cgggtggatc acgaggtcag
7621 agttcaagac cagcctggcc aaagatagtg aaacccccgt ctctacaaaa aatacaaaaa
7681 caacattagc cgtgtgtggt gatgggcacc tgtagtccta gccactcggg aagctgagac
7741 agagaattgc ttgaatccag gaggcagagg ttgcagtgag ccgagattgc accactgcac
7801 tccagcctgg gcgacagagc gagaccctct caaaaaaaaa aaaaaaaatt tactttggtt
7861 cctgttcttc atgggatctc actttaggct atctatgtgc ctgctgatga cttgactgac
7921 cctgcccctg ctactacgtt tgcccatttg gatgctacca ctgtactgtc gcgtgccatt
7981 gctgagctgg gcatctatcc agctgtggat cctctagact ccacctctcg tatcatggat
8041 cccaacattg ttggcagtga gcattacgat gttgcccgtg gggtgcaaaa gatcctgcag
8101 gtgagtatat tactatgtgg gatcagtgtc cggaaagtca aaaagagggc ctgtggggac
8161 tatatgagga ctggatcttt cttagtgatt tgttttggag caaggaaagt tgaggctggc
8221 aattgctagt gagagctaat gaggtctctt gagtttccag ggtacttaac gctttggaat
8281 gcaatatttt tctttctttt tttttttttt tgagatgagt ctcactgtgt ctcccaagct
8341 ggagtgcagt ggtgccatct cggctcactg caacctccgc ctcccaggtt caagcgattc
8401 tcctgcctca gcctcctgag tacctgggat tacaggtgcg cgccaccatg cctggctact
8461 ttttgtattt ttagtagaga ccaggtttca tcagttggtc aggctggtct cgatctcctg
8521 acctcatgat ccacccaccg tggcctccca aagtggtggg attacagacg tgagccactg
8581 cgcccggcgg aatgcaatat ttttctaaca gcaccaaact aggactatgg agaacaagac
8641 actgatcttt cttggctgag ggccctcata acaccaccac cttctctgcc ccctagcatg
8701 taactttccc tttgttagct tgtcccaaat taaaggaatg agaatactta actcagtctt
8761 cttttttctc ataggactac aaatccctcc aggatatcat tgccatcctg ggtatggatg
8821 aactttctga ggaagacaag ttgaccgtgt cccgtgcacg gaaaatacag cgtttcttgt
8881 ctcagccatt ccaggttgct gaggtcttca caggtcatat ggggaagctg gtacccctga
8941 aggagaccat caaaggattc cagcagattt tggcaggtga gattttgagt acaaatcttg
9001 aatgtttact gtgctgtggt cccattccaa caaccgtcaa gcaatatatg taatatacta
9061 tgcttaatta tattttttaa tttaaaaaac aaacttaccc attgattttg tttgaaaata
9121 ctctacattt taattttgag tgtgattttg ttacttgatt ctctagctcc cttttatttt
9181 atatgtattt tttgagactg agtctctgtc gcccaggctg gagtacactg gtgcaatctt
9241 ggctcactgc aacctccacc tgccgggttc aagtgattct ccagcctcaa ccatccaaag
9301 tagctgggat tacaggcaca cgccaccacg cctggctaat ttttgtattt ttagtagcca
9361 tggggtttca ccatgttggc tgggcttgtc tcgaactcct gaccttaggt gatccgcctg
9421 ccttggcctc ccaaagtgct gggattacag gtgtaagcca ccgtgcctgg cccatgtgtt
9481 cttaattcat actgtatcat atcttgtaaa tttgatttgt gagggaaatt taagctttct
9541 aagatgacat gaattcatca cattctaact gatggcctga agtggtgagg aatgttacat
9601 gatgcagaaa gttgatatcc ctccgcttct tactcttttt ttttttctcc cccatcatac
9661 aggtgaatat gaccatctcc cagaacaggc cttctatatg gtgggaccca ttgaagaagc
9721 tgtggcaaaa gctgataagc tggctgaaga gcattcatcg tgaggggtct ttgtcctctg
9781 tactgtctct ctccttgccc ctaacccaaa aagcttcatt tttctgtgta ggctgcacaa
9841 gagccttgat tgaagatata ttctttctga acagtattta aggtttccaa taaaatgtac
9901 acccctcaga atttgtctga tctcttggtt ctgacaacat agtcaacact gaagggttat
9961 gtatttaatt ttagttttag agacacggtg tctggctgtg ttgccaagac tggtctctaa
10021 ctcctgggct cgagatctcc cacctcagtc tcctgagtag ctggggctac aggtgtatgt
10081 agtctcacat caccagcact gttttcaaca attagatttt tagagtggct ataagaagca
10141 gtttcagcat gaagtgggcc atgtatgttg aaattggtcc ttaaaa
//