LOCUS HUMIL2RBC 4034 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human interleukin 2 receptor beta chain (p70-75) mRNA, complete
cds.
ACCESSION M26062
VERSION M26062.1
KEYWORDS interleukin; interleukin 2 receptor beta-chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4034)
AUTHORS Hatakeyama,M., Tsudo,M., Minamoto,S., Kono,T., Doi,T., Miyata,T.,
Miyasaka,M. and Taniguchi,T.
TITLE Interleukin-2 receptor beta chain gene: generation of three
receptor forms by cloned human alpha and beta chain cDNA's
JOURNAL Science 244 (4904), 551-556 (1989)
PUBMED 2785715
COMMENT Original source text: Human lymphoid leukemia line (YT) cDNA to
mRNA.
Draft entry and computer readable copy of sequence [1] kindly
provided by M.Hatakeyama 12-JUL-1989.
FEATURES Location/Qualifiers
source 1..4034
/db_xref="H-InvDB:HIT000195031"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="22q13"
gene 1..4034
/gene="IL2RB"
CDS 132..1787
/gene="IL2RB"
/note="interleukin 2 receptor beta chain precursor
peptide"
/codon_start=1
/protein_id="AAA59143.1"
/db_xref="GDB:G00-118-822"
/translation="MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANI
SCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVD
IVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHY
FERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT
TWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKK
VLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVT
QLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDP
DEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGA
GEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREG
VSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV"
sig_peptide 132..209
/gene="IL2RB"
/note="interleukin 2 receptor beta chain signal peptide;
G00-118-822"
BASE COUNT 814 a 1315 c 1017 g 888 t
ORIGIN
1 gcagccagag ctcagcaggg ccctggagag atggccacgg tcccagcacc ggggaggact
61 ggagagcgcg cgctgccacc gccccatgtc tcagccaggg cttccttcct cggctccacc
121 ctgtggatgt aatggcggcc cctgctctgt cctggcgtct gcccctcctc atcctcctcc
181 tgcccctggc tacctcttgg gcatctgcag cggtgaatgg cacttcccag ttcacatgct
241 tctacaactc gagagccaac atctcctgtg tctggagcca agatggggct ctgcaggaca
301 cttcctgcca agtccatgcc tggccggaca gacggcggtg gaaccaaacc tgtgagctgc
361 tccccgtgag tcaagcatcc tgggcctgca acctgatcct cggagcccca gattctcaga
421 aactgaccac agttgacatc gtcaccctga gggtgctgtg ccgtgagggg gtgcgatgga
481 gggtgatggc catccaggac ttcaagccct ttgagaacct tcgcctgatg gcccccatct
541 ccctccaagt tgtccacgtg gagacccaca gatgcaacat aagctgggaa atctcccaag
601 cctcccacta ctttgaaaga cacctggagt tcgaggcccg gacgctgtcc ccaggccaca
661 cctgggagga ggcccccctg ctgactctca agcagaagca ggaatggatc tgcctggaga
721 cgctcacccc agacacccag tatgagtttc aggtgcgggt caagcctctg caaggcgagt
781 tcacgacctg gagcccctgg agccagcccc tggccttcag gacaaagcct gcagcccttg
841 ggaaggacac cattccgtgg ctcggccacc tcctcgtggg cctcagcggg gcttttggct
901 tcatcatctt agtgtacttg ctgatcaact gcaggaacac cgggccatgg ctgaagaagg
961 tcctgaagtg taacacccca gacccctcga agttcttttc ccagctgagc tcagagcatg
1021 gaggagacgt ccagaagtgg ctctcttcgc ccttcccctc atcgtccttc agccctggcg
1081 gcctggcacc tgagatctcg ccactagaag tgctggagag ggacaaggtg acgcagctgc
1141 tcctgcagca ggacaaggtg cctgagcccg catccttaag cagcaaccac tcgctgacca
1201 gctgcttcac caaccagggt tacttcttct tccacctccc ggatgccttg gagatagagg
1261 cctgccaggt gtactttact tacgacccct actcagagga agaccctgat gagggtgtgg
1321 ccggggcacc cacagggtct tccccccaac ccctgcagcc tctgtcaggg gaggacgacg
1381 cctactgcac cttcccctcc agggatgacc tgctgctctt ctcccccagt ctcctcggtg
1441 gccccagccc cccaagcact gcccctgggg gcagtggggc cggtgaagag aggatgcccc
1501 cttctttgca agaaagagtc cccagagact gggaccccca gcccctgggg cctcccaccc
1561 caggagtccc agacctggtg gattttcagc caccccctga gctggtgctg cgagaggctg
1621 gggaggaggt ccctgacgct ggccccaggg agggagtcag tttcccctgg tccaggcctc
1681 ctgggcaggg ggagttcagg gcccttaatg ctcgcctgcc cctgaacact gatgcctact
1741 tgtccctcca agaactccag ggtcaggacc caactcactt ggtgtagaca gatggccagg
1801 gtgggaggca ggcagctgcc tgctctgcgc cgagcctcag aaggaccctg ttgagggtcc
1861 tcagtccact gctgaggaca ctcagtgtcc agttgcagct ggacttctcc acccggatgg
1921 cccccaccca gtcctgcaca cttggtccat ccatttccaa acctccactg ctgctcccgg
1981 gtcctgctgc ccgagccagg aactgtgtgt gttgcagggg ggcagtaact ccccaactcc
2041 ctcgttaatc acaggatccc acgaatttag gctcagaagc atcgctcctc tccagccctg
2101 cagctattca ccaatatcag tcctcgcggc tctccagggc tccctgccct gacctcttcc
2161 ctgggttttc tgccccagcc tcctccttcc ctcccctccc cgtccacagg gcagcctgag
2221 cgtgctttcc aaaacccaaa tatggccacg ctccccctcg gttcaaaacc ttgcacaggt
2281 cccactgccc tcagccccac ttctcagcct ggtacttgta cctccggtgt cgtgtgggga
2341 catccccttc tgcaatcctc cctaccgtcc tcccgagcca ctcagagctc cctcacaccc
2401 cctctgttgc acatgctatt ccctggggct gctgtgcgct ccccctcatc taggtgacaa
2461 acttccctga ctcttcaagt gccggttttg cttctcctgg agggaagcac tgcctccctt
2521 aatctgccag aaacttctag cgtcagtgct ggagggagaa gctgtcaggg acccagggcg
2581 cctggagaaa gaggccctgt tactattcct ttgggatctc tgaggcctca gagtgcttgg
2641 ctgctgtatc tttaatgctg gggcccaagt aagggcacag atccccccac aaagtggatg
2701 cctgctgcat cttcccacag tggcttcaca gacccacaag agaagctgat ggggagtaaa
2761 ccctggagtc cgaggcccag gcagcagccc cgcctagtgg tgggccctga tgctgccagg
2821 cctgggacct cccactgccc cctccactgg aggggtctcc tctgcagctc agggactggc
2881 acactggcct ccagaagggc agctccacag ggcagggcct cattattttt cactgcccca
2941 gacacagtgc ccaacacccc gtcgtatacc ctggatgaac gaattaatta cctggcacca
3001 cctcgtctgg gctccctgcg cctgacattc acacagagag gcagagtccc gtgcccatta
3061 ggtctggcat gccccctcct gcaaggggct caacccccta ccccgacccc tccacgtatc
3121 tttcctaggc agatcacgtt gcaatggctc aaacaacatt ccaccccagc aggacagtga
3181 ccccagtccc agctaactct gacctgggag ccctcaggca cctgcactta caggccttgc
3241 tcacagctga ttgggcacct gaccacacgc ccccacaggc tctgaccagc agcctatgag
3301 ggggtttggc accaagctct gtccaatcag gtaggctggg cctgaactag ccaatcagat
3361 caactctgtc ttgggcgttt gaactcaggg agggaggccc ttgggagcag gtgcttgtgg
3421 acaaggctcc acaagcgttg agccttggaa aggtagacaa gcgttgagcc actaagcaga
3481 ggaccttggg ttcccaatac aaaaatacct actgctgaga gggctgctga ccatttggtc
3541 aggattcctg ttgcctttat atccaaaata aactcccctt tcttgaggtt gtctgagtct
3601 tgggtctatg ccttgaaaaa agctgaatta ttggacagtc tcacctcctg ccatagggtc
3661 ctgaatgttt cagaccacaa ggggctccac acctttgctg tgtgttctgg ggcaacctac
3721 taatcctctc tgcaagtcgg tctccttatc cccccaaatg gaaattgtat ttgccttctc
3781 cactttggga ggctcccact tcttgggagg gttacatttt ttaagtctta atcatttgtg
3841 acatatgtat ctatacatcc gtatctttta atgatccgtg tgtaccatct ttgtgattat
3901 ttccttaata ttttttcttt aagtcagttc attttcgttg aaatacattt ataaagaaaa
3961 atctttgtta ctctgtaaat gaaaaaaccc attttcgcta taaataaaag gtaactgtac
4021 aaaataagta caat
//