LOCUS HUMTHBS 1290 bp mRNA linear HUM 15-SEP-1994
DEFINITION Homo sapiens (clone lambda-TS-33) thrombospondin (THBS) mRNA, 5'
end.
ACCESSION M25631
VERSION M25631.1
KEYWORDS thrombospondin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1290)
AUTHORS Kobayashi,S., Eden-McCutchan,F., Framson,P. and Bornstein,P.
TITLE Partial amino acid sequence of human thrombospondin as determined
by analysis of cDNA clones: homology to malarial circumsporozoite
proteins
JOURNAL Biochemistry 25 (26), 8418-8425 (1986)
PUBMED 3030396
COMMENT On Sep 16, 1994 this sequence version replaced gi:341378.
Original source text: Homo sapiens umbilical vein endothelium cDNA
to mRNA.
FEATURES Location/Qualifiers
source 1..1290
/db_xref="H-InvDB:HIT000195002"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="lambda-TS-33"
/tissue_type="umbilical vein endothelium"
/clone_lib="lambda-gt11"
CDS 100..>1290
/note="Amino acid homology with malarial circumsporozoite
proteins bases 1255-1290"
/codon_start=1
/product="thrombospondin"
/protein_id="AAA36741.1"
/translation="MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGS
GRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRG
TLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFV
QEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFV
FGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDE
LSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVD
SCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCS
TSCGN"
sig_peptide 100..153
mat_peptide 154..>1290
/product="thrombospondin"
BASE COUNT 284 a 394 c 362 g 250 t
ORIGIN
1 gaattccgcg cccctccagc cctcgccgcc ctcgccaccg ctcccggccg ccgcgctccg
61 gtacacacag gatccctgct gggcaccaac agctccacca tggggctggc ctggggacta
121 ggcgtcctgt tcctgatgca tgtgtgtggc accaaccgca ttccagagtc tggcggagac
181 aacagcgtgt ttgacatctt tgaactcacc ggggccgccc gcaaggggtc tgggcgccga
241 ctggtgaagg gccccgaccc ttccagccca gctttccgca tcgaggatgc caacctgatc
301 ccccctgtgc ctgatgacaa gttccaagac ctggtggatg ctgtgcgggc agaaaagggt
361 ttcctccttc tggcatccct gaggcagatg aagaagaccc ggggcacgct gctggccctg
421 gagcggaaag accactctgg ccaggtcttc agcgtggtgt ccaatggcaa ggcgggcacc
481 ctggacctca gcctgaccgt ccaaggaaag cagcacgtgg tgtctgtgga agaagctctc
541 ctggcaaccg gccagtggaa gagcatcacc ctgtttgtgc aggaagacag ggcccagctg
601 tacatcgact gtgaaaagat ggagaatgct gagttggacg tccccatcca aagcgtcttc
661 accagagacc tggccagcat cgccagactc cgcatcgcaa aggggggcgt caatgacaat
721 ttccaggggg tgctgcagaa tgtgaggttt gtctttggaa ccacaccaga agacatcctc
781 aggaacaaag gctgctccag ctctaccagt gtcctcctca cccttgacaa caacgtggtg
841 aatggttcca gccctgccat ccgcactaac tacattggcc acaagacaaa ggacttgcaa
901 gccatctgcg gcatctcctg tgatgagctg tccagcatgg tcctggaact caggggcctg
961 cgcaccattg tgaccacgct gcaggacagc atccgcaaag tgactgaaga gaacaaagag
1021 ttggccaatg agctgaggcg gcctccccta tgctatcaca acggagttca gtacagaaat
1081 aacgaggaat ggactgttga tagctgcact gagtgtcact gtcagaactc agttaccatc
1141 tgcaaaaagg tgtcctgccc catcatgccc tgctccaatg ccacagttcc tgatggagaa
1201 tgctgtcctc gctgttggcc cagcgactct gcggacgatg gctggtctcc atggtccgag
1261 tggacctcct gttctacgag ctgtggcaat
//