LOCUS HUMELK1A 2266 bp mRNA linear HUM 07-NOV-1994
DEFINITION Homo sapiens tyrosine kinase (ELK1) oncogene mRNA, complete cds.
ACCESSION M25269
VERSION M25269.1
KEYWORDS ETS1 gene; oncogene; tyrosine kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2266)
AUTHORS Rao,V.N., Huebner,K., Isobe,M., ar-Rushdi,A., Croce,C.M. and
Reddy,E.S.
TITLE elk, tissue-specific ets-related genes on chromosomes X and 14 near
translocation breakpoints
JOURNAL Science 244 (4900), 66-70 (1989)
PUBMED 2539641
COMMENT On Sep 15, 1994 this sequence version replaced gi:341319.
Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2266
/db_xref="H-InvDB:HIT000194982"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Xp22.1-p11"
/clone="lambda-11"
/cell_line="COLO 320"
gene 1..2266
/gene="ELK1"
CDS 316..1602
/gene="ELK1"
/codon_start=1
/product="tyrosine kinase"
/protein_id="AAA52384.1"
/db_xref="GDB:G00-119-867"
/translation="MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVAR
LWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQ
PEVSVTSTMPNVAPAAIHAAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYS
TFTIQSLQPQPPPHPRPAVVLPNAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQ
VILTPPEAPNLKSEELNVEPGLGRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEV
PPQEGVPARLPAVVMDTAGQAGGHAASSPEISQPQKGRKPRDLELPLSPSLLGGPGPE
RTPGSGSGSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAK
LSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP"
BASE COUNT 457 a 731 c 605 g 473 t
ORIGIN
1 aattccgagc tgtagggaaa cgcaggggcg gcttctaggt gctgccgccg ccaccgccac
61 caccacctcc accgccgcct cggaacccag gcctgggggg cggtggggcc gcgtatggag
121 cccccgcccc ccggagctgc caacattgcc aacgccaccg ccacgctaca cacagcctca
181 actttcagga gacccgtccg tggccttatt tattccaccc ttcctgtaca tcgtagcgaa
241 tcaatccgtg gcgccgcact cctccgcatc cctctttaac agtacccctg ggatggcgtg
301 agcactcccc cagcgatgga cccatctgtg acgctgtggc agtttctgct gcagctgctg
361 agagagcaag gcaatggcca catcatctcc tggacttcac gggatggtgg tgaattcaag
421 ctggtggatg cagaggaggt ggcccggctg tggggactac gcaagaacaa gaccaacatg
481 aattacgaca agctcagccg ggccttgcgg tactactatg acaagaacat catccgcaag
541 gtgagcggcc agaagttcgt ctacaagttt gtgtcctacc ctgaggtcgc agggtgctcc
601 actgaggact gcccgcccca gccagaggtg tctgttacct ccaccatgcc aaatgtggcc
661 cctgctgcta tacatgccgc cccaggggac actgtctctg gaaagccagg cacacccaag
721 ggtgcaggaa tggcaggccc aggcggtttg gcacgcagca gccggaacga gtacatgcgc
781 tcgggcctct attccacctt caccatccag tctctgcagc cgcagccacc ccctcatcct
841 cggcctgctg tggtgctccc caatgcagct cctgcagggg cagcagcgcc cccctcgggg
901 agcaggagca ccagtccaag ccccttggag gcctgtctgg aggctgaaga ggccggcttg
961 cctctgcagg tcatcctgac cccgcccgag gccccaaacc tgaaatcgga agagcttaat
1021 gtggagccgg gtttgggccg ggctttgccc ccagaagtga aagtagaagg gcccaaggaa
1081 gagttggaag ttgcggggga gagagggttt gtgccagaaa ccaccaaggc cgagccagaa
1141 gtccctccac aggagggcgt gccagcccgg ctgcccgcgg ttgttatgga caccgcaggg
1201 caggcgggcg gccatgcggc ttccagccct gagatctccc agccgcagaa gggccggaag
1261 ccccgggacc tagagcttcc actcagcccg agcctgctag gtgggccggg acccgaacgg
1321 accccaggat cgggaagtgg ctccggcctc caggctccgg ggccggcgct gaccccatcc
1381 ctgcttccta cgcatacatt gaccccggtg ctgctgacac ccagctcgct gcctcctagc
1441 attcacttct ggagcaccct gagtcccatt gcgccccgta gcccggccaa gctctccttc
1501 cagtttccat ccagtggcag cgcccaggtg cacatccctt ctatcagcgt ggatggcctc
1561 tcgacccccg tggtgctctc cccagggccc cagaagccat gactactacc accaccacca
1621 ccaccccttc tggggtcact ccatccatgc tctctccagc cagccatctc aaggagaaac
1681 atagttcaac tgaaagactc atgctctgat tgtggtgggg tggggatcct tgggaagaat
1741 tactcccaag agtaactctc attatctcct ccacagaaaa cacacagctt ccacaacttc
1801 tctgttttct gtcagtcccc cagtggccgc ccttacacgt ctcctacttc aatggtaggg
1861 gcggtttatt tatttatttt ttgaaggcca ctgggatgag cctgacctaa ccttttaggg
1921 tggttaggac atctccccca cctccccact tttttcccca agacaagaca atcgaggtct
1981 ggcttgagaa cgacctttct ttctttattt ctcagcctgc ccttggggag atgagggagc
2041 cctgtctgcg tttttggatg tgagtagaag agttagtttg ttttgtttta ttattcctgg
2101 ccatactcag gggtccagga agaatttgta ccatttaatg ggttgggagt cttggccaag
2161 gaagaatcac acccttggaa tagaaatttc cacctccccc aacctttctc tcagacagct
2221 tatccttttt caaccaactt tttggccagg gaggaatgtc cctttt
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