LOCUS HUMLOX15A 2671 bp mRNA linear HUM 11-JUN-1993
DEFINITION Human 15-lipoxygenase mRNA, complete cds.
ACCESSION M23892
VERSION M23892.1
KEYWORDS 15-lipoxygenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2671)
AUTHORS Sigal,E., Craik,C.S., Highland,E., Grunberger,D., Costello,L.L.,
Dixon,R.A. and Nadel,J.A.
TITLE Molecular cloning and primary structure of human 15-lipoxygenase
JOURNAL Biochem. Biophys. Res. Commun. 157 (2), 457-464 (1988)
PUBMED 3202857
COMMENT Original source text: Human reticulocyte, cDNA to mRNA, clone
15LOX.
FEATURES Location/Qualifiers
source 1..2671
/db_xref="H-InvDB:HIT000194905"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..2671
/product="15-lipoxygenase mRNA"
CDS 4..1992
/note="15-lipoxygenase"
/codon_start=1
/protein_id="AAA36182.1"
/translation="MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARG
KETELKVEVPEYLGPLLFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEG
NGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDL
PVDERFLEDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERV
RDSWKEDALFGYQFLNGANPVVLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEA
DFSLLDGIKANVILCSQQHLAAPLVMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPT
DPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPH
LRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADR
GLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQ
GAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPP
TTKDATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLK
KFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI"
BASE COUNT 580 a 743 c 718 g 630 t
ORIGIN
1 aagatgggtc tctaccgcat ccgcgtgtcc actggggcct cgctctatgc cggttccaac
61 aaccaggtgc agctgtggct ggtcggccag cacggggagg cggcgctcgg gaagcgactg
121 tggcccgcac ggggcaagga gacagaactc aaggtggaag taccggagta tctggggccg
181 ctgctgtttg tgaaactgcg caaacggcac ctccttaagg acgacgcctg gttctgcaac
241 tggatctctg tgcagggccc cggagccggg gacgaggtca ggttcccttg ttaccgctgg
301 gtggagggca acggcgtcct gagcctgcct gaaggcaccg gccgcactgt gggcgaggac
361 cctcagggcc tgttccagaa acaccgggaa gaagagctgg aagagagaag gaagttgtac
421 cggtggggaa actggaagga cgggttaatt ctgaatatgg ctggggccaa actatatgac
481 ctccctgtgg atgagcgatt tctggaagac aagagagttg actttgaggt ttcgctggcc
541 aaggggctgg ccgacctcgc tatcaaagac tctctaaatg ttctgacttg ctggaaggat
601 ctagatgact tcaaccggat tttctggtgt ggtcagagca agctggctga gcgcgtgcgg
661 gactcctgga aggaagatgc cttatttggg taccagtttc ttaatggcgc caaccccgtg
721 gtgctgaggc gctctgctca ccttcctgct cgcctagtgt tccctccagg catggaggaa
781 ctgcaggccc agctggagaa ggagctggag ggaggcacac tgttcgaagc tgacttctcc
841 ctgctggatg ggatcaaggc caacgtcatt ctctgtagcc agcagcacct ggctgcccct
901 ctagtcatgc tgaaattgca gcctgatggg aaactcttgc ccatggtcat ccagctccag
961 ctgccccgca caggatcccc accacctccc cttttcttgc ctacggatcc cccaatggcc
1021 tggcttctgg ccaaatgctg ggtgcgcagc tctgacttcc agctccatga gctgcagtct
1081 catcttctga ggggacactt gatggctgag gtcattgttg tggccaccat gaggtgcctg
1141 ccgtcgatac atcctatctt caagcttata attccccacc tgcgatacac cctggaaatt
1201 aacgtccggg ccaggactgg gctggtctct gacatgggaa ttttcgacca gataatgagc
1261 actggtgggg gaggccacgt gcagctgctc aagcaagctg gagccttcct aacctacagc
1321 tccttctgtc cccctgatga cttggccgac cgggggctcc tgggagtgaa gtcttccttc
1381 tatgcccaag atgcgctgcg gctctgggaa atcatctatc ggtatgtgga aggaatcgtg
1441 agtctccact ataagacaga cgtggctgtg aaagacgacc cagagctgca gacctggtgt
1501 cgagagatca ctgaaatcgg gctgcaaggg gcccaggacc gagggtttcc tgtctcttta
1561 caggctcggg accaggtttg ccactttgtc accatgtgta tcttcacctg caccggccaa
1621 cacgcctctg tgcacctggg ccagctggac tggtactctt gggtgcctaa tgcaccctgc
1681 acgatgcggc tgcccccgcc aaccaccaag gatgcaacgc tggagacagt gatggcgaca
1741 ctgcccaact tccaccaggc ttctctccag atgtccatca cttggcagct gggcagacgc
1801 cagcccgtta tggtggctgt gggccagcat gaggaggagt atttttcggg ccctgagcct
1861 aaggctgtgc tgaagaagtt cagggaggag ctggctgccc tggataagga aattgagatc
1921 cggaatgcaa agctggacat gccctacgag tacctgcggc ccagcgtggt ggaaaacagt
1981 gtggccatct aagcgtcgcc accctttggt tatttcagcc cccatcaccc aagccacaag
2041 ctgacccctt cgtggttata gccctgccct cccaagtccc accctcttcc catgtcccac
2101 cctccctaga ggggcacctt ttcatggtct ctgcacccag tgaacacatt ttactctaga
2161 ggcatcacct gggaccttac tcctctttcc ttccttcctc ctttcctatc ttccttcctc
2221 tctctcttcc tctttcttca ttcagatcta tatggcaaat agccacaatt atataaatca
2281 tttcaagact agaatagggg gatataatac atattactcc acacctttta tgaatcaaat
2341 atgatttttt tgttgttgtt aagacagagt ctcactttga cacccaggct ggagtgcagt
2401 ggtgccatca ccacggctca ctgcagcctc agcgtcctgg gctcaaatga tcctcccacc
2461 tcagcctcct gagtagctgg gactacaggc tcatgccatc atgcccagct aatatttttt
2521 tattttcgtg gagacggggc ctcactatgt tgcctaggct ggaaatagga ttttgaaccc
2581 aaattgagtt taacaataat aaaaagttgt tttacgctaa agatggaaaa gaactaggac
2641 tgaactattt taaataaaat attggcaaaa g
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