LOCUS RATPIT1Z 1548 bp mRNA linear ROD 20-JUL-1994
DEFINITION Rat pituitary-specific positive transcription factor (Pit-1) mRNA,
complete cds.
ACCESSION M23253
VERSION M23253.1
KEYWORDS transcription factor.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 1548)
AUTHORS Ingraham,H.A., Chen,R.P., Mangalam,H.J., Elsholtz,H.P., Flynn,S.E.,
Lin,C.R., Simmons,D.M., Swanson,L. and Rosenfeld,M.G.
TITLE A tissue-specific transcription factor containing a homeodomain
specifies a pituitary phenotype
JOURNAL Cell 55 (3), 519-529 (1988)
PUBMED 2902928
COMMENT On Jul 21, 1994 this sequence version replaced gi:340856.
Original source text: Rattus norvegicus pituitary cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1548
/organism="Rattus norvegicus"
/mol_type="mRNA"
/db_xref="taxon:10116"
/cell_line="G/C"
/tissue_type="pituitary"
gene 1..1548
/gene="Pit-1"
CDS 31..906
/gene="Pit-1"
/note="pituitary-specific positive"
/codon_start=1
/product="transcription factor"
/protein_id="AAA41854.1"
/translation="MSCQPFTSADTFIPLNSDASAALPLRMHHSAAEGLPASNHATNV
MSTATGLHYSVPSCHYGNQPSTYGVMAGTLTPCLYKFPDHTLSHGFPPLHQPLLAEDP
TASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAV
HGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRR
TTISIAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSL
NQSLFSISKEHLECR"
misc_feature 670..849
/gene="Pit-1"
/note="sequence homologous to the homeodomains of
Drosophila trans-acting factors."
BASE COUNT 456 a 349 c 330 g 413 t
ORIGIN
1 tggctcttag ttctctactc tcttgtggga atgagttgcc aacctttcac ctcggctgat
61 acctttatac ctctgaattc tgacgcttct gctgccctgc ctctgagaat gcaccacagt
121 gccgctgagg gtctcccagc ctccaaccac gccaccaacg tgatgtccac agcgacagga
181 cttcattatt ctgtgccttc ctgtcattat ggaaaccagc catccaccta cggagtgatg
241 gcaggcactt taaccccttg tctttacaag tttccagacc acaccctgag tcatgggttt
301 cctcccctgc accaacctct gctggcggag gacccaacag cctctgaatt taagcaggaa
361 ctcaggcgga aaagtaaatt ggtggaagag ccaatagaca tggactcccc ggaaatccga
421 gaactggagc agtttgccaa cgaatttaaa gtgagaagaa ttaagttagg atacacccag
481 acaaacgtgg gcgaagctct ggccgctgtc cacggctccg aattcagtca aacaaccatc
541 tgccgatttg aaaacttgca gctcagtttc aaaaatgctt gcaaactgaa agcaatttta
601 tccaagtggc tggaggaagc tgagcaggtc ggagctttgt acaatgaaaa agtgggagca
661 aacgaaagga agaggaaacg gaggacaact atcagtatcg ccgctaagga tgctttggag
721 agacactttg gagagcacag caaaccttct tcgcaggaga tcatgcggat ggctgaagaa
781 ttgaatctcg agaaagaagt agtaagagtg tggttttgca accgaaggca gagagaaaaa
841 cgggtgaaaa cgagtctcaa tcaaagtctg ttctctattt caaaggagca tcttgagtgc
901 agataagact tgcctgtggt agccatgtgt ggtagccttt ccattccttt ctgatttcaa
961 gaaaaatcag aagttactta gcttcataaa ctagattaaa tcagcaaccc ctgcagtttt
1021 tgtttcactt tctttctttc ctttttagat ccaatgattt aaaacaagac gttttattta
1081 gttgttctca gaattcatag cattgccttt actcctaaat catcaccaag aatgctcaca
1141 atacctcttc caattctgcc tttataccta atacacagag aggtggggat aactgggaga
1201 gaggccatca tatatgtgaa tatttgagtt taaaattacc ttttgtaagt caatttattg
1261 ttctttaaat tttaatcagt aaggatcaaa tatttaccga ctattaacca gggatggctc
1321 aagttgataa tctattgact tggccagaga gatgtctcag cggttaagag catctgttgc
1381 tcttccagag gatgtgggtt ccatcaccta tacagctcac aactgtctgt cacactattc
1441 cagaggaaat ccaaggagtc tcctgggttc cattgacact tggcctgaaa atggagcaca
1501 gacatacatg tagacaaaat actcatacat atacagtaaa aataataa
//