LOCUS HUMCD33DA 1437 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human differentiation antigen (CD33) mRNA, complete cds.
ACCESSION M23197
VERSION M23197.1
KEYWORDS differentiation antigen CD33.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1437)
AUTHORS Simmons,D. and Seed,B.
TITLE Isolation of a cDNA encoding CD33, a differentiation antigen of
myeloid progenitor cells
JOURNAL J. Immunol. 141 (8), 2797-2800 (1988)
PUBMED 3139766
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1437
/db_xref="H-InvDB:HIT000194879"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19q13.3"
/cell_line="U937"
/lab_host="COS cell"
gene 1..1437
/gene="CD33"
CDS 13..1107
/gene="CD33"
/codon_start=1
/product="differentiation antigen"
/protein_id="AAA51948.1"
/db_xref="GDB:G00-119-762"
/translation="MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFF
HPIPYYDKNSPVHGYWFREGAIISGDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCS
LSIVDARRRDNGSYFFRMERGSTKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKN
LTCSVSWACEQGTPPIFSWLSAAPTSLGPRTTHSSVLIITPRPQDHGTNLTCQVKFAG
AGVTTERTIQLNVTYVPQNPTTGIFPGDGSGKQETRAGLVHGAIGGAGVTALLALCLC
LIFFIVKTHRRKAARTAVGSNDTHPTTGSASPKHQKNSKLHGPTETSSCSGAAPTVEM
DEELHYASLNFHGMNPSKDTSTEYSEVRTQ"
regulatory 1411..1416
/regulatory_class="polyA_signal_sequence"
/gene="CD33"
/note="G00-119-762"
polyA_site 1437
/gene="CD33"
/note="G00-119-762"
BASE COUNT 360 a 412 c 343 g 322 t
ORIGIN Chromosome 19q13.3.
1 gcttcctcag acatgccgct gctgctactg ctgcccctgc tgtgggcagg ggccctggct
61 atggatccaa atttctggct gcaagtgcag gagtcagtga cggtacagga gggtttgtgc
121 gtcctcgtgc cctgcacttt cttccatccc ataccctact acgacaagaa ctccccagtt
181 catggttact ggttccggga aggagccatt atatccgggg actctccagt ggccacaaac
241 aagctagatc aagaagtaca ggaggagact cagggcagat tccgcctcct tggggatccc
301 agtaggaaca actgctccct gagcatcgta gacgccagga ggagggataa tggttcatac
361 ttctttcgga tggagagagg aagtaccaaa tacagttaca aatctcccca gctctctgtg
421 catgtgacag acttgaccca caggcccaaa atcctcatcc ctggcactct agaacccggc
481 cactccaaaa accttacctg ctctgtgtcc tgggcctgtg agcagggaac acccccgatc
541 ttctcctggt tgtcagctgc ccccacctcc ctgggcccca ggactactca ctcctcggtg
601 ctcataatca ccccacggcc ccaggaccac ggcaccaacc tgacctgtca ggtgaagttc
661 gctggagctg gtgtgactac ggagagaacc atccagctca acgtcaccta tgttccacag
721 aacccaacaa ctggtatctt tccaggagat ggctcaggga aacaagagac cagagcagga
781 ctggttcatg gggccattgg aggagctggt gttacagccc tgctcgctct ttgtctctgc
841 ctcatcttct tcatagtgaa gacccacagg aggaaagcag ccaggacagc agtgggcagc
901 aatgacaccc accctaccac agggtcagcc tccccgaaac accagaagaa ctccaagtta
961 catggcccca ctgaaacctc aagctgttca ggtgccgccc ctactgtgga gatggatgag
1021 gagctgcatt atgcttccct caactttcat gggatgaatc cttccaagga cacctccacc
1081 gaatactcag aggtcaggac ccagtgagga accctcaaga gcatcaggct cagctagaag
1141 atccacatcc tctacaggtc ggggaccaaa ggctgattct tggagattta actccccaca
1201 ggcaatgggt ttatagacat tatgtgagtt tcctgctata ttaacatcat cttgagactt
1261 tgcaagcaga gagtcgtgga atcaaatctg tgctctttca tttgctaagt gtatgatgtc
1321 acacaagctc cttaaccttc catgtctcca ttttcttctc tgtgaagtag gtataagaag
1381 tcctatctca tagggatgct gtgagcatta aataaaggta cacatggaaa acaccag
//