LOCUS HUMBGAL 2379 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human beta-galactosidase (GLB1) mRNA, complete cds.
ACCESSION M22590
VERSION M22590.1
KEYWORDS beta-galactosidase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2379)
AUTHORS Oshima,A., Tsuji,A., Nagao,Y., Sakuraba,H. and Suzuki,Y.
TITLE Cloning, sequencing, and expression of cDNA for human
beta-galactosidase
JOURNAL Biochem. Biophys. Res. Commun. 157 (1), 238-244 (1988)
PUBMED 3143362
COMMENT Original source text: Human placenta (library of J.E.Saddler), cDNA
to mRNA, clone GP8.
Draft entry and sequence for [1] kindly submitted by A.Oshima,
16-FEB-1989.
FEATURES Location/Qualifiers
source 1..2379
/db_xref="H-InvDB:HIT000194850"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="3p23-p22"
gene 1..2379
/gene="GLB1"
CDS 35..2068
/gene="GLB1"
/note="beta-galactosidase precursor (EC 3.2.1.23)"
/codon_start=1
/protein_id="AAA51822.1"
/db_xref="GDB:G00-119-987"
/translation="MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKD
GQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDH
DVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDK
WLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLAFLQKRFRHHLGDDVVLF
TTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDH
WGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYD
APLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDIL
CPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGI
PQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTD
WTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLP
QDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWA
PCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV"
sig_peptide 35..103
/gene="GLB1"
/note="beta-galactosidase signal peptide"
mat_peptide 104..2065
/gene="GLB1"
/product="beta-galactosidase"
BASE COUNT 561 a 625 c 601 g 592 t
ORIGIN Unreported.
1 gggcgccgac tgcagagccg ggaggctggt ggtcatgccg gggttcctgg ttcgcatcct
61 ccctctgttg ctggttctgc tgcttctggg ccctacgcgc ggcttgcgca atgccaccca
121 gaggatgttt gaaattgact atagccggga ctccttcctc aaggatggcc agccatttcg
181 ctacatctca ggaagcattc actactcccg tgtgccccgc ttctactgga aggaccggct
241 gctgaagatg aagatggctg ggctgaacgc catccagacg tatgtgccct ggaactttca
301 tgagccctgg ccaggacagt accagttttc tgaggaccat gatgtggaat attttcttcg
361 gctggctcat gagctgggac tgctggttat cctgaggccc gggccctaca tctgtgcaga
421 gtgggaaatg ggaggattac ctgcttggct gctagagaaa gagtctattc ttctccgctc
481 ctccgaccca gattacctgg cagctgtgga caagtggttg ggagtccttc tgcccaagat
541 gaagcctctc ctctatcaga atggagggcc agttataaca gtgcaggttg aaaatgaata
601 tggcagctac tttgcctgtg attttgacta cctcgcgttc ctgcagaagc gctttcgcca
661 ccatctgggg gatgatgtgg ttctgtttac cactgatgga gcacataaaa cattcctgaa
721 atgtggggcc ctgcagggcc tctacaccac ggtggacttt ggaacaggca gcaacatcac
781 agatgctttc ctaagccaga ggaagtgtga gcccaaagga cccttgatca attctgaatt
841 ctatactggc tggctagatc actggggcca acctcactcc acaatcaaga ccgaagcagt
901 ggcttcctcc ctctatgata tacttgcccg tggggcgagt gtgaacttgt acatgtttat
961 aggtgggacc aattttgcct attggaatgg ggccaactca ccctatgcag cacagcccac
1021 cagctacgac tatgatgccc cactgagtga ggctggggac ctcactgaga agtattttgc
1081 tctgcgaaac atcatccaga agtttgaaaa agtaccagaa ggtcctatcc ctccatctac
1141 accaaagttt gcatatggaa aggtcacttt ggaaaagtta aagacagtgg gagcagctct
1201 ggacattctg tgtccctctg ggcccatcaa aagcctttat cccttgacat ttatccaggt
1261 gaaacagcat tatgggtttg tgctgtaccg gacaacactt cctcaagatt gcagcaaccc
1321 agcacctctc tcttcacccc tcaatggagt ccacgatcga gcatatgttg ctgtggatgg
1381 gatcccccag ggagtccttg agcgaaacaa tgtgatcact ctgaacataa cagggaaagc
1441 tggagccact ctggaccttc tggtagagaa catgggacgt gtgaactatg gtgcatatat
1501 caacgatttt aagggtttgg tttctaacct gactctcagt tccaatatcc tcacggactg
1561 gacgatcttt ccactggaca ctgaggatgc agtgcgcagc cacctggggg gctggggaca
1621 ccgtgacagt ggccaccatg atgaagcctg ggcccacaac tcatccaact acacgctccc
1681 ggccttttat atggggaact tctccattcc cagtgggatc ccagacttgc cccaggacac
1741 ctttatccag tttcctggat ggaccaaggg ccaggtctgg attaatggct ttaaccttgg
1801 ccgctattgg ccagcccggg gccctcagtt gaccttgttt gtgccccagc acatcctgat
1861 gacctcggcc ccaaacacca tcaccgtgct ggaactggag tgggcaccct gcagcagtga
1921 tgatccagaa ctatgtgctg tgacgttcgt ggacaggcca gttattggct catctgtgac
1981 ctacgatcat ccctccaaac ctgttgaaaa aagactcatg cccccacccc cgcaaaaaaa
2041 caaagattca tggctggacc atgtatgatg atgaaagcct gtgtctttga gggattctac
2101 cctgaactaa cctcacagat cctccctgtc atgccacatt tcactgattg gaatgtggaa
2161 atggaaaagg aatttaggat gtgcattttc acctgaggtt tccctgcatc cctgcagtgc
2221 caaagcccca ccttcaggga ccacctggaa tgtgtgaggg gctgacagca cagtaacgtg
2281 catacatatc tgcagggctg gaatggaagc tttaaaggtg gtagtgattt ttattttgga
2341 agaatcatgt tacctttttg ttaaataaaa tttgtactc
//