LOCUS HUMIHRP 1682 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human placental ribonuclease inhibitor mRNA, complete cds.
ACCESSION M22414
VERSION M22414.1
KEYWORDS ribonuclease inhibitor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1682)
AUTHORS Lee,F.S., Fox,E.A., Zhou,H.M., Strydom,D.J. and Vallee,B.L.
TITLE Primary structure of human placental ribonuclease inhibitor
JOURNAL Biochemistry 27 (23), 8545-8553 (1988)
PUBMED 3219362
COMMENT Original source text: Human placenta, cDNA to mRNA, clones
lambda-PRI-[A,I,F].
Draft entry and computer-readable sequence for [1] kindly provided
by F.S. Lee, 08-FEB-1989.
FEATURES Location/Qualifiers
source 1..1682
/db_xref="H-InvDB:HIT000194839"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="11p15.5"
gene 1..1682
/gene="RNH"
mRNA <1..1682
/gene="RNH"
/note="INR mRNA; G00-125-274"
CDS 122..1507
/gene="RNH"
/note="ribonuclease inhibitor precursor"
/codon_start=1
/protein_id="AAA59130.1"
/translation="MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEAR
CKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGC
GVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCE
PLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD
LCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDL
CRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFS
SVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAA
TLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQAL
EKDKPSLRVIS"
mat_peptide 125..1504
/gene="RNH"
/product="ribonuclease inhibitor"
BASE COUNT 300 a 535 c 535 g 312 t
ORIGIN 10 bp upstream of HincII site.
1 cggggttgtc gacacgttca acccgttctg ctggctcgag aacgaagtag gccgtctcgc
61 tctgggtctc caggcccgcg accgtccgcc agtcgtcccg aggccactct tcacctccac
121 catgagcctg gacatccaga gcctggacat ccagtgtgag gagctgagcg acgctagatg
181 ggccgagctc ctccctctgc tccagcagtg ccaagtggtc aggctggacg actgtggcct
241 cacggaagca cggtgcaagg acatcagctc tgcacttcga gtcaaccctg cactggcaga
301 gctcaacctg cgcagcaacg agctgggcga tgtcggcgtg cattgcgtgc tccagggcct
361 gcagaccccc tcctgcaaga tccagaagct gagcctccag aactgctgcc tgacgggggc
421 cggctgcggg gtcctgtcca gcacactacg caccctgccc accctgcagg agctgcacct
481 cagcgacaac ctcttggggg atgcgggcct gcagctgctc tgcgaaggac tcctggaccc
541 ccagtgccgc ctggaaaagc tgcagctgga gtattgcagc ctctcggctg ccagctgcga
601 gcccctggcc tccgtgctca gggccaagcc ggacttcaag gagctcacgg ttagcaacaa
661 cgacatcaat gaggctggcg tccgtgtgct gtgccagggc ctgaaggact ccccctgcca
721 gctggaggcg ctcaagctgg agagctgcgg tgtgacatca gacaactgcc gggacctgtg
781 cggcattgtg gcctccaagg cctcgctgcg ggagctggcc ctgggcagca acaagctggg
841 tgatgtgggc atggcggagc tgtgcccagg gctgctccac cccagctcca ggctcaggac
901 cctgtggatc tgggagtgtg gcatcactgc caagggctgc ggggatctgt gccgtgtcct
961 cagggccaag gagagcctga aggagctcag cctggccggc aacgagctgg gggatgaggg
1021 tgcccgactg ctgtgtgaga ccctgctgga acctggctgc cagctggagt cgctgtgggt
1081 gaagtcctgc agcttcacag ccgcctgctg ctcccacttc agctcagtgc tggcccagaa
1141 caggtttctc ctggagctac agataagcaa caacaggctg gaggatgcgg gcgtgcggga
1201 gctgtgccag ggcctgggcc agcctggctc tgtgctgcgg gtgctctggt tggccgactg
1261 cgatgtgagt gacagcagct gcagcagcct cgccgcaacc ctgttggcca accacagcct
1321 gcgtgagctg gacctcagca acaactgcct gggggacgcc ggcatcctgc agctggtgga
1381 gagcgtccgg cagccgggct gcctcctgga gcagctggtc ctgtacgaca tttactggtc
1441 tgaggagatg gaggaccggc tgcaggccct ggagaaggac aagccatccc tgagggtcat
1501 ctcctgaggc tcttcctgct gctgctctcc ctggacgacc ggcctcgagg caaccctggg
1561 gcccaccagc ccctgccatg ctctcaccct gcatatccta ggtttgaaga gaaacgctca
1621 gatccgctta tttctgccag tatattttgg acactttata atcattaaag cactttcttg
1681 gc
//