LOCUS HUMENOG 2274 bp mRNA linear HUM 22-AUG-1995
DEFINITION Human neuron-specific gamma-2 enolase, complete cds.
ACCESSION M22349 M27833
VERSION M22349.1
KEYWORDS 2-phospho-D-glycerate hydrolase; acidic cytoplasmic protein;
enolase; gamma-2 enolase; glycolytic enzyme; neuron-specific
isoform.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2274)
AUTHORS Oliva,D., Barba,G., Barbieri,G., Giallongo,A. and Feo,S.
TITLE Cloning, expression and sequence homologies of cDNA for human gamma
enolase
JOURNAL Gene 79 (2), 355-360 (1989)
PUBMED 2792767
REFERENCE 2 (sites)
AUTHORS Feo,S.
TITLE Sequence update
JOURNAL Unpublished
COMMENT On Aug 23, 1995 this sequence version replaced gi:182115.
Original source text: Homo sapiens (clone: B6, L40) brain cDNA to
mRNA.
Draft entry and computer-readable sequence [1] kindly submitted by
S.Feo, 23-JAN-1989.
FEATURES Location/Qualifiers
source 1..2274
/db_xref="H-InvDB:HIT000194834"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12p13"
/clone="B6, L40"
/cell_line="neuroblastoma IMR-32"
/tissue_type="brain"
/germline
gene 1..2274
/gene="ENO2"
old_sequence 2
/gene="ENO2"
/citation=[2]
/replace="g"
CDS 75..1379
/gene="ENO2"
/EC_number="4.2.1.11"
/standard_name="gamma-2 enolase"
/codon_start=1
/product="enolase"
/protein_id="AAB59554.1"
/db_xref="GDB:G00-119-872"
/translation="MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIY
EALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTEN
KSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAG
NKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNIL
ENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQL
GALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEE
KACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQ
IKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL"
old_sequence 1457..1460
/gene="ENO2"
/citation=[2]
/replace="ccc"
BASE COUNT 487 a 597 c 626 g 564 t
ORIGIN
1 gcgccgccgt cgccaccgcc accgccaccg ccactaccac cgtctgagtc tgcagtcccg
61 agatcccagc catcatgtcc atagagaaga tctgggcccg ggagatcctg gactcccgcg
121 ggaaccccac agtggaggtg gatctctata ctgccaaagg tcttttccgg gctgcagtgc
181 ccagtggagc ctctacgggc atctatgagg ccctggagct gagggatgga gacaaacagc
241 gttacttagg caaaggtgtc ctgaaggcag tggaccacat caactccacc atcgcgccag
301 ccctcatcag ctcaggtctc tctgtggtgg agcaagagaa actggacaac ctgatgctgg
361 agttggatgg gactgagaac aaatccaagt ttggggccaa tgccatcctg ggtgtgtctc
421 tggccgtgtg taaggcaggg gcagctgagc gggaactgcc cctgtatcgc cacattgctc
481 agctggccgg gaactcagac ctcatcctgc ctgtgccggc cttcaacgtg atcaatggtg
541 gctctcatgc tggcaacaag ctggccatgc aggagttcat gatcctccca gtgggagctg
601 agagctttcg ggatgccatg cgactaggtg cagaggtcta ccatacactc aagggagtca
661 tcaaggacaa atacggcaag gatgccacca atgtggggga tgaaggtggc tttgccccca
721 atatcctgga gaacagtgaa gccttggagc tggtgaagga agccatcgac aaggctggct
781 acacggaaaa gatcgttatt ggcatggatg ttgctgcctc agagttttat cgtgatggca
841 aatatgactt ggacttcaag tctcccactg atccttcccg atacatcact ggggaccagc
901 tgggggcact ctaccaggac tttgtcaggg actatcctgt ggtctccatt gaggacccat
961 ttgaccagga tgattgggct gcctggtcca agttcacagc caatgtaggg atccagattg
1021 tgggtgatga cctgacagtg accaacccaa aacgtattga gcgggcagtg gaagaaaagg
1081 cctgcaactg tctgctgctc aaggtcaacc agatcggctc ggtcactgaa gccatccaag
1141 cgtgcaagct ggcccaggag aatggctggg gggtcatggt gagtcatcgc tcaggagaga
1201 ctgaggacac attcattgct gacctggtgg tggggctgtg cacaggccag atcaagactg
1261 gtgccccgtg ccgttctgaa cgtctggcta aatacaacca gctcatgaga attgaggaag
1321 agctggggga tgaagctcgc tttgccggac ataacttccg taatcccagt gtgctgtgat
1381 tcctctgctt gcctggagac gtggaacctc tgtctcatcc tcctggaacc ttgctgtcct
1441 gatctgtgat agttcacccc ctgagatccc ctgagcccca gggtgcccag aacttccctg
1501 attgacctgc tccgctgctc cttggcttac ctgacctctt gctgtctctg ctcgccctcc
1561 tttctgtgcc ctactcattg gggttccgca ctttccactt cttcctttct ctttctctct
1621 tccctcagaa actagaaatg tgaatgagga ttattataaa agggggtccg tggaagaatg
1681 atcagcatct gtgatgggag cgtcagggtt ggtgtgctga ggtgttagag agggaccatg
1741 tgtcacttgt gctttgctct tgtcccacgt gtcttccact ttgcatatga gccgtgaact
1801 gtgcatagtg ctgggatgga ggggagtgtt gggcatgtga tcacgcctgg ctaataaggc
1861 tttagtgtat ttatttattt atttatttta tttgtttttc attcatccca ttaatcattt
1921 ccccataact caatggccta aaactggcct gacttggggg aacgatgtgt ctgtatttca
1981 tgtggctgta gatcccaaga tgactggggt gggaggtctt gctagaatgg gaagggtcat
2041 agaaagggcc ttgacatcag ttcctttgtg tgtactcact gaagcctgcg ttggtccaga
2101 gcggaggctg tgtgcctggg ggagttttcc tctatacatc tctccccaac cctaggttcc
2161 ctgttcttcc tccagctgca ccagagcaac ctctcactcc ccatgccacg ttccacagtt
2221 gccaccacct ctgtggcatt gaaatgagca cctccattaa agtctgaatc agtg
//