LOCUS HUMKER2A 2529 bp mRNA linear HUM 11-JUN-1993
DEFINITION Human keratin type II (58 kD) mRNA, complete cds.
ACCESSION M21389
VERSION M21389.1
KEYWORDS epidermal keratin type II; keratin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2529)
AUTHORS Eckert,R.L. and Rorke,E.A.
TITLE The sequence of the human epidermal 58-kD (#5) type II keratin
reveals an absence of 5' upstream sequence conservation between
coexpressed epidermal keratins
JOURNAL DNA 7 (5), 337-345 (1988)
PUBMED 2456903
COMMENT Original source text: Human keratinocytes, cDNA to mRNA,
clonepSP65CS.
FEATURES Location/Qualifiers
source 1..2529
/db_xref="H-InvDB:HIT000194788"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA 295..2529
/product="keratin type II mRNA"
CDS 392..2164
/note="keratin type II"
/codon_start=1
/protein_id="AAA36143.1"
/translation="MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGG
GFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTRGGSFRNRFGAGAGGGYGFGGGAG
SGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPS
IQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPL
FEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLK
KDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLD
LDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEITEMNRM
IQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLL
REYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGY
GGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFG
SGGGSSSSVKFVSTTSSSRKSFKS"
BASE COUNT 565 a 690 c 748 g 526 t
ORIGIN 1304 bp upstream of XmnI site.
1 gcatcctttt tgggctgctc acagccccca gcctctatgg tgaagacata cttgctagca
61 gcgtcaccaa cttgctgcca agagatcagt gctgcaaggc aaggttattt ctaactgagc
121 agagcctgcc aggaagaaag cgtttgcacc ccacaccact gtgcaggtgt gaccggtgag
181 ctcacagctg ccccccaggc atgcccagcc cacttaatca ttcacagctc gacagctctc
241 tcgcccagcc cagttctgga agggataaaa agggggcatc accgttcctg ggtaacagag
301 ccaccttctg cgtcctgctg agctctgttc tctccagcac ctcccaaccc actagtgcct
361 ggttctcttg ctccaccagg aacaagccac catgtctcgc cagtcaagtg tgtccttccg
421 gagcgggggc agtcgtagct tcagcaccgc ctctgccatc accccgtctg tctcccgcac
481 cagcttcacc tccgtgtccc ggtccggggg tggcggtggt ggtggcttcg gcagggtcag
541 ccttgcgggt gcttgtggag tgggtggcta tggcagccgg agcctctaca acctgggggg
601 ctccaagagg atatccatca gcactagagg aggcagcttc aggaaccggt ttggtgctgg
661 tgctggaggc ggctatggct ttggaggtgg tgccggtagt ggatttggtt tcggcggtgg
721 agctggtggt ggctttgggc tcggtggcgg agctggcttt ggaggtggct tcggtggccc
781 tggctttcct gtctgccctc ctggaggtat ccaagaggtc actgtcaacc agagtctcct
841 gactcccctc aacctgcaaa tcgaccccag catccagagg gtgaggaccg aggagcgcga
901 gcagatcaag accctcaaca ataagtttgc ctccttcatc gacaaggtgc ggttcctgga
961 gcagcagaac aaggttctgg acaccaagtg gaccctgctg caggagcagg gcaccaagac
1021 tgtgaggcag aacctggagc cgttgttcga gcagtacatc aacaacctca ggaggcagct
1081 ggacagcatc gtgggggaac ggggccgcct ggactcagag ctgagaaaca tgcaggacct
1141 ggtggaagac ttcaagaaca agtatgagga tgaaatcaac aagcgtacca ctgctgagaa
1201 tgagtttgtg atgctgaaga aggatgtaga tgctgcctac atgaacaagg tggagctgga
1261 ggccaaggtt gatgcactga tggatgagat taacttcatg aagatgttct ttgatgcgga
1321 gctgtcccag atgcagacgc atgtctctga cacctcagtg gtcctctcca tggacaacaa
1381 ccgcaacctg gacctggata gcatcatcgc tgaggtcaag gcccagtatg aggagattgc
1441 caaccgcagc cggacagaag ccgagtcctg gtatcagacc aagtatgagg agctgcagca
1501 gacagctggc cggcatggcg atgacctccg caacaccaag catgagatca cagagatgaa
1561 ccggatgatc cagaggctga gagccgagat tgacaatgtc aagaaacagt gcgccaatct
1621 gcagaacgcc attgcggatg ccgagcagcg tggggagctg gccctcaagg atgccaggaa
1681 caagctggcc gagctggagg aggccctgca gaaggccaag caggacatgg cccggctgct
1741 gcgtgagtac caggagctca tgaacaccaa gctggccctg gacgtggaga tcgccactta
1801 ccgcaagctg ctggagggcg aggaatgcag actcagtgga gaaggagttg gaccagtcaa
1861 catctctgtt gtcacaagca gtgtttcctc tggatatggc agtggcagtg gctatggcgg
1921 tggcctcggt ggaggtcttg gcggcggcct cggtggaggt cttgccggag gtagcagtgg
1981 aagctactac tccagcagca gtgggggtgt cggcctaggt ggtgggctca gtgtgggggg
2041 ctctggcttc agtgcaagca gtggccgagg gctgggggtg ggctttggca gtggcggggg
2101 tagcagctcc agcgtcaaat ttgtctccac cacctcctcc tcccggaaga gcttcaagag
2161 ctaagaacct gctgcaagtc actgccttcc aagtgcagca acccagccca tggagattgc
2221 ctcttctagg cagttgctca agccatgttt tatccttttc tggagagtag tctagaccaa
2281 gccaattgca gaaccacatt ctttggttcc caggagagcc ccattcccag cccctggtct
2341 cccgtgccgc agttctatat tctgcttcaa atcagccttc aggtttccca cagcatggcc
2401 cctgctgaca cgagaaccca aagttttccc aaatctaaat catcaaaaca gaatccccac
2461 cccaatccca aattttgttt tggttctaac tacctccaga atgtgttcaa taaaatgctt
2521 ttataatat
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