LOCUS HUMAMD 1805 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human S-adenosylmethionine decarboxylase mRNA, complete cds.
ACCESSION M21154 J04048
VERSION M21154.1
KEYWORDS AdoMet decarboxylase; S-adenosylmethionine decarboxylase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1805)
AUTHORS Pajunen,A., Crozat,A., Janne,O.A., Ihalainen,R., Laitinen,P.H.,
Stanley,B., Madhubala,R. and Pegg,A.E.
TITLE Structure and regulation of mammalian S-adenosylmethionine
decarboxylase
JOURNAL J. Biol. Chem. 263 (32), 17040-17049 (1988)
PUBMED 2460457
COMMENT Original source text: Human fibroblast, cDNA to mRNA, (library of
Okayama), clone pSAMh1.
Draft entry and computer-readable sequence for [1] kindly provided
by A.Crozat, 27-OCT-1988.
FEATURES Location/Qualifiers
source 1..1805
/db_xref="H-InvDB:HIT000194774"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Xq22-q28"
gene 1..1805
/gene="AMD2"
mRNA <1..1805
/gene="AMD2"
/product="AMD mRNA"
CDS 249..1253
/gene="AMD2"
/note="S-adenosylmethionine decarboxylase proenzyme (EC
4.1.1.50) old gene name 'AMD'"
/codon_start=1
/protein_id="AAA51716.1"
/db_xref="GDB:G00-120-743"
/translation="MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILL
KDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYS
GFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAGYCMGRMNSDCWYLY
TLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVI
DATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFK
PGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
"
BASE COUNT 528 a 344 c 385 g 548 t
ORIGIN 499 bp upstream of KpnI site; chromosome Xq22-q28.
1 aagagactga actgtatctg cctctatttc caaaagactc acgttcaact ttcgctcaca
61 caaagccggg aaaattttat tagtcctttt tttaaaaaaa gttaatataa aattatagca
121 aaaaaaaaaa ggaacctgaa ctttagtaac acagctggaa caatcgcagc ggcggcggca
181 gcggcgggag aagaggttta atttagttga ttttctgtgg ttgttggttg ttcgctagtc
241 tcacggtgat ggaagctgca cattttttcg aagggaccga gaagctgctg gaggtttggt
301 tctcccggca gcagcccgac gcaaaccaag gatctgggga tcttcgcact atcccaagat
361 ctgagtggga catacttttg aaggatgtgc aatgttcaat cataagtgtg acaaaaactg
421 acaagcagga agcttatgta ctcagtgaga gtagcatgtt tgtctccaag agacgtttca
481 ttttgaagac atgtggtacc accctcttgc tgaaagcact ggttcccctg ttgaagcttg
541 ctagggatta cagtgggttt gactcaattc aaagcttctt ttattctcgt aagaatttca
601 tgaagccttc tcaccaaggg tacccacacc ggaatttcca ggaagaaata gagtttctta
661 atgcaatttt cccaaatgga gcaggatatt gtatgggacg tatgaattct gactgttggt
721 acttatatac tctggatttc ccagagagtc gggtaatcag tcagccagat caaaccttgg
781 aaattctgat gagtgagctt gacccagcag ttatggacca gttctacatg aaagatggtg
841 ttactgcaaa ggatgtcact cgtgagagtg gaattcgtga cctgatacca ggttctgtca
901 ttgatgccac aatgttcaat ccttgtgggt attcgatgaa tggaatgaaa tcggatggaa
961 cttattggac tattcacatc actccagaac cagaattttc ttatgttagc tttgaaacaa
1021 acttaagtca gacctcctat gatgacctga tcaggaaagt tgtagaagtc ttcaagccag
1081 gaaaatttgt gaccaccttg tttgttaatc agagttctaa atgtcgcaca gtgcttgctt
1141 cgccccagaa gattgaaggt tttaagcgtc ttgattgcca gagtgctatg ttcaatgatt
1201 acaattttgt ttttaccagt tttgctaaga agcagcaaca acagcagagt tgattaagaa
1261 aaatgaagaa aaaacgcaaa aagagaacac atgtagaagg tggtggatgc tttctagatg
1321 tcgatgctgg gggcagtgct ttccataacc accactgtgt agttgcagaa agccctagat
1381 gtaatgatag tgtaatcatt ttgaattgta tgcattatta tatcaaggag ttagatatct
1441 tgcatgaatg ctctcttctg tgtttaggta ttctctgcca ctcttgctgt gaaattgaag
1501 tggatgtaga aaaaaccttt tactatatga aactttacaa cacttgtgaa agcaactcaa
1561 tttggtttat gcacagtgta atatttctcc aagtatcatc caaaattccc cacagacaag
1621 gctttcgtcc tcattaggtg ttggcctcag cctaaccctc taggactgtt ctattaaatt
1681 gctgccagaa ttttacatcc agttacctcc actttctaga acatattctt tactaatgtt
1741 attgaaacca atttctactt catactgatg tttttggaaa cagcaattaa agtttttctt
1801 ccatg
//