LOCUS HUMPMG3BA 3997 bp mRNA linear HUM 08-JAN-1995
DEFINITION Human platelet membrane glycoprotein IIIa beta subunit mRNA,
complete cds.
ACCESSION M20311
VERSION M20311.1
KEYWORDS cell membrane glycoprotein; platelet membrane glycoprotein IIIa.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3997)
AUTHORS Zimrin,A.B., Eisman,R., Vilaire,G., Schwartz,E., Bennett,J.S. and
Poncz,M.
TITLE Structure of platelet glycoprotein IIIa. A common subunit for two
different membrane receptors
JOURNAL J. Clin. Invest. 81 (5), 1470-1475 (1988)
PUBMED 2452834
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3997
/db_xref="H-InvDB:HIT000194721"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="17q21.32"
/cell_type="erythroleukemia"
gene 1..3997
/gene="ITGB3"
CDS 17..2383
/gene="ITGB3"
/codon_start=1
/product="glycoprotein IIIa"
/protein_id="AAA60122.1"
/db_xref="GDB:G00-120-013"
/translation="MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLA
VSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGD
SSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNL
GTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKH
VLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTT
DAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIF
AVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEEL
SLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDS
LIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQ
QDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHG
QCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTC
EKCPTCPDACTFKKECVECKKFDREPYMTENTCNRYCRDEIESVKELKDTGKDAVNCT
YKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLI
WKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT"
sig_peptide 17..94
/gene="ITGB3"
/note="G00-120-013"
mat_peptide 95..2380
/gene="ITGB3"
/product="glycoprotein IIIa beta subunit"
/note="G00-120-013"
BASE COUNT 917 a 993 c 1099 g 988 t
ORIGIN Chromosome 17.
1 gcgggaggcg gacgagatgc gagcgcggcc gcggccccgg ccgctctggg cgactgtgct
61 ggcgctgggg gcgctggcgg gcgttggcgt aggagggccc aacatctgta ccacgcgagg
121 tgtgagctcc tgccagcagt gcctggctgt gagccccatg tgtgcctggt gctctgatga
181 ggccctgcct ctgggctcac ctcgctgtga cctgaaggag aatctgctga aggataactg
241 tgccccagaa tccatcgagt tcccagtgag tgaggcccga gtactagagg acaggcccct
301 cagcgacaag ggctctggag acagctccca ggtcactcaa gtcagtcccc agaggattgc
361 actccggctc cggccagatg attcgaagaa tttctccatc caagtgcggc aggtggagga
421 ttaccctgtg gacatctact acttgatgga cctgtcttac tccatgaagg atgatctgtg
481 gagcatccag aacctgggta ccaagctggc cacccagatg cgaaagctca ccagtaacct
541 gcggattggc ttcggggcat ttgtggacaa gcctgtgtca ccatacatgt atatctcccc
601 accagaggcc ctcgaaaacc cctgctatga tatgaagacc acctgcttgc ccatgtttgg
661 ctacaaacac gtgctgacgc taactgacca ggtgacccgc ttcaatgagg aagtgaagaa
721 gcagagtgtg tcacggaacc gagatgcccc agagggtggc tttgatgcca tcatgcaggc
781 tacagtctgt gatgaaaaga ttggctggag gaatgatgca tcccacttgc tggtgtttac
841 cactgatgcc aagactcata tagcattgga cggaaggctg gcaggcattg tccagcctaa
901 tgacgggcag tgtcatgttg gtagtgacaa tcattactct gcctccacta ccatggatta
961 tccctctttg gggctgatga ctgagaagct atcccagaaa aacatcaatt tgatctttgc
1021 agtgactgaa aatgtagtca atctctatca gaactatagt gagctcatcc cagggaccac
1081 agttggggtt ctgtccatgg attccagcaa tgtcctccag ctcattgttg atgcttatgg
1141 gaaaatccgt tctaaagtag agctggaagt gcgtgacctc cctgaagagt tgtctctatc
1201 cttcaatgcc acctgcctca acaatgaggt catccctggc ctcaagtctt gtatgggact
1261 caagattgga gacacggtga gcttcagcat tgaggccaag gtgcgaggct gtccccagga
1321 gaaggagaag tcctttacca taaagcccgt gggcttcaag gacagcctga tcgtccaggt
1381 cacctttgat tgtgactgtg cctgccaggc ccaagctgaa cctaatagcc atcgctgcaa
1441 caatggcaat gggacctttg agtgtggggt atgccgttgt gggcctggct ggctgggatc
1501 ccagtgtgag tgctcagagg aggactatcg cccttcccag caggacgaat gcagcccccg
1561 ggagggtcag cccgtctgca gccagcgggg cgagtgcctc tgtggtcaat gtgtctgcca
1621 cagcagtgac tttggcaaga tcacgggcaa gtactgcgag tgtgacgact tctcctgtgt
1681 ccgctacaag ggggagatgt gctcaggcca tggccagtgc agctgtgggg actgcctgtg
1741 tgactccgac tggaccggct actactgcaa ctgtaccacg cgtactgaca cctgcatgtc
1801 cagcaatggg ctgctgtgca gcggccgcgg caagtgtgaa tgtggcagct gtgtctgtat
1861 ccagccgggc tcctatgggg acacctgtga gaagtgcccc acctgcccag atgcctgcac
1921 ctttaagaaa gaatgtgtgg agtgtaagaa gtttgaccgg gagccctaca tgaccgaaaa
1981 tacctgcaac cgttactgcc gtgacgagat tgagtcagtg aaagagctta aggacactgg
2041 caaggatgca gtgaattgta cctataagaa tgaggatgac tgtgtcgtca gattccagta
2101 ctatgaagat tctagtggaa agtccatcct gtatgtggta gaagagccag agtgtcccaa
2161 gggccctgac atcctggtgg tcctgctctc agtgatgggg gccattctgc tcattggcct
2221 tgccgccctg ctcatctgga aactcctcat caccatccac gaccgaaaag aattcgctaa
2281 atttgaggaa gaacgcgcca gagcaaaatg ggacacagcc aacaacccac tgtataaaga
2341 ggccacgtct accttcacca atatcacgta ccggggcact taatgataag cagtcatcct
2401 cagatcatta tcagcctgtg ccacgattgc aggagtccct gccatcatgt ttacagagga
2461 cagtatttgt ggggagggat ttggggctca gagtggggta ggttgggaga atgtcagtat
2521 gtggaagtgt gggtctgtgt gtgtgtatgt gggggtctgt gtgtttatgt gtgtgtgttg
2581 tgtgtgggag tgtgtaattt aaaattgtga tgtgtcctga taagctgagc tccttagcct
2641 ttgtcccaga atgcctcctg cagggattct tcctgcttag cttgagggtg actatggagc
2701 tgagcaggtg ttcttcatta cctcagtgag aagccagctt tcctcatcag gccattgtcc
2761 ctgaagagaa gggcagggct gaggcctctc attccagagg aagggacacc aagccttggc
2821 tctaccctga gttcataaat ttatggttct caggcctgac tctcagcagc tatggtagga
2881 actgctgggc ttggcagccc gggtcatctg tacctctgcc tcctttcccc tccctcaggc
2941 cgaaggagga gtcagggaga gctgaactat tagagctgcc tgtgcctttt gccatcccct
3001 caacccagct atggttctct cgcaagggaa gtccttgcaa gctaattctt tgacctgttg
3061 ggagtgagga tgtctgggcc actcaggggt cattcatggc ctgggggatg taccagcatc
3121 tcccagttca taatcacaac ccttcagatt tgccttattg gcagctctac tctggaggtt
3181 tgtttagaag aagtgtgtca cccttaggcc agcaccatct ctttacctcc taattccaca
3241 ccctcactgc tgtagacatt tgctatgagc tggggatgtc tctcatgacc aaatgctttt
3301 cctcaaaggg agagagtgct attgtagagc cagaggtctg gccctatgct tccggcctcc
3361 tgtccctcat ccatagcacc tccacatacc tggccctgag ccttggtgtg ctgtatccat
3421 ccatggggct gattgtattt accttctacc tcttggctgc cttgtgaagg aattattccc
3481 atgagttggc tgggaataag tgccaggatg gaatgatggg tcagttgtat cagcacgtgt
3541 ggcctgttct tctatgggtt ggacaacctc attttaactc agtctttaat ctgagaggcc
3601 acagtgcaat tttattttat ttttctcatg atgaggtttt cttaacttaa aagaacatgt
3661 atataaacat gcttgcatta tatttgtaaa tttatgtgta tggcaaagaa ggagagcata
3721 ggaaaccaca cagacttggg cagggtacag acactcccac ttggcatcat tcacagcaag
3781 tcactggcca gtggctggat ctgtgagggg ctctctcatg atagaaggct atggggatag
3841 atgtgtggac acattggacc tttcctgagg aagagggact gttcttttgt cccagaaaag
3901 cagtggctcc attggtgttg acatacatcc aacattaaaa gccaccccca aatgcccaag
3961 aaaaaaagaa agacttatca acatttgttc catgagg
//