LOCUS HUMPAP4 1582 bp mRNA linear HUM 11-AUG-1995
DEFINITION Human placenta anticoagulant protein PP4 mRNA, complete cds.
ACCESSION M19384 J03264
VERSION M19384.1
KEYWORDS anticoagulant protein; thromboplastin inhibitor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1582)
AUTHORS Grundmann,U., Abel,K.J., Bohn,H., Lobermann,H., Lottspeich,F. and
Kupper,H.
TITLE Characterization of cDNA encoding human placental anticoagulant
protein (PP4): homology with the lipocortin family
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (11), 3708-3712 (1988)
PUBMED 2967495
COMMENT Original source text: Homo sapiens (clone: PP4-[14,20,26,48].)
placenta cDNA to mRNA.
Draft entry and computer-readable sequence for [1] kindly provided
by U.Grundman, 19-APR-1988.
FEATURES Location/Qualifiers
source 1..1582
/db_xref="H-InvDB:HIT000194688"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="PP4-[14,20,26,48]."
/tissue_type="placenta"
mRNA <1..1582
/product="PP4 mRNA"
CDS 151..1113
/codon_start=1
/product="anticoagulant protein 4"
/protein_id="AAB59545.1"
/translation="MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTS
RSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKG
AGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQAN
RDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISG
FQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSR
SEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD"
variation 214
/note="g in PP4-[14,26,48]; c in PP4-20"
/replace="c"
BASE COUNT 433 a 336 c 364 g 449 t
ORIGIN 82 bp upstream of SmaI site.
1 ctaggtgcag ctgccagatc cttcagcgtc tgcatctcgg cgtcgccccg cgtaccgtcg
61 cccggctctc cgccgctctc ccgggggttc ggggcacttg ggtcccacag tctggtcctg
121 cttcaccttc ccctgacctg agtagtcgct atggcacagg ttctcagagg cactgtgact
181 gacttccctg gatttgatga gcgggctgat gcagaaactc ttcggaaggc tatgaaaggc
241 ttgggcacag atgaggagag catcctgact ctgttgacat cccgaagtaa tgctcagcgc
301 caggaaatct ctgcagcttt taagactctg tttggcaggg atcttctgga tgacctgaaa
361 tcagaactaa ctggaaaatt tgaaaaatta attgtggctc tgatgaaacc ctctcggctt
421 tatgatgctt atgaactgaa acatgccttg aagggagctg gaacaaatga aaaagtactg
481 acagaaatta ttgcttcaag gacacctgaa gaactgagag ccatcaaaca agtttatgaa
541 gaagaatatg gctcaagcct ggaagatgac gtggtggggg acacttcagg gtactaccag
601 cggatgttgg tggttctcct tcaggctaac agagaccctg atgctggaat tgatgaagct
661 caagttgaac aagatgctca ggctttattt caggctggag aacttaaatg ggggacagat
721 gaagaaaagt ttatcaccat ctttggaaca cgaagtgtgt ctcatttgag aaaggtgttt
781 gacaagtaca tgactatatc aggatttcaa attgaggaaa ccattgaccg cgagacttct
841 ggcaatttag agcaactact ccttgctgtt gtgaaatcta ttcgaagtat acctgcctac
901 cttgcagaga ccctctatta tgctatgaag ggagctggga cagatgatca taccctcatc
961 agagtcatgg tttccaggag tgagattgat ctgtttaaca tcaggaagga gtttaggaag
1021 aattttgcca cctctcttta ttccatgatt aagggagata catctgggga ctataagaaa
1081 gctcttctgc tgctctgtgg agaagatgac taacgtgtca cggggaagag ctccctgctg
1141 tgtgcctgca ccaccccact gccttccttc agcaccttta gctgcatttg tatgccagtg
1201 cttaacacat tgccttattc atactagcat gctcatgacc aacacataca cgtcatagaa
1261 gaaaatagtg gtgcttcttt ctgatctcta gtggagatct ctttgactgc tgtagtacta
1321 aagtgtactt aatgttacta agtttaatgc ctggccattt tccatttata tatatttttt
1381 aagaggctag agtgctttta gcctttttta aaaactccat ttatattaca tttgtaacca
1441 tgatacttta atcagaagct tagccttgaa attgtgaact cttggaaatg gtattagtga
1501 agttcgcaac taaactaaac ctgtaaaatt atgatgattg tattcaaaag attaatgaaa
1561 aataaacatt tctgtccccc tg
//