LOCUS HUMACADM 2019 bp mRNA linear HUM 30-OCT-1994
DEFINITION Human medium-chain acyl-CoA dehydrogenase (ACADM) mRNA, complete
cds.
ACCESSION M16827 J05355
VERSION M16827.1
KEYWORDS acyl-CoA dehydrogenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2019)
AUTHORS Kelly,D.P., Kim,J.J., Billadello,J.J., Hainline,B.E., Chu,T.W. and
Strauss,A.W.
TITLE Nucleotide sequence of medium-chain acyl-CoA dehydrogenase mRNA and
its expression in enzyme-deficient human tissue
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (12), 4068-4072 (1987)
PUBMED 3035565
COMMENT Original source text: Human liver (library of S.Woo) and placenta
(library of E.Sadler), cDNA to mRNA, clones M-[2,3].
FEATURES Location/Qualifiers
source 1..2019
/db_xref="H-InvDB:HIT000194484"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1p31"
gene 1..2019
/gene="ACADM"
mRNA <1..2019
/gene="ACADM"
/product="ACADM mRNA"
CDS 19..1284
/gene="ACADM"
/note="medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3)"
/codon_start=1
/protein_id="AAA51566.1"
/db_xref="GDB:G00-118-958"
/translation="MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQ
QKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGT
FDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCV
TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA
FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA
FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR
MSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMR
DAKIYQIYEGTSQIQRLIVAREHIDKYKN"
BASE COUNT 655 a 311 c 425 g 628 t
ORIGIN 46 bp upstream of PstI site; chromosome 1p31.
1 ccggaacgga gagccaacat ggcagcgggg ttcgggcgat gctgcagggt cctgagaagt
61 atttctcgtt ttcattggag atcacagcat acaaaagcca atcgacaacg tgaaccagga
121 ttaggattta gttttgagtt caccgaacag cagaaagaat ttcaagctac tgctcgtaaa
181 tttgccagag aggaaatcat cccagtggct gcagaatatg ataaaactgg tgaatatcca
241 gtccccctaa ttagaagagc ctgggaactt ggtttaatga acacacacat tccagagaac
301 tgtggaggtc ttggacttgg aacttttgat gcttgtttaa ttagtgaaga attggcttat
361 ggatgtacag gggttcagac tgctattgaa ggaaattctt tggggcaaat gcctattatt
421 attgctggaa atgatcaaca aaagaagaag tatttgggga gaatgactga ggagccattg
481 atgtgtgctt attgtgtaac agaacctgga gcaggctctg atgtagctgg tataaagacc
541 aaagcagaaa agaaaggaga tgagtatatt attaatggtc agaagatgtg gataaccaac
601 ggaggaaaag ctaattggta ttttttattg gcacgttctg atccagatcc taaagctcct
661 gctaataaag cctttactgg attcattgtg gaagcagata ccccaggaat tcagattggg
721 agaaaggaat taaacatggg ccagcgatgt tcagatacta gaggaattgt cttcgaagat
781 gtgaaagtgc ctaaagaaaa tgttttaatt ggtgacggag ctggtttcaa agttgcaatg
841 ggagcttttg ataaaaccag acctgtagta gctgctggtg ctgttggatt agcacaaaga
901 gctttggatg aagctaccaa gtatgccctg gaaaggaaaa ctttcggaaa gctacttgta
961 gagcaccaag caatatcatt tatgctggct gaaatggcaa tgaaagttga actagctaga
1021 atgagttacc agagagcagc ttgggaggtt gattctggtc gtcgaaatac ctattatgct
1081 tctattgcaa aggcatttgc tggagatatt gcaaatcagt tagctactga tgctgtgcag
1141 atacttggag gcaatggatt taatacagaa tatcctgtag aaaaactaat gagggatgcc
1201 aaaatctatc agatttatga aggtacttca caaattcaaa gacttattgt agcccgtgaa
1261 cacattgaca agtacaaaaa ttaaaaaaat tactgtagaa atattgaata actagaacac
1321 aagccactgt ttcagctcca gaaaaaagaa agggctttaa cgttttttcc agtgaaaaca
1381 aatcctctta tattaaatct aagcaactgc ttattatagt agtttatact tttgcttaac
1441 tctgttatgt ctcttaagca ggtttggttt ttattaaaat gatgtgtttt ctttagtacc
1501 actttacttg aattacatta acctagaaaa ctacataggt tattttgatc tcttaagatt
1561 aatgtagcag aaatttcttg gaattttatt tttgtaatga cagaaaagtg ggcttagaaa
1621 gtattcaaga tgttacaaaa tttacattta gaaaatattg tagtatttga atactgtcaa
1681 cttgacagta actttgtaga cttaatggta ttattaaagt tctttttatt gcagtttgga
1741 aagcatttgt gaaactttct gtttggcaca gaaacagtca aaattttgac attcatattc
1801 tcctatttta cagctacaag aactttcttg aaaatcttat ttaattctga gcccatattt
1861 cacttacctt atttaaaata aatcaataaa gcttgcctta aattattttt atatgactgt
1921 tggtctctag gtagcctttg gtctattgta cacaatctca tttcatatgt ttgcattttg
1981 gcaaagaact taataaaatt gttcagtgct tattatcat
//