LOCUS HUMALPHB 1587 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human adult intestinal phosphatase type, complete cds.
ACCESSION M15694
VERSION M15694.1
KEYWORDS adult intestinal phosphatase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1587)
AUTHORS Henthorn,P.S., Raducha,M., Edwards,Y.H., Weiss,M.J., Slaughter,C.,
Lafferty,M.A. and Harris,H.
TITLE Nucleotide and amino acid sequences of human intestinal alkaline
phosphatase: close homology to placental alkaline phosphatase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (5), 1234-1238 (1987)
PUBMED 3469665
COMMENT Original source text: Human adult intestinal phosphatase (ALP),
cDNA to mRNA, clone D98/AH-2.
FEATURES Location/Qualifiers
source 1..1587
/db_xref="H-InvDB:HIT000194411"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="2q34-q37"
gene 1..1587
/gene="ALPI"
CDS 1..1587
/gene="ALPI"
/note="adult intestinal phosphatase (EC 3.1.3.1)"
/codon_start=1
/protein_id="AAA51703.1"
/db_xref="GDB:G00-119-671"
/translation="MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKK
LQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTY
NVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGK
SVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVI
LGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQAS
LDQSVTHLMGLFEPGDTKYEILRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRI
DHGHHEGVAYQAVTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSS
IFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSET
HGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLALPACTTDAAHPV
AASLPLLAGTLLLLGASAAP"
BASE COUNT 317 a 515 c 490 g 265 t
ORIGIN
1 atgcaggggc cctgggtgct gctgctgctg ggcctgaggc tacagctctc cctgggcgtc
61 atcccagctg aggaggagaa cccggccttc tggaaccgcc aggcagctga ggccctggat
121 gctgccaaga agctgcagcc catccagaag gtcgccaaga acctcatcct cttcctgggc
181 gatgggttgg gggtgcccac ggtgacagcc accaggatcc taaaggggca gaagaatggc
241 aaactggggc ctgagacgcc cctggccatg gaccgcttcc catacctggc tctgtccaag
301 acatacaatg tggacagaca ggtgccagac agcgcagcca cagccacggc ctacctgtgc
361 ggggtcaagg ccaacttcca gaccatcggc ttgagtgcag ccgcccgctt taaccagtgc
421 aacacgacac gcggcaatga ggtcatctcc gtgatgaacc gggccaagca agcaggaaag
481 tcagtaggag tggtgaccac cacacgggtg cagcacgcct cgccagccgg cacctacgca
541 cacacagtga accgcaactg gtactcagat gctgacatgc ctgcctcagc ccgccaggag
601 gggtgccagg acatcgccac tcagctcatc tccaacatgg acattgacgt gatccttggc
661 ggaggccgca agtacatgtt tcccatgggg accccagacc ctgagtaccc agctgatgcc
721 agccagaatg gaatcaggct ggacgggaag aacctggtgc aggaatggct ggcaaagcac
781 cagggtgcct ggtatgtgtg gaaccgcact gagctcatgc aggcgtccct ggaccagtct
841 gtgacccatc tcatgggcct ctttgagccc ggagacacga aatatgagat cctccgagac
901 cccacactgg acccctccct gatggagatg acagaggctg ccctgcgcct gctgagcagg
961 aacccccgcg gcttctacct ctttgtggag ggcggccgca tcgaccatgg tcatcatgag
1021 ggtgtggctt accaggcagt cactgaggcg gtcatgttcg acgacgccat tgagagggcg
1081 ggccagctca ccagcgagga ggacacgctg accctcgtca ccgctgacca ctcccatgtc
1141 ttctcctttg gtggctacac cttgcgaggg agctccatct tcgggttggc ccccagcaag
1201 gctcaggaca gcaaagccta cacgtccatc ctgtacggca atggcccggg ctacgtgttc
1261 aactcaggcg tgcgaccaga cgtgaatgag agcgagagcg ggagccccga ttaccagcag
1321 caggcggcgg tgcccctgtc gtccgagacc cacggaggcg aagacgtggc ggtgtttgcg
1381 cgcggcccgc aggcgcacct ggtgcatggt gtgcaggagc agagcttcgt agcgcatgtc
1441 atggccttcg ctgcctgtct ggagccctac acggcctgcg acctggcgct ccccgcctgc
1501 accaccgacg ccgcgcaccc agttgccgcg tcgctgccac tgctggccgg gaccctgctg
1561 ctgctggggg cgtccgctgc tccctga
//