LOCUS HUMMHB44 1500 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human MHC class I HLA-B44 mRNA, partial cds.
ACCESSION M15470
VERSION M15470.1
KEYWORDS antigen; class I gene; glycoprotein; histocompatibility antigen;
major histocompatibility complex.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1500)
AUTHORS Kottmann,A.H., Seemann,G.H., Guessow,H.D. and Roos,M.H.
TITLE DNA sequence of the coding region of the HLA-B44 gene
JOURNAL Immunogenetics 23 (6), 396-400 (1986)
PUBMED 3459708
COMMENT Original source text: Human (Epstein-Barr virus-transformed B
lymphoblastoid cells), cDNA to mRNA, clone pBau2.
Draft entry and clean copy of sequence [1] kindly provided by
M.H.Roos, 05-MAY-1987.
FEATURES Location/Qualifiers
source 1..1500
/db_xref="H-InvDB:HIT000194397"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="6p21.3"
gene 1..1500
/gene="HLA-B"
CDS <1..1080
/gene="HLA-B"
/note="MHC HLA-B44"
/codon_start=1
/protein_id="AAA59619.1"
/db_xref="GDB:G00-120-048"
/translation="TAPRTLLLLLWGAVALTETWAGSHSMRYFYTAMSRPGRGEPRFI
TVGYVDDTLFVRFDSDATSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRENLRTA
ARYYNQSEAGSHIIQRMYGCDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSWTAADTA
AQITQRKWEAARVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDH
EATLRCWSLGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSS
GGKGGSYSQAACSDSAQGSDVSLTA"
sig_peptide <1..63
/gene="HLA-B"
/note="MHC HLA-B44 signal peptide"
mat_peptide 64..1077
/gene="HLA-B"
/product="MHC HLA-B44 mature peptide"
BASE COUNT 321 a 434 c 448 g 297 t
ORIGIN 600 bp upstream of PstI site.
1 acggcgcccc gaaccctcct cctgctgctc tggggggcag tggccctgac cgagacctgg
61 gccggctccc actccatgag gtatttctac accgccatgt cccggcccgg ccgcggggag
121 ccccgcttca tcaccgtggg ctacgtggac gacacgctgt tcgtgaggtt cgacagcgac
181 gccacgagtc cgaggaagga gccgcgggcg ccatggatag agcaggaggg gccggagtat
241 tgggaccggg agacacagat ctccaagacc aacacacaga cttaccgaga gaacctgcgc
301 accgctgccc gctactacaa ccagagcgag gccgggtctc acatcatcca gaggatgtac
361 ggctgcgacg tggggccgga cgggcgcctc ctccgcgggt atgaccagga cgcctacgac
421 ggcaaggatt acatcgccct gaacgaggac ctgagctcct ggaccgcggc ggacaccgcc
481 gctcagatca cccagcgcaa gtgggaggcg gcccgtgtgg cggagcagga cagagcctac
541 ctggagggcc tgtgcgtgga gtcgctccgc agatacctgg agaacgggaa ggagacgctg
601 cagcgcgcgg accccccaaa gacacatgtg acccaccacc ccatctctga ccatgaggcc
661 accctgaggt gctggtccct gggcttctac cctgcggaga tcacactgac ctggcagcgg
721 gatggcgagg accaaactca ggacaccgag cttgtggaga ccagaccagc aggagataga
781 accttccaga agtgggcagc tgtggtggtg ccttctggag aagagcagag atacacatgc
841 catgtacagc atgaggggct gccgaagccc ctcaccctga gatgggagcc gtcttcccag
901 tccaccgtcc ccatcgtggg cattgttgct ggcctggctg tcctagcagt tgtggtcatc
961 ggagctgtgg tcgctgctgt gatgtgtagg aggaagagct caggtggaaa aggagggagc
1021 tactctcagg ctgcgtgcag cgacagtgcc cagggctctg atgtgtctct cacagcttga
1081 aaagcctgag acagctgtct tgtgagggac tgagatgcag gatttcttca cgcctcccct
1141 ttgtgacttc aagagcctct ggctctcttt ctgcaaaggc acctgaatgt gtctgcgtcc
1201 ctgttagcat aatgtgagga ggtggagaga cagcccaccc ccgtgtccac cgtgacccct
1261 gttcccatgc tgacttgtgt ttcctcccca gtcatctttc ctgttccaga gaggtggggc
1321 tggatgtctc catctctgtc tcaattttat gtgcactgag ctgcaacttc ttacttccct
1381 actgaaataa gaatctgaat ataaatttgt tttctcaaat atttgctatg agaggttgat
1441 ggattaatta aataagtcaa ttcctggaat ttgagagagc aaataaagac ctgagaacct
//