LOCUS HUMIF4E 1842 bp mRNA linear HUM 01-SEP-1995
DEFINITION Homo sapiens cap-binding protein mRNA, complete cds.
ACCESSION M15353
VERSION M15353.1
KEYWORDS cap-binding protein; eIF-4E gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1842)
AUTHORS Rychlik,W., Domier,L.L., Gardner,P.R., Hellmann,G.M. and
Rhoads,R.E.
TITLE Amino acid sequence of the mRNA cap-binding protein from human
tissues
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (4), 945-949 (1987)
PUBMED 3469651
COMMENT On Jul 26, 1993 this sequence version replaced gi:179973.
Original source text: Homo sapiens (clone library: library of J.
Whittaker) cDNA to mRNA.
Draft entry and computer-readable sequence for [1] kindly provided
by L.Domier, 21-APR-1987.
There are at least two species of CBP mRNA of about 1900 and 2500
nucleotides each. There may be alternative start sites. Potential
polyadenylation signals are located at positions 1315-1320,
1621-1626, and 1811-1816.
FEATURES Location/Qualifiers
source 1..1842
/db_xref="H-InvDB:HIT000194390"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="IM9"
/cell_type="lymphocyte"
/clone_lib="library of J. Whittaker"
mRNA <1..1842
/product="CBP mRNA"
CDS 19..672
/codon_start=1
/product="cap-binding protein"
/protein_id="AAC13647.1"
/translation="MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWA
LWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMW
EDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKG
DKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV"
regulatory 1314..1319
/regulatory_class="polyA_signal_sequence"
regulatory 1620..1625
/regulatory_class="polyA_signal_sequence"
regulatory 1810..1815
/regulatory_class="polyA_signal_sequence"
polyA_site 1842
BASE COUNT 550 a 310 c 338 g 644 t
ORIGIN
1 cgatcagatc gatctaagat ggcgactgtc gaaccggaaa ccacccctac tcctaatccc
61 ccgactacag aagaggagaa aacggaatct aatcaggagg ttgctaaccc agaacactat
121 attaaacatc ccctacagaa cagatgggca ctctggtttt ttaaaaatga taaaagcaaa
181 acttggcaag caaacctgcg gctgatctcc aagtttgata ctgttgaaga cttttgggct
241 ctgtacaacc atatccagtt gtctagtaat ttaatgcctg gctgtgacta ctcacttttt
301 aaggatggta ttgagcctat gtgggaagat gagaaaaaca aacggggagg acgatggcta
361 attacattga acaaacagca gagacgaagt gacctcgatc gcttttggct agagacactt
421 ctgtgcctta ttggagaatc ttttgatgac tacagtgatg atgtatgtgg cgctgttgtt
481 aatgttagag ctaaaggtga taagatagca atatggacta ctgaatgtga aaacagagaa
541 gctgttacac atatagggag ggtatacaag gaaaggttag gacttcctcc aaagatagtg
601 attggttatc agtcccacgc agacacagct actaagagcg gctccaccac taaaaatagg
661 tttgttgttt aagaagacac cttctgagta ttctcatagg agactgcgtc aagcaatcga
721 gatttgggag ctgaaccaaa gcctcttcaa aaagcagagt ggactgcatt taaatttgat
781 ttccatctta atgttactca gatataagag aagtctcatt cgcctttgtc ttgtacttct
841 gtgttcattt tttttttttt tttttggcta gagtttccac tatcccaatc aaagaattac
901 agtacacatc cccagaatcc ataaatgtgt tcctggccca ctctgtaata gttcagtaga
961 attaccatta attacataca gattttacct atccacaata gtcagaaaac aacttggcat
1021 ttctatactt tacaggaaaa aaaattctgt tgttccattt tatgcagaag catattttgc
1081 tggtttgaaa gattatgatg catacagttt tctagcaatt ttctttgttt ctttttacag
1141 cattgtcttt gctgtactct tgctgatggc tgctagattt taatttattt gtttccctac
1201 ttgataatat tagtgattct gatttcagtt tttcatttgt tttgcttaaa tttttttttt
1261 ttttttcctc atgtaacatt ggtgaaggat ccaggaatat gacacaaagg tggaataaac
1321 attaattttg tgcattcttt ggtaattttt tttgtttttt gtaactacaa agctttgcta
1381 caaatttatg catttcattc aaatcagtga tctatgtttg tgtgatttcc taaacataat
1441 tgtggattat aaaaaatgta acatcataat tacattccta actagaatta gtatgtctgt
1501 ttttgtatct ttatgctgta ttttaacact ttgtattact taggttattt tgctttggtt
1561 aaaaatggct caagtagaaa agcagtccca ttcatattaa gacagtgtac aaaactgtaa
1621 ataaaatgtg tacagtgaat tgtcttttag acaactagat ttgtcctttt atttctccat
1681 ctttatagaa ggaatttgta cttcttattg caggcaagtc tctatattat gtcctctttt
1741 gtggtgtctt ccatgtgaac agcataagtt tggagcacta gtttgattat tatgtttatt
1801 acaattttta ataaattgaa taggtagtat catatatatg ga
//