LOCUS HUMCKMA 1562 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human creatine kinase M mRNA, complete cds.
ACCESSION M14780
VERSION M14780.1
KEYWORDS creatine kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1562)
AUTHORS Perryman,M.B., Kerner,S.A., Bohlmeyer,T.J. and Roberts,R.
TITLE Isolation and sequence analysis of a full-length cDNA for human M
creatine kinase
JOURNAL Biochem. Biophys. Res. Commun. 140 (3), 981-989 (1986)
PUBMED 3778496
COMMENT Original source text: Human skeletal muscle, cDNA to mRNA (library
of Gunning et al.), clone pHMCK1.
FEATURES Location/Qualifiers
source 1..1562
/db_xref="H-InvDB:HIT000194366"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19q13.3"
gene 1..1562
/gene="CKM"
mRNA 1..1562
/gene="CKM"
/product="CK mRNA"
CDS 79..1224
/gene="CKM"
/EC_number="2.7.3.2"
/note="precursor"
/codon_start=1
/product="creatine kinase M"
/protein_id="AAA52025.1"
/db_xref="GDB:G00-120-591"
/translation="MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRD
KEIPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKP
TDKHKTDLNHENLKGGDDLDPNYVLSSPVRTGRSIKGYTLPPHCSRGERRAVEKLSVE
ALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFQFDKPVSPLLLASGMARHWPDAPGIW
HNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQH
LGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGAVDTAAVGSVF
DVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK"
mat_peptide 82..1221
/gene="CKM"
/product="creatine kinase M"
BASE COUNT 359 a 489 c 425 g 289 t
ORIGIN 136 bp upstream of RsaI site; chromosmoe 19q13.
1 gtgggtcagc atgtcacctc caggatacag acagcccccc ttcagcccag cccagccagg
61 tctccttaca ccgccaccat gccattcggt aacacccaca acaagttcaa gctgaattac
121 aagcctgagg aggagtaccc cgacctcagc aaacataaca accacatggc caaggtactg
181 acccttgaac tctacaagaa gctgcgggac aaggagatcc catctggctt cactgtagac
241 gatgtcatcc agacaggagt ggacaaccca ggtcacccct tcatcatgac cgtgggctgc
301 gtggctggtg atgaggagtc ctacgaagtt ttcaaggaac tctttgaccc catcatctcg
361 gatcgccacg ggggctacaa acccactgac aagcacaaga ctgacctcaa ccatgaaaac
421 ctcaagggtg gagacgacct ggaccccaac tacgtgctca gcagcccggt ccgcactggc
481 cgcagcatca agggctacac gttgccccca cactgctccc gtggcgagcg ccgggcggtg
541 gagaagctct ctgtggaagc tctcaacagc ctgacgggcg agttcaaagg gaagtactac
601 cctctgaaga gcatgacgga gaaggagcag cagcagctca tcgatgacca cttccagttc
661 gacaagcccg tgtccccgct gctgctggcc tcaggcatgg cccgccactg gcccgacgcc
721 cctggcatct ggcacaatga caacaagagc ttcctggtgt gggtgaacga ggaggatcac
781 ctccgggtca tctccatgga gaaggggggc aacatgaagg aggttttccg ccgcttctgc
841 gtagggctgc agaagattga ggagatcttt aagaaagctg gccacccctt catgtggaac
901 cagcacctgg gctacgtgct cacctgccca tccaacctgg gcactgggct gcgtggaggc
961 gtgcatgtga agctggcgca cctgagcaag caccccaagt tcgaggagat cctcacccgc
1021 ctgcgtctgc agaagagggg tacaggtgcg gtggacacag ctgccgtggg ctcagtattt
1081 gacgtgtcca acgctgatcg gctgggctcg tccgaagtag aacaggtgca gctggtggtg
1141 gatggtgtga agctcatggt ggaaatggag aagaagttgg agaaaggcca gtccatcgac
1201 gacatgatcc ccgcccagaa gtaggcgcct gcccacctgc caccgactgc tggaacccca
1261 gccagtggga gggcctggcc caccagagtc ctgctccctc actcctcgcc ccgccccctg
1321 tcccagagtc cacctggggg ctctctccac ccttctcaga gttccagttt caaccagagt
1381 tccaaccaat gggctccatc ctctggattc tggccaatga aatatctccc tggcagggtc
1441 ctcttctttt cccagagctc ctccccaacc aggagctcta gttaatggag agctcccagc
1501 acactcggac gcttgtgctt ttgtctccac gcaaacggat aaataaaagc attggtggcc
1561 tt
//