LOCUS HUMARGL 1445 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human liver arginase mRNA, complete cds.
ACCESSION M14502
VERSION M14502.1
KEYWORDS arginase; liver arginase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1445)
AUTHORS Haraguchi,Y., Takiguchi,M., Amaya,Y., Kawamoto,S., Matsuda,I. and
Mori,M.
TITLE Molecular cloning and nucleotide sequence of cDNA for human liver
arginase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (2), 412-415 (1987)
PUBMED 3540966
COMMENT Original source text: Human liver, cDNA to mRNA, library of
G.A.Ricca, clone lambda-phARG6; primer library of Y.Ebina, clone
lambda-hERG109.
Clean copy sequence for [1] kindly provided by M.Mori, 18-FEB-1987.
FEATURES Location/Qualifiers
source 1..1445
/db_xref="H-InvDB:HIT000194336"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="6q23"
gene 1..1445
/gene="ARG1"
mRNA <1..1445
/gene="ARG1"
/product="arg mRNA"
CDS 57..1025
/gene="ARG1"
/note="arginase (EC 3.5.3.1)"
/codon_start=1
/protein_id="AAA51776.1"
/db_xref="GDB:G00-119-006"
/translation="MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQE
CDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAQVKKNGRISLVLGGDHS
LAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVP
GFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSY
LLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIM
EVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK"
BASE COUNT 465 a 287 c 328 g 365 t
ORIGIN 12 bp upstream of HincII site; chromosome 6q23.
1 tcactgaggg ttgactgact ggagagctca agtgcagcaa agagaagtgt cagagcatga
61 gcgccaagtc cagaaccata gggattattg gagctccttt ctcaaaggga cagccacgag
121 gaggggtgga agaaggccct acagtattga gaaaggctgg tctgcttgag aaacttaaag
181 aacaagagtg tgatgtgaag gattatgggg acctgccctt tgctgacatc cctaatgaca
241 gtccctttca aattgtgaag aatccaaggt ctgtgggaaa agcaagcgag cagctggctg
301 gcaaggtggc acaagtcaag aagaacggaa gaatcagcct ggtgctgggc ggagaccaca
361 gtttggcaat tggaagcatc tctggccatg ccagggtcca ccctgatctt ggagtcatct
421 gggtggatgc tcacactgat atcaacactc cactgacaac cacaagtgga aacttgcatg
481 gacaacctgt atctttcctc ctgaaggaac taaaaggaaa gattcccgat gtgccaggat
541 tctcctgggt gactccctgt atatctgcca aggatattgt gtatattggc ttgagagacg
601 tggaccctgg ggaacactac attttgaaaa ctctaggcat taaatacttt tcaatgactg
661 aagtggacag actaggaatt ggcaaggtga tggaagaaac actcagctat ctactaggaa
721 gaaagaaaag gccaattcat ctaagttttg atgttgacgg actggaccca tctttcacac
781 cagctactgg cacaccagtc gtgggaggtc tgacatacag agaaggtctc tacatcacag
841 aagaaatcta caaaacaggg ctactctcag gattagatat aatggaagtg aacccatccc
901 tggggaagac accagaagaa gtaactcgaa cagtgaacac agcagttgca ataaccttgg
961 cttgtttcgg acttgctcgg gagggtaatc acaagcctat tgactacctt aacccaccta
1021 agtaaatgtg gaaacatccg atataaatct catagttaat ggcataatta gaaagctaat
1081 cattttctta agcatagagt tatccttcta aagacttgtt ctttcagaaa aatgtttttc
1141 caattagtat aaactctaca aattccctct tggtgtaaaa ttcaagatgt ggaaattcta
1201 acttttttga aatttaaaag cttatatttt ctaacttggc aaaagactta tccttagaaa
1261 gagaagtgta cattgatttc caattaaaaa tttgctggca ttaaaaataa gcacacttac
1321 ataagccccc atacatagag tgggactctt ggaatcagga gacaaagcta ccacatgtgg
1381 aaaggtacta tgtgtccatg tcattcaaaa aatgtgattt tttataataa actctttata
1441 acaag
//